Histone Methyltransferase - 表观遗传学 - 按“信号通路”分类 - 小分子和化合物库

添加到收藏夹比较

BIX-01294,G9a和G9a样蛋白组蛋白甲基转移酶抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 935693-62-2 Compound CID : 25150857

分子式: C₂₈H₃₈N₆O₂ 分子量: 490.64

IUPAC Name: N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine

SMILES: CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC

InChIKey: OSXFATOLZGZLSK-UHFFFAOYSA-N

InChI: InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)

详情

查看价格关闭

添加到收藏夹比较

毛壳素

规格或纯度 :

Moligand™

≥98%

CAS号 : 28097-03-2 Compound CID : 11657687

分子式: C₃₀H₂₈N₆O₆S₄ 分子量: 696.84

IUPAC Name: (1S,3R,11R,14S)-14-(hydroxymethyl)-3-[(1S,3R,11R,14S)-14-(hydroxymethyl)-18-methyl-13,17-dioxo-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-trien-3-yl]-18-methyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-triene-13,17-dione

SMILES: CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C

InChIKey: PZPPOCZWRGNKIR-PNVYSBBASA-N

InChI: InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32,37-38H,11-14H2,1-2H3/t19-,20-,25+,26+,27+,28+,29+,30+/m1/s1

详情

查看价格关闭

添加到收藏夹比较

Pinometostat (EPZ5676)

规格或纯度 :

Moligand™

≥98%

CAS号 : 1380288-87-8 Compound CID : 57345410

分子式: C₃₀H₄₂N₈O₃ 分子量: 562.71

IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol

SMILES: CC(C)N(CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C

InChIKey: LXFOLMYKSYSZQS-XKHGBIBOSA-N

InChI: InChI=1S/C30H42N8O3/c1-16(2)37(13-22-25(39)26(40)29(41-22)38-15-34-24-27(31)32-14-33-28(24)38)19-10-17(11-19)6-9-23-35-20-8-7-18(30(3,4)5)12-21(20)36-23/h7-8,12,14-17,19,22,25-26,29,39-40H,6,9-11,13H2,1-5H3,(H,35,36)(H2,31,32,33)/t17?,19?,22-,25-,26-,29-/m1/s1

详情

查看价格关闭

添加到收藏夹比较

EPZ005687,EZH2抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 1396772-26-1 Compound CID : 60160561

分子式: C₃₂H₃₇N₅O₃ 分子量: 539.67

IUPAC Name: 1-cyclopentyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[4-(morpholin-4-ylmethyl)phenyl]indazole-4-carboxamide

SMILES: CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC=C(C=C4)CN5CCOCC5)C6CCCC6)C

InChIKey: ZOIBZSZLMJDVDQ-UHFFFAOYSA-N

InChI: InChI=1S/C32H37N5O3/c1-21-15-22(2)35-32(39)28(21)18-33-31(38)27-16-25(17-30-29(27)19-34-37(30)26-5-3-4-6-26)24-9-7-23(8-10-24)20-36-11-13-40-14-12-36/h7-10,15-17,19,26H,3-6,11-14,18,20H2,1-2H3,(H,33,38)(H,35,39)

详情

查看价格关闭

添加到收藏夹比较

GSK126,EZH2甲基转移酶抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 1346574-57-9 Compound CID : 68210102

分子式: C₃₁H₃₈N₆O₂ 分子量: 526.67

IUPAC Name: 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-methyl-6-(6-piperazin-1-ylpyridin-3-yl)indole-4-carboxamide

SMILES: CCC(C)N1C=C(C2=C(C=C(C=C21)C3=CN=C(C=C3)N4CCNCC4)C(=O)NCC5=C(C=C(NC5=O)C)C)C

InChIKey: FKSFKBQGSFSOSM-QFIPXVFZSA-N

InChI: InChI=1S/C31H38N6O2/c1-6-22(5)37-18-20(3)29-25(30(38)34-17-26-19(2)13-21(4)35-31(26)39)14-24(15-27(29)37)23-7-8-28(33-16-23)36-11-9-32-10-12-36/h7-8,13-16,18,22,32H,6,9-12,17H2,1-5H3,(H,34,38)(H,35,39)/t22-/m0/s1

详情

查看价格关闭

添加到收藏夹比较

GSK343,细胞可穿透的histone H3-赖氨酸27（H3K27）甲基转移酶EZH2抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 1346704-33-3 Compound CID : 71268957

分子式: C₃₁H₃₉N₇O₂ 分子量: 541.69

IUPAC Name: N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide

SMILES: CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C

InChIKey: ULNXAWLQFZMIHX-UHFFFAOYSA-N

InChI: InChI=1S/C31H39N7O2/c1-6-7-23-14-21(4)35-31(40)26(23)18-33-30(39)25-15-24(16-28-27(25)19-34-38(28)20(2)3)22-8-9-32-29(17-22)37-12-10-36(5)11-13-37/h8-9,14-17,19-20H,6-7,10-13,18H2,1-5H3,(H,33,39)(H,35,40)

详情

查看价格关闭

添加到收藏夹比较

BIX 01294三盐酸盐

规格或纯度 :

≥98%

CAS号 : 1392399-03-9 Compound CID : 46945860

分子式: C₂₈H₄₁Cl₃N₆O₂ 分子量: 600.03

IUPAC Name: N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine;trihydrochloride

SMILES: CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC.Cl.Cl.Cl

InChIKey: FMURUEPQXKJIPS-UHFFFAOYSA-N

InChI: InChI=1S/C28H38N6O2.3ClH/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21;;;/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31);3*1H

详情

查看价格关闭

添加到收藏夹比较

C 7280948,PRMT1抑制剂

规格或纯度 :

≥98%

CAS号 : 587850-67-7 Compound CID : 833539

分子式: C₁₄H₁₆N₂O₂S 分子量: 276.36

IUPAC Name: 4-amino-N-(2-phenylethyl)benzenesulfonamide

SMILES: C1=CC=C(C=C1)CCNS(=O)(=O)C2=CC=C(C=C2)N

InChIKey: BYWZPUPRVIECEC-UHFFFAOYSA-N

InChI: InChI=1S/C14H16N2O2S/c15-13-6-8-14(9-7-13)19(17,18)16-11-10-12-4-2-1-3-5-12/h1-9,16H,10-11,15H2

详情

查看价格关闭

添加到收藏夹比较

AMI 1,可逆蛋白精氨酸甲基转移酶抑制剂

规格或纯度 :

≥98%

CAS号 : 20324-87-2 Compound CID : 88489

分子式: C₂₁H₁₄N₂Na₂O₉S₂ 分子量: 548.45

IUPAC Name: disodium;4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate

SMILES: C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+]

InChIKey: MOUNHKKCIGVIDI-UHFFFAOYSA-L

InChI: InChI=1S/C21H16N2O9S2.2Na/c24-19-9-15(33(27,28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30,31)32;;/h1-10,24-25H,(H2,22,23,26)(H,27,28,29)(H,30,31,32);;/q;2*+1/p-2

详情

查看价格关闭

添加到收藏夹比较

3-脱氮胸腺素A

规格或纯度 :

≥98%

CAS号 : 102052-95-9 Compound CID : 73087

分子式: C₁₂H₁₄N₄O₃ 分子量: 262.26

IUPAC Name: (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol

SMILES: C1=CN=C(C2=C1N(C=N2)C3C=C(C(C3O)O)CO)N

InChIKey: OMKHWTRUYNAGFG-IEBDPFPHSA-N

InChI: InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8-,10-,11+/m1/s1

详情

查看价格关闭

添加到收藏夹比较

MS023,细胞活性PRMT抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 1831110-54-3 Compound CID : 92136227

分子式: C₁₇H₂₅N₃O 分子量: 287.4

IUPAC Name: N'-methyl-N'-[[4-(4-propan-2-yloxyphenyl)-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine

SMILES: CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN

InChIKey: FMTVWAGUJRUAKE-UHFFFAOYSA-N

InChI: InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3

详情

查看价格关闭

添加到收藏夹比较

抑制剂6e（PRMT1抑制剂6e）

规格或纯度 :

≥98%

CAS号 : 1025948-98-4 Compound CID : 16116049

分子式: C₂₀H₇Br₆NO₅ 分子量: 820.7

IUPAC Name: 4-amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid

SMILES: C1=C2C(=C3C=C(C(=O)C(=C3OC2=C(C(=C1Br)O)Br)Br)Br)C4=C(C(=C(C=C4C(=O)O)Br)N)Br

InChIKey: PSILLVDSFALROT-UHFFFAOYSA-N

InChI: InChI=1S/C20H7Br6NO5/c21-7-3-6(20(30)31)11(12(24)15(7)27)10-4-1-8(22)16(28)13(25)18(4)32-19-5(10)2-9(23)17(29)14(19)26/h1-3,28H,27H2,(H,30,31)

详情

查看价格关闭