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| 描述 | 囊性纤维化跨膜传导调节器 |
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基因和蛋白信息
| 基因ID | 1080 |
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| Uniprot Accession IDs | P13569 Q20BG8 Q20BH2 Q2I0A1 Q2I102 CFTR |
| Ensembl ID | ENSG00000001626 |
| Symbol | ABCC7 CF MRP7 ABC35 ABCC7 CFTR/MRP TNR-CFTR dJ760C5.1 |
| Chromosome | 7 |
| 家族 | Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily. |
| 序列 |
MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFMFYGIFLYLGEVTKAVQPLLLGRIIASYDPDNKEERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLIWELLQASAFCGLGFLIVLALFQAGLGRMMMKYRDQRAGKISERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAAYVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGFGELFEKAKQNNNNRKTSNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAERRNSILTETLHRFSLEGDAPVSWTETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLQMNGIEEDSDEPLERRLSLVPDSEQGEAILPRISVISTGPTLQARRRQSVLNLMTHSVNQGQNIHRKTTASTRKVSLAPQANLTELDIYSRRLSQETGLEISEEINEEDLKECFFDDMESIPAVTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLLGNTPLQDKGNSTHSRNNSYAVIITSTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITVSKILHHKMLHSVLQAPMSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAIAVVAVLQPYIFVATVPVIVAFIMLRAYFLQTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEGKPTKSTKPYKNGQLSKVMIIENSHVKKDDIWPSGGQMTVKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLLNERSLFRQAISPSDRVKLFPHRNSSKCKSKPQIAALKEETEEEVQDTRL
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 463674 | CFTR | cystic fibrosis transmembrane conductance regulator | 9598 | Inparanoid, OMA, EggNOG | |
| Macaque | 574346 | CFTR | cystic fibrosis transmembrane conductance regulator | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 12638 | Cftr | cystic fibrosis transmembrane conductance regulator | 10090 | MGI:88388 | Inparanoid, OMA, EggNOG |
| Rat | 24255 | Cftr | cystic fibrosis transmembrane conductance regulator | 10116 | RGD:2332 | Inparanoid, OMA |
| Dog | 492302 | CFTR | cystic fibrosis transmembrane conductance regulator | 9615 | VGNC:39180 | Inparanoid, OMA, EggNOG |
| Horse | 100071259 | CFTR | cystic fibrosis transmembrane conductance regulator | 9796 | VGNC:16468 | Inparanoid, OMA, EggNOG |
| Cow | 281067 | CFTR | cystic fibrosis transmembrane conductance regulator | 9913 | VGNC:50053 | Inparanoid, OMA, EggNOG |
| Pig | 403154 | CFTR | cystic fibrosis transmembrane conductance regulator | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100014119 | CFTR | cystic fibrosis transmembrane conductance regulator | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100559531 | cftr | cystic fibrosis transmembrane conductance regulator | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100486085 | cftr | cystic fibrosis transmembrane conductance regulator | 8364 | XB-GENE-853972 | Inparanoid, OMA, EggNOG |
| Zebrafish | 559080 | cftr | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 7955 | ZDB-GENE-050517-20 | Inparanoid, OMA, EggNOG |
蛋白质类别
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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