6-硫鸟嘌呤, DNA 抑制剂

抗代谢药。鸟嘌呤类似物。
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货号 (SKU) 包装规格 是否现货 价格 数量
T106639-200mg
200mg 期货 Stock Image
T106639-1g
1g 现货 Stock Image
T106639-5g
5g 现货 Stock Image
T106639-25g
25g 期货 Stock Image

基本描述

别名 2-氨基-6-巯基嘌呤 | 6-硫代鸟嘌呤
英文别名 Tioguanin | Tioguanina [INN-Spanish] | THG | WIX31ZPX66 | 2-Amino 6MP | SMR000857244 | Thioguanine2-Amino-6-purinethiol | Tioguaninum [INN-Latin] | DX4 | MLS001333131 | 2-Amino-1,7-dihydro-6H-purin-6-thion | 2-Amino-1,7-dihydro-6H-purin-6-thion [Czech] |
规格或纯度 Moligand™, ≥98%
英文名称 6-Thioguanine
生化机理 用于治疗白血病的抗代谢药。与次黄嘌呤和鸟嘌呤竞争次黄嘌呤-鸟嘌呤磷酸核糖转移酶,该酶催化生成嘌呤核苷酸的关键步骤。它与天然嘌呤碱基通过相同的途径进行核糖基化和磷酸化;作为核苷酸,它能抑制核酸合成过程中的各种细胞过程。抗代谢药。鸟嘌呤类似物。可结合到线粒体 DNA 中,诱导 DNA 双链断裂。在体内具有抗肿瘤、免疫抑制和抗炎作用。硫唑嘌呤的代谢产物。
应用 抗肿瘤。
运输条件 常规运输
作用类型 抑制剂
作用机制 DNA 抑制剂
备注 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。
产品介绍

6-Thioguanine is a chemotherapy drμg that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.抗肿瘤。

6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
An immunosuppressive, anti-neoplastic, and anti-cancer

AI解读

产品属性

ALogP -0.1

关联靶点(人)

PTGS1 Tclin 前列腺素 G/H 合酶 1(Prostaglandin G/H synthase 1) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IMPDH2 Tclin 肌苷-5'-单磷酸脱氢酶2(Inosine-5'-monophosphate dehydrogenase 2) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IMPDH1 Tclin 肌苷-5'-单磷酸脱氢酶1(Inosine-5'-monophosphate dehydrogenase 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TYR Tclin Tyrosinase (717 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Sigmar1 Sigma opioid receptor (160 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cckar Cholecystokinin A receptor (90 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Helicobacter pylori (3113 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHO (4503 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EMT6 (738 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
J774.A1 (2436 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
L1210 (27553 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P388/ADR (1216 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
B16-F10 (4610 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ddn Putative uncharacterized protein (49 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Bacillus anthracis (2936 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (110 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Glra2 Glycine receptor (1745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Vero C1008 (1716 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504760785
EC号 205-827-2
分子类型 小分子
IUPAC Name 2-amino-3,7-dihydropurine-6-thione
INCHI InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
InChi Key WYWHKKSPHMUBEB-UHFFFAOYSA-N
Canonical SMILES C1=NC2=C(N1)C(=S)N=C(N2)N
Isomeric SMILES C1=NC2=C(N1)C(=S)N=C(N2)N
WGK Germany 3
RTECS UP0740000
PubChem CID 2723601
UN Number 2811
Packing Group I
分子量 167.19
Beilstein号 157765
Reaxy-Rn 1074099

化学和物理性质

溶解性 Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.
熔点 360°C
分子量 167.190 g/mol
XLogP3 -0.100
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 2
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 167.027 Da
单同位素质量Monoisotopic Mass 167.027 Da
拓扑极表面积Topological Polar Surface Area 111.000 Ų
重原子数Heavy Atom Count 11
形式电荷Formal Charge 0
复杂度Complexity 225.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

象形图 GHS06,   GHS08
信号词 Danger
危险声明

H301: 吞咽会中毒

H341: 怀疑引起遗传缺陷

预防措施声明

P321: 特殊处理(请参阅此标签上的...)。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P281: 根据需要使用个人防护设备。

P270: 使用本产品时,请勿进食、饮水或吸烟。

P330: 漱口

P203: 使用前,获取、阅读并遵守所有安全说明。

P301+P316: 如果吞咽:立即寻求紧急医疗救助。

P318: 如果暴露或担心,请就医。

WGK Germany 3
RTECS UP0740000
Reaxy-Rn 1074099
Class 6.1
Merck Index 9337
个人防护装备 Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges

技术规格说明书

Purity(HPLC) 98-100(%)
Appearance(T106639) White to Yellow-Green Powder
Solubility in 1 M NaOH,Colorless to Light Green,Clear to Hazy,50 mg/ml pass
Infrared spectrum Conforms to Structure
Carbon by Elemental Analysis 35.15-36.65(%)
Nitrogen by Elemental Analysis 41.00-42.75(%)

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找到5个结果

批号(Lot Number) 证书类型 日期 货号
I2411122 分析证书 24-06-13 T106639
I2411123 分析证书 24-06-13 T106639
E2304284 分析证书 21-05-17 T106639
E2304289 分析证书 21-05-17 T106639
F2307318 分析证书 21-05-17 T106639

相关技术文章

FAQ
肿瘤细胞中核苷酸的合成
Nucleotide Synthesis in Cancer Cells

此产品的引用文献

1. Jia Wang, Deyue Yan, Wei Huang.  (2022)  A fluorescence zinc metal-organic framework for the effective detection of Fe3+ and Fe2+ in water.  INORGANIC CHEMISTRY COMMUNICATIONS,  138  (109282).  [10.1016/j.inoche.2022.109282]
2. Yu Zhang, Xin Xu, Bing Yan.  (2022)  A multicolor-switchable fluorescent lanthanide MOFs triggered by anti-cancer drugs: multifunctional platform for anti-cancer drug sensing and information anticounterfeiting.  Journal of Materials Chemistry C,  10  (9): (3576-3584).  [10.1039/D1TC05935A]
3. Bingyong Lin, Yueliang Wang, Yuanyuan Yao, Lifen Chen, Yanbo Zeng, Lei Li, Zhenyu Lin, Longhua Guo.  (2021)  Oil-Free Gold Nanobipyramid@Ag Microgels as a Functional SERS Substrate for Direct Detection of Small Molecules in a Complex Sample Matrix.  ANALYTICAL CHEMISTRY,  93  (49): (16727–16733).  [PMID:34851090] [10.1021/acs.analchem.1c04797]
4. Wen-Shu Zhang, Ya-Ning Wang, Yue Wang, Zhang-Run Xu.  (2019)  Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system.  SENSORS AND ACTUATORS B-CHEMICAL,  283  (532).  [10.1016/j.snb.2018.12.077]
5. Shuai Yue, Xiao-Ting Sun, Yue Wang, Wen-Shu Zhang, Zhang-Run Xu.  (2018)  Microparticles with size/charge selectivity and pH response for SERS monitoring of 6-thioguanine in blood serum.  SENSORS AND ACTUATORS B-CHEMICAL,  273  (1539).  [10.1016/j.snb.2018.07.062]
6. Junling Duan, Yuanhong Zhang, Yanbin Yin, Houshen Li, Jun Wang, Lusheng Zhu.  (2018)  A novel “on-off-on” fluorescent sensor for 6-thioguanine and Hg2+ based on g-C3N4 nanosheets.  SENSORS AND ACTUATORS B-CHEMICAL,  257  (504).  [10.1016/j.snb.2017.10.071]
7. Jingjie Cui, Jing Chen, Shaowei Chen, Li Gao, Ping Xu, Hong Li.  (2016)  Au/TiO2 nanobelt heterostructures for the detection of cancer cells and anticancer drug activity by potential sensing.  NANOTECHNOLOGY,  27  (9): (95603).  [PMID:26822679] [10.1088/0957-4484/27/9/095603]
8. Hongli Li, Xiaoli Chong, Yufeng Chen, Lei Yang, Lan Luo, Bing Zhao, Yuan Tian.  (2016)  Detection of 6-Thioguanine by surface-enhanced Raman scattering spectroscopy using silver nanoparticles-coated silicon wafer.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  493  (52).  [10.1016/j.colsurfa.2016.01.032]
9. Xu Wang, Ziqiang Tan, Yuanhu Pan, Awais Ihsan, Qianying Liu, Lingli Huang, Guyue Cheng, Dongmei Chen, Yanfei Tao, Zhenli Liu, Zonghui Yuan.  (2015)  Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies.  JOURNAL OF APPLIED TOXICOLOGY,  35  (11): (1415-1426).  [PMID:25663419] [10.1002/jat.3107]

参考文献

1. Moreau AC, Paul S, Del Tedesco E, Rinaudo-Gaujous M, Boukhadra N, Genin C, Peyrin-Biroulet L, Roblin X.  (2014)  Association between 6-thioguanine nucleotides levels and clinical remission in inflammatory disease: a meta-analysis..  Inflamm Bowel Dis,  20  (3): (464-71).  [PMID:24418904] [10.1021/op500134e]
2. Jia Wang, Deyue Yan, Wei Huang.  (2022)  A fluorescence zinc metal-organic framework for the effective detection of Fe3+ and Fe2+ in water.  INORGANIC CHEMISTRY COMMUNICATIONS,  138  (109282).  [10.1016/j.inoche.2022.109282]
3. Yu Zhang, Xin Xu, Bing Yan.  (2022)  A multicolor-switchable fluorescent lanthanide MOFs triggered by anti-cancer drugs: multifunctional platform for anti-cancer drug sensing and information anticounterfeiting.  Journal of Materials Chemistry C,  10  (9): (3576-3584).  [10.1039/D1TC05935A]
4. Bingyong Lin, Yueliang Wang, Yuanyuan Yao, Lifen Chen, Yanbo Zeng, Lei Li, Zhenyu Lin, Longhua Guo.  (2021)  Oil-Free Gold Nanobipyramid@Ag Microgels as a Functional SERS Substrate for Direct Detection of Small Molecules in a Complex Sample Matrix.  ANALYTICAL CHEMISTRY,  93  (49): (16727–16733).  [PMID:34851090] [10.1021/acs.analchem.1c04797]
5. Wen-Shu Zhang, Ya-Ning Wang, Yue Wang, Zhang-Run Xu.  (2019)  Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system.  SENSORS AND ACTUATORS B-CHEMICAL,  283  (532).  [10.1016/j.snb.2018.12.077]
6. Shuai Yue, Xiao-Ting Sun, Yue Wang, Wen-Shu Zhang, Zhang-Run Xu.  (2018)  Microparticles with size/charge selectivity and pH response for SERS monitoring of 6-thioguanine in blood serum.  SENSORS AND ACTUATORS B-CHEMICAL,  273  (1539).  [10.1016/j.snb.2018.07.062]
7. Junling Duan, Yuanhong Zhang, Yanbin Yin, Houshen Li, Jun Wang, Lusheng Zhu.  (2018)  A novel “on-off-on” fluorescent sensor for 6-thioguanine and Hg2+ based on g-C3N4 nanosheets.  SENSORS AND ACTUATORS B-CHEMICAL,  257  (504).  [10.1016/j.snb.2017.10.071]
8. Jingjie Cui, Jing Chen, Shaowei Chen, Li Gao, Ping Xu, Hong Li.  (2016)  Au/TiO2 nanobelt heterostructures for the detection of cancer cells and anticancer drug activity by potential sensing.  NANOTECHNOLOGY,  27  (9): (95603).  [PMID:26822679] [10.1088/0957-4484/27/9/095603]
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