基本描述

英文别名	SCHEMBL886921 \| .delta.-Vitamin E \| Indapamide Impurity \| UNII-JU84X1II0N \| 8-Methyltocol \| Tox21_111941_1 \| 4-amino-5-(ethanesulfonyl)-2-methoxybenzoic acid \| DELTA-TOCOPHEROL [WHO-DD] \| s6348 \| .delta.-Tocopherol \| HY-113026 \| NCGC00160622-01 \| [2R[2R*(
规格或纯度	≥90%
英文名称	(+)-δ-Tocopherol
生化机理	生育酚（TCP）（维生素 E）是一系列（α、β、γ 和 δ）手性有机分子，它们在色醇环的苯酚分子甲基化程度上各不相同。生育酚是一种脂溶性抗氧化剂，可保护细胞膜免受氧化损伤。α-生育酚是被人类优先吸收的生育酚形式。生育酚的各种异构体和类似物在体内具有对立和不同的调节活性。
储存温度	2-8°C储存,充氩
运输条件	冰袋运输

AI解读

关联靶点（人）

LMNA Tbio Prelamin-A/C (36751 活性数据)

点击查看靶蛋白信息： LMNA

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 活性数据)

点击查看靶蛋白信息： PMP22

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

rep Replicase polyprotein 1ab (378 活性数据)

点击查看靶蛋白信息： rep

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488186681
EC号	204-299-0
分子类型	小分子
IUPAC Name	(2R)-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol
INCHI	InChI=1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3/t21-,22-,27-/m1/s1
InChi Key	GZIFEOYASATJEH-VHFRWLAGSA-N
Canonical SMILES	CC1=CC(=CC2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)O
Isomeric SMILES	CC1=CC(=CC2=C1O[C@](CC2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O
WGK Germany	3
PubChem CID	92094
分子量	402.65

化学和物理性质

密度	0.935
分子量	402.700 g/mol
XLogP3	10.000
氢键供体数Hydrogen Bond Donor Count	1
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	12
精确质量Exact Mass	402.35 Da
单同位素质量Monoisotopic Mass	402.35 Da
拓扑极表面积Topological Polar Surface Area	29.500 Å²
重原子数Heavy Atom Count	29
形式电荷Formal Charge	0
复杂度Complexity	448.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	3
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

SDS英文版

技术规格说明书

Purity(HPLC)	90-100
Proton NMR spectrum	Conforms to Structure
Appearance(T109349)	Yellow to Brown liquid

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到8个结果

批号(Lot Number)	证书类型	日期	货号
E2323972	分析证书	25-01-22	T109349
E2323976	分析证书	25-01-22	T109349
E2323978	分析证书	25-01-22	T109349
E23231155	分析证书	25-01-22	T109349
G2216609	分析证书	24-04-07	T109349
G2216632	分析证书	24-04-07	T109349
D2424427	分析证书	24-03-08	T109349
C2031139	分析证书	22-01-26	T109349

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Pan Gao, Yunpeng Ding, Zhe Chen, Zhangtao Zhou, Wu Zhong, Chuanrong Hu, Dongping He, Xingguo Wang. (2022) Characteristics and Antioxidant Activity of Walnut Oil Using Various Pretreatment and Processing Technologies. Foods, 11 (12): (1698). [PMID:35741896] [10.3390/foods11121698]
2. Zihan Xu, Shanshan Liu, Mingyue Shen, Jianhua Xie, Jun Yang. (2022) Evaluation of trans fatty acids, carbonyl compounds and bioactive minor components in commercial linseed oils. FOOD CHEMISTRY, 369 (130930). [PMID:34469834] [10.1016/j.foodchem.2021.130930]
3. Wenjiang Dong, Qiyu Chen, Changqing Wei, Rongsuo Hu, Yuzhou Long, Ying Zong, Zhong Chu. (2021) Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity. ULTRASONICS SONOCHEMISTRY, 74 (105578). [PMID:33965776] [10.1016/j.ultsonch.2021.105578]
4. Liu Shanshan, Hu Huiyu, Yu Yanpeng, Zhao Jiahui, Liu Lichun, Zhao Shanshan, Xie Jianhua, Li Chang, Shen Mingyue. (2021) Simultaneous Determination of Tocopherols, Phytosterols, and Squalene in Vegetable Oils by High Performance Liquid Chromatography-Tandem Mass Spectrometry. Food Analytical Methods, 14 (8): (1567-1576). [10.1007/s12161-021-01987-5]
5. Mingyi Yang, Zisheng Luo, Sunan Gao, Tarun Belwal, Lei Wang, Ming Qi, Zhaojun Ban, Bin Wu, Fengzhong Wang, Li Li. (2021) The chemical composition and potential role of epicuticular and intracuticular wax in four cultivars of table grapes. POSTHARVEST BIOLOGY AND TECHNOLOGY, 173 (111430). [10.1016/j.postharvbio.2020.111430]
6. Liangliang Zhang, Chenyu Liu, Fugui Li, Weihong Qiao. (2020) Performance Improvement of Cleaning Formulations for the Exterior Surface of High-Speed Trains. JOURNAL OF SURFACTANTS AND DETERGENTS, 24 (1): (99-109). [10.1002/jsde.12464]
7. Cheng-wei Yu, Qi-rui Hu, Hao-wei Wang, Ze-yuan Deng. (2020) Comparison of 11 rice bran stabilization methods by analyzing lipase activities. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 44 (4): (e14370). [10.1111/jfpp.14370]

参考文献

1. Sontag TJ, Parker RS. (2002) Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status.. J Biol Chem, 277 (28): (25290-6). [PMID:11997390] [10.1021/op500134e]
2. K S Epler,R G Ziegler,N E Craft. (1993-09-08) Liquid chromatographic method for the determination of carotenoids, retinoids and tocopherols in human serum and in food.. Journal of chromatography, 619 ((1)): (37-48). [PMID:8245162]
3. K S Sharpless,D L Duewer. (1995-12-01) Population distributions and intralaboratory reproducibility for fat-soluble vitamin-related compounds in human serum.. Analytical chemistry, 67 ((23)): (4416-4422). [PMID:8633780]
4. R Brigelius-Flohé,M G Traber. (1999-07-01) Vitamin E: function and metabolism.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 13 ((10)): (1145-1155). [PMID:10385606]
5. F P Cappuccio,E Rink,L Perkins-Porras,C McKay,S Hilton,A Steptoe. (2003-05-30) Estimation of fruit and vegetable intake using a two-item dietary questionnaire: a potential tool for primary health care workers.. Nutrition, metabolism, and cardiovascular diseases : NMCD, 13 ((1)): (12-19). [PMID:12772433]
6. Alain Mavon,Véronique Raufast,Daniel Redoulès. (2004-11-17) Skin absorption and metabolism of a new vitamin E prodrug, delta-tocopherol-glucoside: in vitro evaluation in human skin models.. Journal of controlled release : official journal of the Controlled Release Society, 100 ((2)): (221-231). [PMID:15544870]
7. Qing Jiang,Jeffrey Wong,Henrik Fyrst,Julie D Saba,Bruce N Ames. (2004-12-15) gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.. Proceedings of the National Academy of Sciences of the United States of America, 101 ((51)): (17825-17830). [PMID:15596715]
8. Chandan K Sen,Savita Khanna,Sashwati Roy. (2005-03-09) Tocotrienol: the natural vitamin E to defend the nervous system?. Annals of the New York Academy of Sciences, 1031 (127-142). [PMID:15753140]
9. Christian P Fischer,Natalie J Hiscock,Samar Basu,Bengt Vessby,Anders Kallner,Lars-Börje Sjöberg,Mark A Febbraio,Bente K Pedersen. (2005-12-31) Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humans.. Journal of applied physiology (Bethesda, Md. : 1985), 100 ((5)): (1679-1687). [PMID:16384840]
10. Michael W Clarke,Natalie C Ward,Jason H Y Wu,Jonathan M Hodgson,Ian B Puddey,Kevin D Croft. (2006-01-10) Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes.. The American journal of clinical nutrition, 83 ((1)): (95-102). [PMID:16400056]
11. Jana Cela,Caren Chang,Sergi Munné-Bosch. (2011-07-02) Accumulation of γ- rather than α-tocopherol alters ethylene signaling gene expression in the vte4 mutant of Arabidopsis thaliana.. Plant & cell physiology, 52 ((8)): (1389-1400). [PMID:21719428]
12. Yun Wang,Michelle Moreland,James G Wagner,Bruce N Ames,Beate Illek,David B Peden,Qing Jiang. (2011-07-19) Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells.. The Journal of nutritional biochemistry, 23 ((6)): (602-608). [PMID:21764283]
13. Xiaofeng Fang, Gaozhan Zhao, Su Zhang, Yaoxi Li, Hanqing Gu, Yan Li, Qiao Zhao, Yijun Qi,. (2019-01-01) Chloroplast-to-Nucleus Signaling Regulates MicroRNA Biogenesis in Arabidopsis.. Developmental cell, 48 ((3)): ( 371-382 ). [PMID:30595534]
14. Kirill Gorshkov,Manisha Pradhan,Miao Xu,Shu Yang,Emily M Lee,Catherine Z Chen,Min Shen,Wei Zheng. (2020-06-14) Cell-Based No-Wash Fluorescence Assays for Compound Screens Using a Fluorescence Cytometry Plate Reader.. The Journal of pharmacology and experimental therapeutics, 374 ((3)): (500-511). [PMID:32532853]
15. M G Traber,H J Kayden. (1987-09-01) Tocopherol distribution and intracellular localization in human adipose tissue.. The American journal of clinical nutrition, 46 ((3)): (488-495). [PMID:3630967]
16. Meilin Liu,Agneta Wallmon,Caroline Olsson-Mortlock,Rolf Wallin,Tom Saldeen. (2003-02-26) Mixed tocopherols inhibit platelet aggregation in humans: potential mechanisms.. The American journal of clinical nutrition, 77 ((3)): (700-706). [PMID:12600864]
17. Siro Passi,Ornella De Pità,Mauro Grandinetti,Cristina Simotti,Gian Paolo Littarru. (2003-12-30) The combined use of oral and topical lipophilic antioxidants increases their levels both in sebum and stratum corneum.. BioFactors (Oxford, England), 18 ((1-4)): (289-297). [PMID:14695946]
18. Jacqueline Limpens,Fritz H Schröder,Corrina M A de Ridder,Cindy A Bolder,Mark F Wildhagen,Ute C Obermüller-Jevic,Klaus Krämer,Wytske M van Weerden. (2006-04-15) Combined lycopene and vitamin E treatment suppresses the growth of PC-346C human prostate cancer cells in nude mice.. The Journal of nutrition, 136 ((5)): (1287-1293). [PMID:16614418]
19. Gabor Oláh,Katalin Módis,Domokos Gero,Kunihiro Suzuki,Douglas Dewitt,Daniel L Traber,Csaba Szabó. (2011-08-09) Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells.. International journal of molecular medicine, 28 ((5)): (711-720). [PMID:21822532]
20. Amanda K Smolarek,Nanjoo Suh. (2012-01-19) Chemopreventive activity of vitamin E in breast cancer: a focus on γ- and δ-tocopherol.. Nutrients, 3 ((11)): (962-986). [PMID:22254089]
21. Laura L Baxter,Juan J Marugan,Jingbo Xiao,Art Incao,John C McKew,Wei Zheng,William J Pavan. (2012-07-24) Plasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice.. Nutrients, 4 ((6)): (467-490). [PMID:22822447]
22. Pan Gao, Yunpeng Ding, Zhe Chen, Zhangtao Zhou, Wu Zhong, Chuanrong Hu, Dongping He, Xingguo Wang. (2022) Characteristics and Antioxidant Activity of Walnut Oil Using Various Pretreatment and Processing Technologies. Foods, 11 (12): (1698). [PMID:35741896] [10.3390/foods11121698]
23. Zihan Xu, Shanshan Liu, Mingyue Shen, Jianhua Xie, Jun Yang. (2022) Evaluation of trans fatty acids, carbonyl compounds and bioactive minor components in commercial linseed oils. FOOD CHEMISTRY, 369 (130930). [PMID:34469834] [10.1016/j.foodchem.2021.130930]
24. Wenjiang Dong, Qiyu Chen, Changqing Wei, Rongsuo Hu, Yuzhou Long, Ying Zong, Zhong Chu. (2021) Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity. ULTRASONICS SONOCHEMISTRY, 74 (105578). [PMID:33965776] [10.1016/j.ultsonch.2021.105578]
25. Liu Shanshan, Hu Huiyu, Yu Yanpeng, Zhao Jiahui, Liu Lichun, Zhao Shanshan, Xie Jianhua, Li Chang, Shen Mingyue. (2021) Simultaneous Determination of Tocopherols, Phytosterols, and Squalene in Vegetable Oils by High Performance Liquid Chromatography-Tandem Mass Spectrometry. Food Analytical Methods, 14 (8): (1567-1576). [10.1007/s12161-021-01987-5]
26. Mingyi Yang, Zisheng Luo, Sunan Gao, Tarun Belwal, Lei Wang, Ming Qi, Zhaojun Ban, Bin Wu, Fengzhong Wang, Li Li. (2021) The chemical composition and potential role of epicuticular and intracuticular wax in four cultivars of table grapes. POSTHARVEST BIOLOGY AND TECHNOLOGY, 173 (111430). [10.1016/j.postharvbio.2020.111430]
27. Liangliang Zhang, Chenyu Liu, Fugui Li, Weihong Qiao. (2020) Performance Improvement of Cleaning Formulations for the Exterior Surface of High-Speed Trains. JOURNAL OF SURFACTANTS AND DETERGENTS, 24 (1): (99-109). [10.1002/jsde.12464]
28. Cheng-wei Yu, Qi-rui Hu, Hao-wei Wang, Ze-yuan Deng. (2020) Comparison of 11 rice bran stabilization methods by analyzing lipase activities. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 44 (4): (e14370). [10.1111/jfpp.14370]

溶液计算器

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
T109349-200mg	200mg	期货
T109349-1g	1g	现货
T109349-5g	5g	现货

(+)-δ-生育酚

库存信息

库存信息

库存信息

基本描述

AI解读

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器