| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| R128623-25mg |
25mg |
期货  |
| |
| R128623-100mg |
100mg |
现货 |
|
| 产品名称 | 核糖核酸酶 B 来源于牛胰腺 |
|---|---|
| 英文别名 | 9001-99-4 | Nuclease, ribo- | L-HISTIDINE, N-beta-ALANYL- | 2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid | 9001-73-4 | DL-(3-aminopropanoyl)histidine | 108333-82-0 | 2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid | beta-Alanylhistidine | L-Histid |
| 规格或纯度 | EnzymoPure™, ≥1,000 units/mg dry weight |
| 产品介绍 |
Pancreatic ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5. Ribonuclease B has a molecular weight of 14,700 ± 300 daltons. It is a glycoprotein which possesses an amino acid composition indistinguishable from that of RNase A. It contains 6 residues of mannose and 2 residues of N-acetylglucosamine per molecule. It is a glycosylated derivative of RNase A. Ribonuclease is inhibited by heavy metal ions and it is competitively inhibited by DNA. Since Molecular Biology Grade RNase A (Product R128619) is essentially free of DNase and protease activities, this product is useful in removing RNA from DNA in nucleic acid work and where other enzymes are used or where intact proteins must be recovered. Product Describtion: Pancreatic ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5. Ribonuclease B has a molecular weight of 14,700 ± 300 daltons. It is a glycoprotein which possesses an amino acid composition indistinguishable from that of RNase A. It contains 6 residues of mannose and 2 residues of N-acetylglucosamine per molecule. It is a glycosylated derivative of RNase A. Ribonuclease is inhibited by heavy metal ions and it is competitively inhibited by DNA. Since Molecular Biology Grade RNase A (Product R128619) is essentially free of DNase and protease activities, this product is useful in removing RNA from DNA in nucleic acid work and where other enzymes are used or where intact proteins must be recovered.R128623 is a partially purified preparation containing a mixture of RNase A and RNase B. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 浓度 | ≥1,000 units/mg dry weight |
|---|---|
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| CAS编号和信息 | 9001-99-4 |
| 酶学委员会编号 | I.U.B.: 3.1.27.5 |
| 单位定义 | One Kalnitsky Unit causes an increase in absorbance of 1.0 at 260nm at 37°C and pH 5.0 when yeast ribosomal RNA is hydrolyzed to acid soluble oliognucleotides. One Kunitz unit equals 50 Worthington units. |
| 分子类型 | 小分子 |
| Enzymatic Activity(Dry Basis) | ≥1000（units/mg） |
|---|---|
| Appearance（R128623) | lyophilized powder |
| RNase B(SDS PAGE) | ≥50（%） |
¥195.90
¥772.90
¥899.90
¥78.90
¥699.90
¥2,249.90
| 1. Ningning Lei, Xu Peng, Mengyue Hu, Chang Wan, Xixun Yu. (2023) Research on essential performance of oxidized chitosan-crosslinked acellular porcine aorta modified with bioactive SCPP/DOPA for esophageal scaffold with enhanced mechanical strength, biocompatibility and anti-inflammatory. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 241 (124522). [PMID:37100332] [10.1016/j.ijbiomac.2023.124522] |
| 2. Qing Liu, Chao Yan, Yan Wang. (2023) Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC. MOLECULES, 28 (8): (3542). [PMID:37110774] [10.3390/molecules28083542] |
| 3. Tingting Wu, Xushun Liu, Hanjun Chen, Ying Liu, Yu Cao. (2023) An in situ exosomal miRNA sensing biochip based on multi-branched localized catalytic hairpin assembly and photonic crystals. BIOSENSORS & BIOELECTRONICS, 222 (115013). [PMID:36529054] [10.1016/j.bios.2022.115013] |
| 4. Hui-Zhen Zhang, Mei Shu, Wen-Yu Yang, Hong Pan, Men-Xuan Tang, Yuan-Yang Zhao, Chan Zhong, Guo-Ping Wu. (2023) Isolation and characterization of a novel Salmonella bacteriophage JNwz02 capable of lysing Escherichia coli O157:H7 and its antibacterial application in foods. LWT-FOOD SCIENCE AND TECHNOLOGY, 173 (114251). [10.1016/j.lwt.2022.114251] |
| 5. Can Cheng, Xu Peng, Linjie Xi, Yihao Luo, Yuhang Wang, Yufan Zhou, Xixun Yu. (2022) Feasibility study of oxidized naringin as a novel crosslinking agent for crosslinking decellularized porcine Achilles tendon and its potential application for anterior cruciate ligament repair. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 111 (2): (170-184). [PMID:36054309] [10.1002/jbm.a.37440] |
| 6. Zhi-Heng Pan, Shi-Song Yu, Chen-Chen Bai, Wen-Yu Yin, Yi-Rong Ma, Zi-Ang Xue, Qin-Yue Lu, Lin-Yi Dong, Xian-Hua Wang. (2022) Poly(caffeic acid)-coated molecularly imprinted magnetic nanoparticles for specific and ultrasensitive detection of glycoprotein. TALANTA, 241 (123240). [PMID:35065346] [10.1016/j.talanta.2022.123240] |
| 7. Shuwen Guo, Qiaoxian Huang, Jianwen Wei, Shengpeng Wang, Yitao Wang, Leyong Wang, Ruibing Wang. (2022) Efficient intracellular delivery of native proteins facilitated by preorganized guanidiniums on pillar[5]arene skeleton. Nano Today, 43 (101396). [10.1016/j.nantod.2022.101396] |
| 8. Jiasheng Shi, Henan Zhang, Qian Wang, Zhengyu Duan, Li Xu, Fenghao Guo, Yunfeng Xie, Zhiyong Chen. (2022) Biomimetic rigid cryogels with aligned micro-sized tubular structures prepared by conventional redox-induced cryopolymerization in a freezer. CHEMICAL ENGINEERING JOURNAL, 427 (131903). [10.1016/j.cej.2021.131903] |
| 9. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785] [10.1088/1748-605X/ac0088] |
| 10. Jie Xing, Fang Wang, Hailin Cong, Song Wang, Youqing Shen, Bing Yu. (2021) Analysis of proteins and chiral drugs based on vancomycin covalent capillary electrophoretic coating. ANALYST, 146 (4): (1320-1325). [PMID:33367313] [10.1039/D0AN02018D] |
| 11. Rui Duan, Chao Peng, Lu Sun, Lu-Xia Zhang, Chen-Chen Bai, Lin-Yi Dong, Xian-Hua Wang. (2021) Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein. SENSORS AND ACTUATORS B-CHEMICAL, 330 (129310). [10.1016/j.snb.2020.129310] |
| 12. Yu Luo, Lie Ma. (2020) Bioprosthetic heart valves with reduced immunogenic residuals using vacuum-assisted decellularization treatment. Biomedical Materials, 15 (6): (65012). [PMID:33016260] [10.1088/1748-605X/abaabf] |
| 13. Jie Xing, Ming-Hong Wang, Song Wang, Hai-Lin Cong, You-Qing Shen, Bing Yu. (2020) Analysis of proteins by capillary electrophoresis with a novel diazoresin/β-Cyclodextrin covalent capillary coating method. FERROELECTRICS, [10.1080/00150193.2020.1760608] |
| 14. Qiuyue Sha, Ruixue Guan, Huiying Su, Liang Zhang, Bi-Feng Liu, Zhaoyu Hu, Xin Liu. (2020) Carbohydrate-protein template synthesized high mannose loading gold nanoclusters: A powerful fluorescence probe for sensitive Concanavalin A detection and specific breast cancer cell imaging. TALANTA, 218 (121130). [PMID:32797887] [10.1016/j.talanta.2020.121130] |
| 15. Ying Jia, Han Gao, Mengmeng Tong, Donald M. Anderson. (2019) Cell cycle regulation of the mixotrophic dinoflagellate Dinophysis acuminata: Growth, photosynthetic efficiency and toxin production. HARMFUL ALGAE, 89 (101672). [PMID:31672228] [10.1016/j.hal.2019.101672] |
| 16. Yameng Han, Zhongju Ye, Fuyan Wang, Tianyu Chen, Lin Wei, Langxing Chen, Lehui Xiao. (2019) Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles. Nanoscale, 11 (31): (14793-14801). [PMID:31353389] [10.1039/C9NR01817D] |
| 17. Wei Chen, Min Fu, Xixi Zhu, Qingyun Liu. (2019) A close-packed imprinted colloidal array for naked-eye detection of glycoproteins under physiological pH. BIOSENSORS & BIOELECTRONICS, 142 (111499). [PMID:31306955] [10.1016/j.bios.2019.111499] |
| 18. Yu Luo, Dong Lou, Lie Ma, Changyou Gao. (2019) Optimizing detergent concentration and processing time to balance the decellularization efficiency and properties of bioprosthetic heart valves. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 107 (10): (2235-2243). [PMID:31125175] [10.1002/jbm.a.36732] |
| 19. Manman Han, Wan Li, Rui Chen, Yangyang Han, Xiuhua Liu, Tingting Wang, Huaizhong Guo, Xiaoqiang Qiao. (2018) Amino acid and ionic liquid modified polyhedral oligomeric silsesquioxane-based hybrid monolithic column for high-efficiency capillary liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1572 (82). [PMID:30153983] [10.1016/j.chroma.2018.08.045] |
| 20. Qi-Qing LI, Jian ZHANG, Ji-Hua LIU, Bo-Yang YU. (2018) Morphological and chemical studies of artificial Andrographis paniculata polyploids. Chinese Journal of Natural Medicines, 16 (81). [PMID:29455732] [10.1016/S1875-5364(18)30033-5] |
| 21. Yi Hao, Ruixia Gao, Dechun Liu, Gaiyan He, Yuhai Tang, Zengjun Guo. (2016) A facile and general approach for preparation of glycoprotein-imprinted magnetic nanoparticles with synergistic selectivity. TALANTA, 153 (211). [PMID:27130111] [10.1016/j.talanta.2016.03.005] |
| 22. Yu Tian, Yunfang Li, Jie Mei, Bo Cai, Jinfeng Dong, Zhiguo Shi, Yuxiu Xiao. (2015) Simultaneous separation of acidic and basic proteins using gemini pyrrolidinium surfactants and hexafluoroisopropanol as dynamic coating additives in capillary electrophoresis. JOURNAL OF CHROMATOGRAPHY A, 1412 (151). [PMID:26300480] [10.1016/j.chroma.2015.08.020] |
| 23. Yuanting Xu, Chengcheng Huang, Li Li, Xixun Yu, Xu Wang, Hong Peng, Zhipeng Gu, Yaping Wang. (2013) In vitro enzymatic degradation of a biological tissue fixed by alginate dialdehyde. CARBOHYDRATE POLYMERS, 95 (148). [PMID:23618251] [10.1016/j.carbpol.2013.03.021] |
| 24. Yuanting Xu, Li Li, Hao Wang, Xixun Yu, Zhipeng Gu, Chengcheng Huang, Hong Peng. (2013) In vitro cytocompatibility evaluation of alginate dialdehyde for biological tissue fixation. CARBOHYDRATE POLYMERS, 92 (448). [PMID:23218319] [10.1016/j.carbpol.2012.09.096] |
| 25. Yujie Zhang,Renling Lu,Ming Chen,Shouyong Zhou,Dabing Zhang,Haifeng Han,Mingliang Zhang,Hongdeng Qiu. (2020-08-17) A highly efficient acyl-transfer approach to urea-functionalized silanes and their immobilization onto silica gel as stationary phases for liquid chromatography.. Journal of chromatography. A, 1626 (461366-461366). [PMID:32797845] |
| 1. Ningning Lei, Xu Peng, Mengyue Hu, Chang Wan, Xixun Yu. (2023) Research on essential performance of oxidized chitosan-crosslinked acellular porcine aorta modified with bioactive SCPP/DOPA for esophageal scaffold with enhanced mechanical strength, biocompatibility and anti-inflammatory. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 241 (124522). [PMID:37100332] [10.1016/j.ijbiomac.2023.124522] |
| 2. Qing Liu, Chao Yan, Yan Wang. (2023) Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC. MOLECULES, 28 (8): (3542). [PMID:37110774] [10.3390/molecules28083542] |
| 3. Tingting Wu, Xushun Liu, Hanjun Chen, Ying Liu, Yu Cao. (2023) An in situ exosomal miRNA sensing biochip based on multi-branched localized catalytic hairpin assembly and photonic crystals. BIOSENSORS & BIOELECTRONICS, 222 (115013). [PMID:36529054] [10.1016/j.bios.2022.115013] |
| 4. Hui-Zhen Zhang, Mei Shu, Wen-Yu Yang, Hong Pan, Men-Xuan Tang, Yuan-Yang Zhao, Chan Zhong, Guo-Ping Wu. (2023) Isolation and characterization of a novel Salmonella bacteriophage JNwz02 capable of lysing Escherichia coli O157:H7 and its antibacterial application in foods. LWT-FOOD SCIENCE AND TECHNOLOGY, 173 (114251). [10.1016/j.lwt.2022.114251] |
| 5. Can Cheng, Xu Peng, Linjie Xi, Yihao Luo, Yuhang Wang, Yufan Zhou, Xixun Yu. (2022) Feasibility study of oxidized naringin as a novel crosslinking agent for crosslinking decellularized porcine Achilles tendon and its potential application for anterior cruciate ligament repair. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 111 (2): (170-184). [PMID:36054309] [10.1002/jbm.a.37440] |
| 6. Zhi-Heng Pan, Shi-Song Yu, Chen-Chen Bai, Wen-Yu Yin, Yi-Rong Ma, Zi-Ang Xue, Qin-Yue Lu, Lin-Yi Dong, Xian-Hua Wang. (2022) Poly(caffeic acid)-coated molecularly imprinted magnetic nanoparticles for specific and ultrasensitive detection of glycoprotein. TALANTA, 241 (123240). [PMID:35065346] [10.1016/j.talanta.2022.123240] |
| 7. Shuwen Guo, Qiaoxian Huang, Jianwen Wei, Shengpeng Wang, Yitao Wang, Leyong Wang, Ruibing Wang. (2022) Efficient intracellular delivery of native proteins facilitated by preorganized guanidiniums on pillar[5]arene skeleton. Nano Today, 43 (101396). [10.1016/j.nantod.2022.101396] |
| 8. Jiasheng Shi, Henan Zhang, Qian Wang, Zhengyu Duan, Li Xu, Fenghao Guo, Yunfeng Xie, Zhiyong Chen. (2022) Biomimetic rigid cryogels with aligned micro-sized tubular structures prepared by conventional redox-induced cryopolymerization in a freezer. CHEMICAL ENGINEERING JOURNAL, 427 (131903). [10.1016/j.cej.2021.131903] |
| 9. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785] [10.1088/1748-605X/ac0088] |
| 10. Jie Xing, Fang Wang, Hailin Cong, Song Wang, Youqing Shen, Bing Yu. (2021) Analysis of proteins and chiral drugs based on vancomycin covalent capillary electrophoretic coating. ANALYST, 146 (4): (1320-1325). [PMID:33367313] [10.1039/D0AN02018D] |
| 11. Rui Duan, Chao Peng, Lu Sun, Lu-Xia Zhang, Chen-Chen Bai, Lin-Yi Dong, Xian-Hua Wang. (2021) Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein. SENSORS AND ACTUATORS B-CHEMICAL, 330 (129310). [10.1016/j.snb.2020.129310] |
| 12. Yu Luo, Lie Ma. (2020) Bioprosthetic heart valves with reduced immunogenic residuals using vacuum-assisted decellularization treatment. Biomedical Materials, 15 (6): (65012). [PMID:33016260] [10.1088/1748-605X/abaabf] |
| 13. Jie Xing, Ming-Hong Wang, Song Wang, Hai-Lin Cong, You-Qing Shen, Bing Yu. (2020) Analysis of proteins by capillary electrophoresis with a novel diazoresin/β-Cyclodextrin covalent capillary coating method. FERROELECTRICS, [10.1080/00150193.2020.1760608] |
| 14. Qiuyue Sha, Ruixue Guan, Huiying Su, Liang Zhang, Bi-Feng Liu, Zhaoyu Hu, Xin Liu. (2020) Carbohydrate-protein template synthesized high mannose loading gold nanoclusters: A powerful fluorescence probe for sensitive Concanavalin A detection and specific breast cancer cell imaging. TALANTA, 218 (121130). [PMID:32797887] [10.1016/j.talanta.2020.121130] |
| 15. Ying Jia, Han Gao, Mengmeng Tong, Donald M. Anderson. (2019) Cell cycle regulation of the mixotrophic dinoflagellate Dinophysis acuminata: Growth, photosynthetic efficiency and toxin production. HARMFUL ALGAE, 89 (101672). [PMID:31672228] [10.1016/j.hal.2019.101672] |
| 16. Yameng Han, Zhongju Ye, Fuyan Wang, Tianyu Chen, Lin Wei, Langxing Chen, Lehui Xiao. (2019) Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles. Nanoscale, 11 (31): (14793-14801). [PMID:31353389] [10.1039/C9NR01817D] |
| 17. Wei Chen, Min Fu, Xixi Zhu, Qingyun Liu. (2019) A close-packed imprinted colloidal array for naked-eye detection of glycoproteins under physiological pH. BIOSENSORS & BIOELECTRONICS, 142 (111499). [PMID:31306955] [10.1016/j.bios.2019.111499] |
| 18. Yu Luo, Dong Lou, Lie Ma, Changyou Gao. (2019) Optimizing detergent concentration and processing time to balance the decellularization efficiency and properties of bioprosthetic heart valves. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 107 (10): (2235-2243). [PMID:31125175] [10.1002/jbm.a.36732] |
| 19. Manman Han, Wan Li, Rui Chen, Yangyang Han, Xiuhua Liu, Tingting Wang, Huaizhong Guo, Xiaoqiang Qiao. (2018) Amino acid and ionic liquid modified polyhedral oligomeric silsesquioxane-based hybrid monolithic column for high-efficiency capillary liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1572 (82). [PMID:30153983] [10.1016/j.chroma.2018.08.045] |
| 20. Qi-Qing LI, Jian ZHANG, Ji-Hua LIU, Bo-Yang YU. (2018) Morphological and chemical studies of artificial Andrographis paniculata polyploids. Chinese Journal of Natural Medicines, 16 (81). [PMID:29455732] [10.1016/S1875-5364(18)30033-5] |
| 21. Yi Hao, Ruixia Gao, Dechun Liu, Gaiyan He, Yuhai Tang, Zengjun Guo. (2016) A facile and general approach for preparation of glycoprotein-imprinted magnetic nanoparticles with synergistic selectivity. TALANTA, 153 (211). [PMID:27130111] [10.1016/j.talanta.2016.03.005] |
| 22. Yu Tian, Yunfang Li, Jie Mei, Bo Cai, Jinfeng Dong, Zhiguo Shi, Yuxiu Xiao. (2015) Simultaneous separation of acidic and basic proteins using gemini pyrrolidinium surfactants and hexafluoroisopropanol as dynamic coating additives in capillary electrophoresis. JOURNAL OF CHROMATOGRAPHY A, 1412 (151). [PMID:26300480] [10.1016/j.chroma.2015.08.020] |
| 23. Yuanting Xu, Chengcheng Huang, Li Li, Xixun Yu, Xu Wang, Hong Peng, Zhipeng Gu, Yaping Wang. (2013) In vitro enzymatic degradation of a biological tissue fixed by alginate dialdehyde. CARBOHYDRATE POLYMERS, 95 (148). [PMID:23618251] [10.1016/j.carbpol.2013.03.021] |
| 24. Yuanting Xu, Li Li, Hao Wang, Xixun Yu, Zhipeng Gu, Chengcheng Huang, Hong Peng. (2013) In vitro cytocompatibility evaluation of alginate dialdehyde for biological tissue fixation. CARBOHYDRATE POLYMERS, 92 (448). [PMID:23218319] [10.1016/j.carbpol.2012.09.096] |
| 25. Yujie Zhang,Renling Lu,Ming Chen,Shouyong Zhou,Dabing Zhang,Haifeng Han,Mingliang Zhang,Hongdeng Qiu. (2020-08-17) A highly efficient acyl-transfer approach to urea-functionalized silanes and their immobilization onto silica gel as stationary phases for liquid chromatography.. Journal of chromatography. A, 1626 (461366-461366). [PMID:32797845] |
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