页面 2 | Sirtuin - 表观遗传学 - 按“信号通路”分类

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非瑟酮

规格或纯度 :

Moligand™

≥96%(HPLC)

CAS号 : 528-48-3 Compound CID : 5281614

分子式: C₁₅H₁₀O₆ 分子量: 286.24

IUPAC Name: 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one

SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O

InChIKey: XHEFDIBZLJXQHF-UHFFFAOYSA-N

InChI: InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

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4-溴白藜芦醇

规格或纯度 :

≥98%(HPLC)

CAS号 : 1224713-90-9 Compound CID : 18475115

分子式: C₁₄H₁₁BrO₂ 分子量: 291.14

IUPAC Name: 5-[(E)-2-(4-bromophenyl)ethenyl]benzene-1,3-diol

SMILES: C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)Br

InChIKey: NCJVLKFAQIWASE-OWOJBTEDSA-N

InChI: InChI=1S/C14H11BrO2/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,16-17H/b2-1+

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7-氯-4-哌嗪-1-基喹啉

规格或纯度 :

≥95%

CAS号 : 837-52-5 Compound CID : 738389

分子式: C₁₃H₁₄ClN₃ 分子量: 247.7

IUPAC Name: 7-chloro-4-piperazin-1-ylquinoline

SMILES: C1CN(CCN1)C2=C3C=CC(=CC3=NC=C2)Cl

InChIKey: DNXNPMDUDGUXOB-UHFFFAOYSA-N

InChI: InChI=1S/C13H14ClN3/c14-10-1-2-11-12(9-10)16-4-3-13(11)17-7-5-15-6-8-17/h1-4,9,15H,5-8H2

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Crocin I

规格或纯度 :

≥98%

CAS号 : 94238-00-3 Compound CID : 5281233

分子式: C44H64O24 分子量: 976.966

IUPAC Name: bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate

SMILES: CC(=CC=CC=C(C)C=CC=C(C)C(=O)OC1C(C(C(C(O1)COC2C(C(C(C(O2)CO)O)O)O)O)O)O)C=CC=C(C)C(=O)OC3C(C(C(C(O3)COC4C(C(C(C(O4)CO)O)O)O)O)O)O

InChIKey: SEBIKDIMAPSUBY-RTJKDTQDSA-N

InChI: InChI=1S/C44H64O24/c1-19(11-7-13-21(3)39(59)67-43-37(57)33(53)29(49)25(65-43)17-61-41-35(55)31(51)27(47)23(15-45)63-41)9-5-6-10-20(2)12-8-14-22(4)40(60)68-44-38(58)34(54)30(50)26(66-44)18-62-42-36(56)32(52)28(48)24(16-46)64-42/h5-14,23-38,41-58H,15-18H2,1-4H3/b6-5+,11-7+,12-8+,19-9+,20-10+,21-13+,22-14+/t23-,24-,25-,26-,27-,28-,29-,30-,31+,32+,33+,34+,35-,36-,37-,38-,41-,42-,43+,44+/m1/s1

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烟酰胺核糖氯化物(NR-CL)

规格或纯度 :

≥98%

CAS号 : 23111-00-4 Compound CID : 90480033

分子式: C₁₁H₁₅N₂O₅Cl 分子量: 290.7

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide;chloride

SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)N.[Cl-]

InChIKey: YABIFCKURFRPPO-IVOJBTPCSA-N

InChI: InChI=1S/C11H14N2O5.ClH/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11;/h1-4,7-9,11,14-16H,5H2,(H-,12,17);1H/t7-,8-,9-,11-;/m1./s1

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培哚普利叔丁胺盐

规格或纯度 :

≥99%

CAS号 : 107133-36-8 Compound CID : 441313

分子式: C₂₃H₄₃N₃O₅ 分子量: 441.6

IUPAC Name: (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine

SMILES: CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N

InChIKey: IYNMDWMQHSMDDE-MHXJNQAMSA-N

InChI: InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1

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1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-b]喹喔啉-2-胺

规格或纯度 :

≥95%

CAS号 : 374922-43-7

分子式: C₂₂H₁₅FN₄O₂S 分子量: 418.44

IUPAC Name: 3-(benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[3,2-b]quinoxalin-2-amine

SMILES: C1=CC=C(C=C1)S(=O)(=O)C2=C(N(C3=NC4=CC=CC=C4N=C23)C5=CC=C(C=C5)F)N

InChIKey: CSFVFDHRYKBBPD-UHFFFAOYSA-N

InChI: InChI=1S/C22H15FN4O2S/c23-14-10-12-15(13-11-14)27-21(24)20(30(28,29)16-6-2-1-3-7-16)19-22(27)26-18-9-5-4-8-17(18)25-19/h1-13H,24H2

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AGK2,sirtuin2（SIRT2）抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 304896-28-4 Compound CID : 2130404

分子式: C₂₃H₁₃Cl₂N₃O₂ 分子量: 434.27

IUPAC Name: (E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-5-ylprop-2-enamide

SMILES: C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N

InChIKey: SVENPFFEMUOOGK-SDNWHVSQSA-N

InChI: InChI=1S/C23H13Cl2N3O2/c24-15-6-8-19(25)18(12-15)22-9-7-16(30-22)11-14(13-26)23(29)28-21-5-1-4-20-17(21)3-2-10-27-20/h1-12H,(H,28,29)/b14-11+

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AGK7,SIRT2抑制剂

规格或纯度 :

≥99%

CAS号 : 304896-21-7 Compound CID : 1372571

分子式: C₂₃H₁₃Cl₂N₃O₂ 分子量: 434.3

IUPAC Name: 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-8-ylprop-2-enamide

SMILES: C1=CC2=C(C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N)N=CC=C2

InChIKey: WRDKBSLEHFRKGG-UHFFFAOYSA-N

InChI: InChI=1S/C23H13Cl2N3O2/c24-16-6-8-19(25)18(12-16)21-9-7-17(30-21)11-15(13-26)23(29)28-20-5-1-3-14-4-2-10-27-22(14)20/h1-12H,(H,28,29)

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AK-7,中枢活性SIRT2抑制剂

规格或纯度 :

≥98%

CAS号 : 420831-40-9 Compound CID : 1328033

分子式: C₁₉H₂₁BrN₂O₃S 分子量: 437.35

IUPAC Name: 3-(azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide

SMILES: C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)Br

InChIKey: IYAYHZZWYNXHEQ-UHFFFAOYSA-N

InChI: InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)

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AK-1,细胞渗透性SIRT2抑制剂

规格或纯度 :

≥98%

CAS号 : 330461-64-8 Compound CID : 1341463

分子式: C₁₉H₂₁N₃O₅S 分子量: 403.45

IUPAC Name: 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide

SMILES: C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]

InChIKey: HAYBKCHPEBZNGW-UHFFFAOYSA-N

InChI: InChI=1S/C19H21N3O5S/c23-19(20-16-8-6-9-17(14-16)22(24)25)15-7-5-10-18(13-15)28(26,27)21-11-3-1-2-4-12-21/h5-10,13-14H,1-4,11-12H2,(H,20,23)

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