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| 描述 | 丝氨酸/苏氨酸蛋白激酶 mTOR |
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基因和蛋白信息
| 基因ID | 2475 |
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| Uniprot Accession IDs | P42345 Q4LE76 Q5TER1 Q6LE87 Q96QG3 Q9Y4I3 |
| Ensembl ID | ENSG00000198793 |
| Symbol | FRAP FRAP1 FRAP2 RAFT1 RAPT1 SKS FRAP FRAP1 FRAP2 RAFT1 RAPT1 |
| Chromosome | 1 |
| 家族 | Belongs to the PI3/PI4-kinase family. |
| 序列 |
MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 457945 | MTOR | mechanistic target of rapamycin kinase | 9598 | VGNC:8416 | OMA, EggNOG |
| Macaque | 106992736 | MTOR | mechanistic target of rapamycin kinase | 9544 | OMA, EggNOG | |
| Mouse | 56717 | Mtor | mechanistic target of rapamycin kinase | 10090 | MGI:1928394 | Inparanoid, OMA, EggNOG |
| Rat | 56718 | Mtor | mechanistic target of rapamycin kinase | 10116 | RGD:68371 | Inparanoid, OMA, EggNOG |
| Dog | 478232 | MTOR | mechanistic target of rapamycin kinase | 9615 | VGNC:43490 | Inparanoid, OMA, EggNOG |
| Horse | 100051341 | MTOR | mechanistic target of rapamycin kinase | 9796 | VGNC:20434 | Inparanoid, OMA, EggNOG |
| Cow | 100139219 | MTOR | mechanistic target of rapamycin kinase | 9913 | VGNC:31748 | Inparanoid, OMA, EggNOG |
| Pig | 100127359 | MTOR | mechanistic target of rapamycin kinase | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100619675 | MTOR | mechanistic target of rapamycin kinase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 419455 | MTOR | mechanistic target of rapamycin | 9031 | CGNC:2430 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100565267 | mtor | mechanistic target of rapamycin kinase | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | XB-GENE-994583 | Putative ortholog of fKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (MTOR), 1 of 2 [Source:Xenbase;Acc:XB-GENE-994583] | 8364 | OMA, EggNOG | ||
| Zebrafish | 324254 | mtor | mechanistic target of rapamycin kinase | 7955 | ZDB-GENE-030131-2974 | Inparanoid, OMA, EggNOG |
| C. elegans | 172167 | let-363 | Target of rapamycin homolog | 6239 | Inparanoid, OMA | |
| Fruitfly | 47396 | Tor | Target of rapamycin | 7227 | FBgn0021796 | Inparanoid, EggNOG |
| S.cerevisiae | 853632 | TOR2 | phosphatidylinositol kinase-related protein kinase TOR2 | 4932 | S000001686 | Inparanoid, OMA |
| S.cerevisiae | 853529 | TOR1 | phosphatidylinositol kinase-related protein kinase TOR1 | 4932 | S000003827 | OMA, EggNOG |
蛋白质类别
PANTHER Classes
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / protein kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / nucleotide kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / transferase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / nucleic acid binding / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / non-receptor serine/threonine protein kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / protein kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / nucleotide kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / transferase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / kinase / 丝氨酸/苏氨酸蛋白激酶mtor
蛋白质 / nucleic acid binding / 丝氨酸/苏氨酸蛋白激酶mtor
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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