自噬 - 按“信号通路”分类 - 小分子和化合物库 | 应用: 蛋白质、肽和寡聚物的聚乙二醇化, PROTAC

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N-棕榈酰-鞘氨醇-1-{琥珀酰[甲氧基(聚乙二醇)2000]}

规格或纯度 :

≥99%

CAS号 : 212116-78-4 Compound CID : 156593866

分子式: C₄₁H₇₇NO₇ 分子量: 696.1

IUPAC Name: 4-O-[(E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-enyl] 1-O-(2-methoxyethyl) butanedioate

SMILES: CCCCCCCCCCCCCCCC(=O)NC(COC(=O)CCC(=O)OCCOC)C(C=CCCCCCCCCCCCCC)O

InChIKey: AVEKIUFLDWAVJR-SJCQXOIGSA-N

InChI: InChI=1S/C41H77NO7/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-38(43)37(36-49-41(46)33-32-40(45)48-35-34-47-3)42-39(44)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h28,30,37-38,43H,4-27,29,31-36H2,1-3H3,(H,42,44)/b30-28+

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PFI-1,BET溴结构域抑制剂

规格或纯度 :

Moligand™

≥98%

CAS号 : 1403764-72-6 Compound CID : 71271629

分子式: C₁₆H₁₇N₃O₄S 分子量: 347.39

IUPAC Name: 2-methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide

SMILES: CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O

InChIKey: TXZPMHLMPKIUGK-UHFFFAOYSA-N

InChI: InChI=1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)

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(+)-JQ1,BET溴结构域抑制剂

规格或纯度 :

≥98%(HPLC)

CAS号 : 1268524-70-4

分子式: C₂₃H₂₅ClN₄O₂S 分子量: 456.99

IUPAC Name: tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate

SMILES: CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C

InChIKey: DNVXATUJJDPFDM-KRWDZBQOSA-N

InChI: InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1

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2-(2,6-二氧代 - 哌啶-3-基)-4-羟基 - 异吲哚-1,3-二酮

规格或纯度 :

≥95%

CAS号 : 5054-59-1 Compound CID : 11778087

分子式: C₁₃H₁₀N₂O₅ 分子量: 274.23

IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O

InChIKey: XMPJICVFSDYOEG-UHFFFAOYSA-N

InChI: InChI=1S/C13H10N2O5/c16-8-3-1-2-6-10(8)13(20)15(12(6)19)7-4-5-9(17)14-11(7)18/h1-3,7,16H,4-5H2,(H,14,17,18)

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Thalidomide-O-COOH

规格或纯度 :

≥98%(HPLC)

CAS号 : 1061605-21-7 Compound CID : 25015436

分子式: C₁₅H₁₂N₂O₇ 分子量: 332.26

IUPAC Name: 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)O

InChIKey: ZVWIXIGBWIEDFO-UHFFFAOYSA-N

InChI: InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)

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泊马度胺 4'-PEG2-胺盐酸盐

规格或纯度 :

≥95%(HPLC)

CAS号 : 2245697-87-2 Compound CID : 134812848

分子式: C₁₉H₂₅ClN₄O₆ 分子量: 440.88

IUPAC Name: 4-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCN.Cl

InChIKey: BIBZEYIXXZHGNZ-UHFFFAOYSA-N

InChI: InChI=1S/C19H24N4O6.ClH/c20-6-8-28-10-11-29-9-7-21-13-3-1-2-12-16(13)19(27)23(18(12)26)14-4-5-15(24)22-17(14)25;/h1-3,14,21H,4-11,20H2,(H,22,24,25);1H

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泊马度胺 4'-PEG1-胺盐酸盐

规格或纯度 :

≥95%(HPLC)

CAS号 : 2154342-56-8 Compound CID : 154828688

分子式: C₁₇H₂₁ClN₄O₅ 分子量: 396.83

IUPAC Name: 4-[2-(2-aminoethoxy)ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCN.Cl

InChIKey: LQYLHZFKGOZTOH-UHFFFAOYSA-N

InChI: InChI=1S/C17H20N4O5.ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23;/h1-3,12,19H,4-9,18H2,(H,20,22,23);1H

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泊马度胺 4'-PEG3-酸

规格或纯度 :

≥95%(HPLC)

CAS号 : 2138440-82-9 Compound CID : 132020335

分子式: C₂₂H₂₇N₃O₉ 分子量: 477.46

IUPAC Name: 3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCC(=O)O

InChIKey: QBYOEHKZQIFBGV-UHFFFAOYSA-N

InChI: InChI=1S/C22H27N3O9/c26-17-5-4-16(20(29)24-17)25-21(30)14-2-1-3-15(19(14)22(25)31)23-7-9-33-11-13-34-12-10-32-8-6-18(27)28/h1-3,16,23H,4-13H2,(H,27,28)(H,24,26,29)

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泊马利度胺4'-烷基C5-胺盐酸盐

规格或纯度 :

≥95%

CAS号 : 2375194-03-7 Compound CID : 139211245

分子式: C₁₈H₂₂N₄O₄.HCl 分子量: 394.86

IUPAC Name: 4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCN.Cl

InChIKey: WJDRWFHGNHTFHU-UHFFFAOYSA-N

InChI: InChI=1S/C18H22N4O4.ClH/c19-9-2-1-3-10-20-12-6-4-5-11-15(12)18(26)22(17(11)25)13-7-8-14(23)21-16(13)24;/h4-6,13,20H,1-3,7-10,19H2,(H,21,23,24);1H

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