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非瑟酮

强力的sirtuin激活化合物（STAC）。植物黄酮醇。
23篇引用文献
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
F156691-250mg
 250mg 现货 Stock Image
F156691-1g
 1g 现货 Stock Image
F156691-5g
 5g 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
Apoptosis (1467) Cell Cycle/DNA Damage (2603) PPAR (156) Sirtuin (94) TNF Receptor (121) Vitamin D Related/Nuclear Receptor (908) 六元杂环化合物 (1702) 苯丙素类 (152) 表观遗传学 (1496)
main product photo

基本描述

别名 漆黄素 | 漆树黄酮 | 紫铆素
英文别名 3,4',7-Tetrahydroxyflavone | 7,3',4'-Trihydroxyflavonol | HY-N0182 | MFCD00006829 | NCGC00095663-01 | 5-Deoxyquercetin | Fustet | UNII-OO2ABO9578 | BIDD:ER0141 | NSC407010 | NSC-407010 | Spectrum5_001797 | BRN 0292829 | C.I. Natural Brown 1 | KBioSS_00167
规格或纯度 Moligand™, ≥96%(HPLC)
英文名称 Fisetin
生化机理 强力的sirtuin激活化合物（STAC）。植物黄酮醇具有多种药理作用。抗炎，抗癌和抗病毒活性。
储存温度 -20°C储存
运输条件 超低温冰袋运输
备注 需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

非瑟酮是一种天然存在的具有治疗活性的黄酮醇，用于合成具有药物活性的抗炎、抗惊厥和抗增殖药物。

AI解读

关联靶点（人）

ALOX12 Tchem 花生四烯酸12-脂氧合酶，12S型(Arachidonate 12-lipoxygenase, 12S-type) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ACHE Tclin 乙酰胆碱酯酶(Acetylcholinesterase) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
DHFR Tclin Dihydrofolate reductase (3072 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TYMS Tclin Thymidylate synthase (1651 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TOP1 Tclin DNA topoisomerase I (7553 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP19A1 Tclin Cytochrome P450 19A1 (6099 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CSNK2A1 Tchem Casein kinase II alpha (3512 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LCK Tclin Tyrosine-protein kinase LCK (9212 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK6 Tclin Cyclin-dependent kinase 6 (1724 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AMY1A Salivary alpha-amylase (100 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIM1 Tchem Serine/threonine-protein kinase PIM1 (9629 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SYK Tclin Tyrosine-protein kinase SYK (7372 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DAPK1 Tchem Death-associated protein kinase 1 (1664 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FASN Tchem Fatty acid synthase (3390 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HBB Tbio Hemoglobin beta chain (329 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CASP1 Tchem Caspase-1 (6235 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TOP2B Tclin DNA topoisomerase II beta (959 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CASP7 Tchem Caspase-7 (3146 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDK1 Tchem Pyruvate dehydrogenase kinase isoform 1 (2021 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A498 (42825 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHN (49357 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DLD-1 (17511 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DMS-273 (14108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
K562 (73714 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KM12 (47707 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
M14 (47487 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF-10A (2462 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MOLT-4 (49676 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
N9 (414 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Glo1 Glyoxalase I (4 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cruzipain (33337 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAL62 Alpha-glucosidase MAL62 (106 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus epidermidis (22802 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pichia kudriavzevii (7448 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Entamoeba histolytica (2676 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nakaseomyces glabratus (9108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida parapsilosis (8521 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida tropicalis (8381 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton rubrum (3646 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Leishmania donovani (89745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypanosoma cruzi (99888 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Oryctolagus cuniculus (11301 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Human immunodeficiency virus 1 (70413 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypanosoma brucei rhodesiense (7991 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Stenotrophomonas maltophilia (1743 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
3T3-L1 (3664 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCRF S-180 (1031 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
J774.A1 (2436 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
L1210 (27553 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BV-2 (3710 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-22 (3261 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
L6 (7924 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Lewis lung carcinoma cell line (1243 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fabG 3-oxoacyl-acyl-carrier protein reductase (70 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fabI Enoyl-acyl-carrier protein reductase (415 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
dengue virus type 2 (2400 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ARG1 Arginase-1 (70 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
E6 Protein E6 (25 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504763367
分子类型 小分子
IUPAC Name 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
INCHI InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChi Key XHEFDIBZLJXQHF-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
Isomeric SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
RTECS LK9250000
PubChem CID 5281614
分子量 286.24
Beilstein号 18221
Reaxy-Rn 292829

化学和物理性质

溶解性 几乎不溶于水；可溶于丙酮、甲醇；微溶于氯仿、苯、乙醚
熔点 330°C
分子量 286.240 g/mol
XLogP3 2.000
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 286.048 Da
单同位素质量Monoisotopic Mass 286.048 Da
拓扑极表面积Topological Polar Surface Area 107.000 Ų
重原子数Heavy Atom Count 21
形式电荷Formal Charge 0
复杂度Complexity 459.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
RTECS LK9250000
Reaxy-Rn 292829
Merck Index 4088

 SDS英文版

技术规格说明书

Purity(HPLC) 96-100（%）
Appearance（F156691) yellow to tan powder
Proton NMR spectrum Conforms to Structure

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到9个结果

批号(Lot Number) 证书类型 日期 货号
D2518315 分析证书 25-04-24 F156691
D2518317 分析证书 25-04-24 F156691
E1704025 分析证书 25-01-20 F156691
K2320339 分析证书 23-11-06 F156691
K2320351 分析证书 23-11-06 F156691
K2320353 分析证书 23-11-06 F156691
J2212249 分析证书 22-03-14 F156691
J2212250 分析证书 22-03-14 F156691
E2311159 分析证书 22-03-14 F156691

此产品的引用文献

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1. Nayun Kim, Junhye Kwon, Ui Sup Shin, Joohee Jung.  (2023)  Fisetin induces the upregulation of AKAP12 mRNA and anti-angiogenesis in a patient-derived organoid xenograft model.  BIOMEDICINE & PHARMACOTHERAPY,  167  (6): (115613).  [PMID:37801904] [10.1016/j.biopha.2023.115613]
2. Fangjie Han, Shulin Luo, Zhifang Wu, Zhishan Liang, Wenxin Yang, Dongxue Han, Zhonghui Sun, Zhenbang Liu, Li Niu.  (2023)  A label-free photoelectrochemical sensor based on BiVO4@graphene oxide hybrid for analysis of the antioxidant capacity in food.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  946  (117713).  [10.1016/j.jelechem.2023.117713]
3. Yufeng Chen, Guobin Xia, Chunfeng Wang, Huawei Wu, Xiaogang Xu, Genxiang Mao, Jiong Wu, Zhenlei Zhao.  (2023)  Impact of dietary plant flavonoids on 7,8-dihydroxyflavone transepithelial transport in human intestinal Caco-2 cells.  Food Science & Nutrition,  [PMID:37970375] [10.1002/fsn3.3581]
4. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu.  (2023)  Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey.  Food Chemistry-X,  19  (100766).  [PMID:37780266] [10.1016/j.fochx.2023.100766]
5. Sichao Gu, Xuefeng Zhou, Xingshi Yuan, Yunliang Zhu, Hui Zhang, Lei Xu, Li Li.  (2023)  Photocurable fisetin silk fibroin hydrogel accelerates infected diabetic wounds healing through biofilm inhibition and macrophage immunomodulation.  MATERIALS LETTERS,  341  (134154).  [10.1016/j.matlet.2023.134154]
6. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng.  (2023)  Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,  196  (210).  [PMID:36724705] [10.1016/j.plaphy.2023.01.050]
7. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li.  (2023)  Stability and antioxidant activity of phenolic compounds during in vitro digestion.  JOURNAL OF FOOD SCIENCE,  88  (2): (696-716).  [PMID:36617678] [10.1111/1750-3841.16440]
8. Hongting Deng, Yuanju He, Hui Cao, Lei Chen, Hui Teng.  (2022)  New insight into the effect of hydroxyl substituted flavonoids on the cytotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline.  Food Frontiers,  4  (1): (289-296).  [10.1002/fft2.194]
9. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo.  (2023)  Chemical composition and anti-inflammatory activities of Castanopsis honey.  Food & Function,  14  (1): (250-261).  [PMID:36484340] [10.1039/D2FO02233H]
10. Xiaochong Song, Qing Luo, Xiaojia Huang.  (2022)  Speciation of organotin compounds in water and seafood samples by online hyphenation of porous polymer-based magnetism-enhanced in-tube solid phase microextraction and HPLC.  ANALYTICA CHIMICA ACTA,  1223  (340175).  [PMID:35998999] [10.1016/j.aca.2022.340175]
11. Ming Guan, Xiaojing Kang, Le Wei, Xingjun Hu, Chao Han, Xing Li, Hanwen Liu, Liang Qu, Zhenwen Zhao.  (2022)  A dual-mode strategy combining SERS with MALDI FTICR MS based on core-shell silver nanoparticles for dye identification and semi-quantification in unearthed silks from Tang Dynasty.  TALANTA,  241  (123277).  [PMID:35121543] [10.1016/j.talanta.2022.123277]
12. Zhang Xiao-Hua, Ma Yi-Xin, Yi Chong, Qing Xiang-Dong, Liu Zhi, Zheng Jing-Jing, Lin Fang, Lv Tian-Feng.  (2020)  Chemometrics-enhanced HPLC–DAD as a rapid and interference-free strategy for simultaneous quantitative analysis of flavonoids in Chinese propolis.  EUROPEAN FOOD RESEARCH AND TECHNOLOGY,  246  (10): (1909-1918).  [10.1007/s00217-020-03543-7]
13. Wei Yang, Zhi-Kai Tian, Hui-Xin Yang, Zhao-Jun Feng, Jian-Mei Sun, Hong Jiang, Chao Cheng, Qing-Lei Ming, Chan-Min Liu.  (2019)  Fisetin improves lead-induced neuroinflammation, apoptosis and synaptic dysfunction in mice associated with the AMPK/SIRT1 and autophagy pathway.  FOOD AND CHEMICAL TOXICOLOGY,  134  (110824).  [PMID:31539617] [10.1016/j.fct.2019.110824]
14. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu.  (2019)  Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies.  Foods,  8  (9): (355).  [PMID:31438605] [10.3390/foods8090355]
15. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Deming Gong.  (2019)  Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity.  Journal of Functional Foods,  58  (1).  [10.1016/j.jff.2019.04.044]
16. Yike Yue, Yongsheng Chen, Sheng Geng, Guizhao Liang, Benguo Liu.  (2018)  Antioxidant and α-Glucosidase Inhibitory Activities of Fisetin.  Natural Product Communications,  [10.1177/1934578X1801301119]
17. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei.  (2018)  Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents.  MOLECULES,  23  (9): (2187).  [PMID:30200208] [10.3390/molecules23092187]
18. Tingting Wang, Huajuan Lin, Qian Tu, Jingjing Liu, Xican Li.  (2016)  Fisetin Protects DNA Against Oxidative Damage and Its Possible Mechanism.  Advanced Pharmaceutical Bulletin,  6  (2): ( 267–270).  [PMID:27478791] [10.15171/apb.2016.037]
19. Xiaodan Liu, Xia Wu.  (2014)  Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles.  RSC Advances,  5  (10): (7433-7439).  [10.1039/C4RA12726A]
20. Zhenning Xu, Mo Wang, Tingting Zhou, Huanshun Yin, Shiyun Ai.  (2013)  Electrochemical biosensing method for the detection of DNA methylation and assay of the methyltransferase activity.  SENSORS AND ACTUATORS B-CHEMICAL,  178  (412).  [10.1016/j.snb.2012.12.124]
21. Huanshun Yin, Zhenning Xu, Mo Wang, Xueping Zhang, Shiyun Ai.  (2013)  An electrochemical biosensor for assay of DNA methyltransferase activity and screening of inhibitor.  ELECTROCHIMICA ACTA,  89  (530).  [10.1016/j.electacta.2012.11.093]
22. Huanshun Yin, Yunlei Zhou, Zhenning Xu, Lijian Chen, Di Zhang, Shiyun Ai.  (2013)  An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein.  BIOSENSORS & BIOELECTRONICS,  41  (492).  [PMID:23021851] [10.1016/j.bios.2012.09.010]
23. Shujuan Xu, Yong Shao, Kun Ma, Qinghua Cui, Guiying Liu, Fei Wu, Minjie Li.  (2011)  Fluorescence light-up recognition of DNA nucleotide based on selective abasic site binding of an excited-state intramolecular proton transfer probe.  ANALYST,  136  (21): (4480-4485).  [PMID:21946800] [10.1039/C1AN15652G]

参考文献

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10. Xiaochong Song, Qing Luo, Xiaojia Huang.  (2022)  Speciation of organotin compounds in water and seafood samples by online hyphenation of porous polymer-based magnetism-enhanced in-tube solid phase microextraction and HPLC.  ANALYTICA CHIMICA ACTA,  1223  (340175).  [PMID:35998999] [10.1016/j.aca.2022.340175]
11. Ming Guan, Xiaojing Kang, Le Wei, Xingjun Hu, Chao Han, Xing Li, Hanwen Liu, Liang Qu, Zhenwen Zhao.  (2022)  A dual-mode strategy combining SERS with MALDI FTICR MS based on core-shell silver nanoparticles for dye identification and semi-quantification in unearthed silks from Tang Dynasty.  TALANTA,  241  (123277).  [PMID:35121543] [10.1016/j.talanta.2022.123277]
12. Zhang Xiao-Hua, Ma Yi-Xin, Yi Chong, Qing Xiang-Dong, Liu Zhi, Zheng Jing-Jing, Lin Fang, Lv Tian-Feng.  (2020)  Chemometrics-enhanced HPLC–DAD as a rapid and interference-free strategy for simultaneous quantitative analysis of flavonoids in Chinese propolis.  EUROPEAN FOOD RESEARCH AND TECHNOLOGY,  246  (10): (1909-1918).  [10.1007/s00217-020-03543-7]
13. Wei Yang, Zhi-Kai Tian, Hui-Xin Yang, Zhao-Jun Feng, Jian-Mei Sun, Hong Jiang, Chao Cheng, Qing-Lei Ming, Chan-Min Liu.  (2019)  Fisetin improves lead-induced neuroinflammation, apoptosis and synaptic dysfunction in mice associated with the AMPK/SIRT1 and autophagy pathway.  FOOD AND CHEMICAL TOXICOLOGY,  134  (110824).  [PMID:31539617] [10.1016/j.fct.2019.110824]
14. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu.  (2019)  Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies.  Foods,  8  (9): (355).  [PMID:31438605] [10.3390/foods8090355]
15. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Deming Gong.  (2019)  Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity.  Journal of Functional Foods,  58  (1).  [10.1016/j.jff.2019.04.044]
16. Yike Yue, Yongsheng Chen, Sheng Geng, Guizhao Liang, Benguo Liu.  (2018)  Antioxidant and α-Glucosidase Inhibitory Activities of Fisetin.  Natural Product Communications,  [10.1177/1934578X1801301119]
17. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei.  (2018)  Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents.  MOLECULES,  23  (9): (2187).  [PMID:30200208] [10.3390/molecules23092187]
18. Tingting Wang, Huajuan Lin, Qian Tu, Jingjing Liu, Xican Li.  (2016)  Fisetin Protects DNA Against Oxidative Damage and Its Possible Mechanism.  Advanced Pharmaceutical Bulletin,  6  (2): ( 267–270).  [PMID:27478791] [10.15171/apb.2016.037]
19. Xiaodan Liu, Xia Wu.  (2014)  Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles.  RSC Advances,  5  (10): (7433-7439).  [10.1039/C4RA12726A]
20. Zhenning Xu, Mo Wang, Tingting Zhou, Huanshun Yin, Shiyun Ai.  (2013)  Electrochemical biosensing method for the detection of DNA methylation and assay of the methyltransferase activity.  SENSORS AND ACTUATORS B-CHEMICAL,  178  (412).  [10.1016/j.snb.2012.12.124]
21. Huanshun Yin, Zhenning Xu, Mo Wang, Xueping Zhang, Shiyun Ai.  (2013)  An electrochemical biosensor for assay of DNA methyltransferase activity and screening of inhibitor.  ELECTROCHIMICA ACTA,  89  (530).  [10.1016/j.electacta.2012.11.093]
22. Huanshun Yin, Yunlei Zhou, Zhenning Xu, Lijian Chen, Di Zhang, Shiyun Ai.  (2013)  An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein.  BIOSENSORS & BIOELECTRONICS,  41  (492).  [PMID:23021851] [10.1016/j.bios.2012.09.010]
23. Shujuan Xu, Yong Shao, Kun Ma, Qinghua Cui, Guiying Liu, Fei Wu, Minjie Li.  (2011)  Fluorescence light-up recognition of DNA nucleotide based on selective abasic site binding of an excited-state intramolecular proton transfer probe.  ANALYST,  136  (21): (4480-4485).  [PMID:21946800] [10.1039/C1AN15652G]

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