页面 2 | Histone Acetyltransferase - 表观遗传学 - 按“信号通路”分类

C646,p300 / CBP HAT抑制剂

规格或纯度 :

≥98%

CAS号 : 328968-36-1 Compound CID : 1285941

分子式: C₂₄H₁₉N₃O₆ 分子量: 445.42

IUPAC Name: 4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid

SMILES: CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)C=C3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C

InChIKey: HEKJYZZSCQBJGB-UNOMPAQXSA-N

InChI: InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12-

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山竹子素

规格或纯度 :

Moligand™

≥95%

CAS号 : 78824-30-3 Compound CID : 5281560

分子式: C₃₈H₅₀O₆ 分子量: 602.8

IUPAC Name: (1S,3Z,5R,7R)-3-[(3,4-dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]bicyclo[3.3.1]nonane-2,4,9-trione

SMILES: CC(=CCC1CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C(C2=O)(C1(C)C)CC=C(C)C)CC(CC=C(C)C)C(=C)C)C

InChIKey: DTTONLKLWRTCAB-BZSUNBQASA-N

InChI: InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3/b32-31-/t27-,28+,37+,38-/m0/s1

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NU 9056,KAT5 / Tip60组蛋白乙酰转移酶抑制剂

规格或纯度 :

≥98%

CAS号 : 1450644-28-6 Compound CID : 72201043

分子式: C₆H₄N₂S₄ 分子量: 232.37

IUPAC Name: 5-(1,2-thiazol-5-yldisulfanyl)-1,2-thiazole

SMILES: C1=C(SN=C1)SSC2=CC=NS2

InChIKey: MLRAMCAHIWHWRM-UHFFFAOYSA-N

InChI: InChI=1S/C6H4N2S4/c1-3-7-9-5(1)11-12-6-2-4-8-10-6/h1-4H

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CTPB,小分子p300 HAT活化剂

规格或纯度 :

≥98%

CAS号 : 586976-24-1 Compound CID : 10311918

分子式: C₃₁H₄₃ClF₃NO₂ 分子量: 554.13

IUPAC Name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecylbenzamide

SMILES: CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OCC)C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F

InChIKey: OYBMVMAXKOGYDC-UHFFFAOYSA-N

InChI: InChI=1S/C31H43ClF3NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-24-19-17-20-28(38-4-2)29(24)30(37)36-25-21-22-27(32)26(23-25)31(33,34)35/h17,19-23H,3-16,18H2,1-2H3,(H,36,37)

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组蛋白乙酰转移酶抑制剂II

规格或纯度 :

≥98%

CAS号 : 932749-62-7 Compound CID : 16203606

分子式: C₂₀H₁₆Br₂O₃ 分子量: 464.15

IUPAC Name: (2E,6E)-2,6-bis[(3-bromo-4-hydroxyphenyl)methylidene]cyclohexan-1-one

SMILES: C1CC(=CC2=CC(=C(C=C2)O)Br)C(=O)C(=CC3=CC(=C(C=C3)O)Br)C1

InChIKey: YOLKEKNTCBWPSD-VOMDNODZSA-N

InChI: InChI=1S/C20H16Br2O3/c21-16-10-12(4-6-18(16)23)8-14-2-1-3-15(20(14)25)9-13-5-7-19(24)17(22)11-13/h4-11,23-24H,1-3H2/b14-8+,15-9+

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Remodelin,N-乙酰基转移酶10（NAT10）抑制剂

规格或纯度 :

Moligand™

≥99%(HPLC)

CAS号 : 949912-58-7 Compound CID : 44442376

分子式: C₁₅H₁₄N₄S 分子量: 282.36

IUPAC Name: 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile

SMILES: C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1

InChIKey: XAEJIFARBQJLML-UHFFFAOYSA-N

InChI: InChI=1S/C15H14N4S/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13/h5-8,10H,1-4H2,(H,17,19)

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4-[O-[(4-甲氧基苯基)磺酰基]肟] -2,6-二甲基-2,5-环己二烯-1,4-二酮

规格或纯度 :

≥96%

CAS号 : 321695-57-2 Compound CID : 2221149

分子式: C₁₅H₁₅NO₅S 分子量: 321.35

IUPAC Name: [(3,5-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] 4-methoxybenzenesulfonate

SMILES: CC1=CC(=NOS(=O)(=O)C2=CC=C(C=C2)OC)C=C(C1=O)C

InChIKey: VEWFTYOFWIXCIO-UHFFFAOYSA-N

InChI: InChI=1S/C15H15NO5S/c1-10-8-12(9-11(2)15(10)17)16-21-22(18,19)14-6-4-13(20-3)5-7-14/h4-9H,1-3H3

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I-CBP 112,CBP / p300 BRD抑制剂

规格或纯度 :

Moligand™

≥98%(HPLC)

CAS号 : 1640282-31-0 Compound CID : 90488984

分子式: C₂₇H₃₆N₂O₅ 分子量: 468.59

IUPAC Name: 1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one

SMILES: CCC(=O)N1CCOC2=C(C1)C=C(C=C2OCC3CCCN(C3)C)C4=CC(=C(C=C4)OC)OC

InChIKey: YKNAKDFZAWQEEO-IBGZPJMESA-N

InChI: InChI=1S/C27H36N2O5/c1-5-26(30)29-11-12-33-27-22(17-29)13-21(20-8-9-23(31-3)24(14-20)32-4)15-25(27)34-18-19-7-6-10-28(2)16-19/h8-9,13-15,19H,5-7,10-12,16-18H2,1-4H3/t19-/m0/s1

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EML 425,CBP / p300抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号 : 1675821-32-5 Compound CID : 91826273

分子式: C₂₇H₂₄N₂O₄ 分子量: 440.49

IUPAC Name: 1,3-dibenzyl-5-[(4-hydroxy-2,6-dimethylphenyl)methylidene]-1,3-diazinane-2,4,6-trione

SMILES: CC1=CC(=CC(=C1C=C2C(=O)N(C(=O)N(C2=O)CC3=CC=CC=C3)CC4=CC=CC=C4)C)O

InChIKey: LUGQBJDYUPNAQQ-UHFFFAOYSA-N

InChI: InChI=1S/C27H24N2O4/c1-18-13-22(30)14-19(2)23(18)15-24-25(31)28(16-20-9-5-3-6-10-20)27(33)29(26(24)32)17-21-11-7-4-8-12-21/h3-15,30H,16-17H2,1-2H3

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A 485,p300 / CBP抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号 : 1889279-16-6 Compound CID : 118958122

分子式: C₂₅H₂₄F₄N₄O₅ 分子量: 536.48

IUPAC Name: N-[(4-fluorophenyl)methyl]-2-[(3R)-6-(methylcarbamoylamino)-2',4'-dioxospiro[1,2-dihydroindene-3,5'-1,3-oxazolidine]-3'-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide

SMILES: CC(C(F)(F)F)N(CC1=CC=C(C=C1)F)C(=O)CN2C(=O)C3(CCC4=C3C=CC(=C4)NC(=O)NC)OC2=O

InChIKey: VRVJKILQRBSEAG-LFPIHBKWSA-N

InChI: InChI=1S/C25H24F4N4O5/c1-14(25(27,28)29)32(12-15-3-5-17(26)6-4-15)20(34)13-33-21(35)24(38-23(33)37)10-9-16-11-18(7-8-19(16)24)31-22(36)30-2/h3-8,11,14H,9-10,12-13H2,1-2H3,(H2,30,31,36)/t14-,24+/m0/s1

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