3,3′,5,5′-四甲基联苯胺二盐酸盐

36篇引用文献

无水级

≥98%

CAS编号: 64285-73-0
分子式: C₁₆H₂₀N₂·2HCl
分子量: 313.27
EC号: 264-769-6
MDL号: MFCD00012961
PubChem编号: 174033

有货

库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
T105329-1g	1g	期货
T105329-5g	5g	现货
T105329-25g	25g	现货

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基本描述

英文别名	4-(4-amino-3,5-dimethylphenyl)-2,6-dimethylaniline dihydrochloride \| AC-24636 \| BCP31645 \| 4-(4-amino-3,5-dimethylphenyl)-2,6-dimethylaniline;dihydrochloride \| 3,3',5,5'-Tetramethylbenzidine dihydrochloride \| TMB (dihydrochloride hydrate) \| SCHEMBL472235
规格或纯度	无水级, ≥98%
英文名称	3,3′,5,5′-Tetramethylbenzidine dihydrochloride
生化机理	3,3',5,5'-四甲基联苯胺二盐酸盐是 3,3′,5,5′-四甲基联苯胺（TMB）的盐类。3,3′,5,5′-四甲基联苯胺（TMB）是一种过氧化物酶底物，适用于 ELISA 程序，可产生可溶性的弯曲产物，通常呈淡蓝色，在 370 或 620-650 纳米波长下具有分光光度活性。加入 2M H2SO4 后，底物活性停止，在 450 纳米波长下读数。
应用	A peroxidase substrate suitable for use in ELISA procedures.
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	过氧化氢酶的底物，用于酶免ELISA反应。该底物能产生一种可溶性淡黄色的末端产物，能在370 或 620-650 nm处光度法读取. TMB反应可用 2 M H₂SO₄ 终止(结果为黄色),并能在450 nm读取。二氨基联苯的非制癌替代物。 CAS 号: 64285-73-0(无水物） CAS 号: 207738-08-7（水合物） A peroxidase substrate suitable for use in ELISA procedures. 苯胺的非致癌性替代品。 A peroxidase substrate suitable for use in ELISA procedures.

名称和识别符

EC号	264-769-6
IUPAC Name	4-(4-amino-3,5-dimethylphenyl)-2,6-dimethylaniline;dihydrochloride
INCHI	InChI=1S/C16H20N2.2ClH/c1-9-5-13(6-10(2)15(9)17)14-7-11(3)16(18)12(4)8-14;;/h5-8H,17-18H2,1-4H3;2*1H
InChi Key	NYNRGZULARUZCC-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=CC(=C1N)C)C2=CC(=C(C(=C2)C)N)C.Cl.Cl
Isomeric SMILES	CC1=CC(=CC(=C1N)C)C2=CC(=C(C(=C2)C)N)C.Cl.Cl
WGK Germany	3
PubChem CID	174033
分子量	313.27

化学和物理性质

密度	0.892
敏感性	对空气、湿度和光线敏感
熔点	≥300°C
分子量	313.300 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	4
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	312.116 Da
单同位素质量Monoisotopic Mass	312.116 Da
拓扑极表面积Topological Polar Surface Area	52.000 Å²
重原子数Heavy Atom Count	20
形式电荷Formal Charge	0
复杂度Complexity	226.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	3

安全和危险性（GHS）

象形图	GHS08, GHS07
信号词	Warning
危险声明	H341: 怀疑引起遗传缺陷 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。 P317: 寻求紧急医疗救助。
WGK Germany	3
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

SDS英文版

技术规格说明书

Purity(HPLC)	98-100（%）
Water by Karl Fischer	0-1（%）
Purity(Titration by AgNO3)	98-100（%）
Appearance（T105329)	white to light brown powder or crystals
Proton NMR spectrum	Conforms to Structure
Solubility in AcOH/H2O (1/2)	Clear to slightly hazy yellow to green,at 20mg/ml

技术规格说明书

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找到6个结果

批号(Lot Number)	证书类型	日期	货号
L2405053	分析证书	23-04-17	T105329
D23011055	分析证书	23-04-17	T105329
D23011061	分析证书	23-04-17	T105329
D23011062	分析证书	23-04-17	T105329
F2406052	分析证书	23-04-17	T105329
G2404050	分析证书	23-04-17	T105329

此产品的引用文献

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2. Yuting Wang, Tong Li, Hui Wei. (2023) Determination of the Maximum Velocity of a Peroxidase-like Nanozyme. ANALYTICAL CHEMISTRY, 95 (26): (10105–10109). [PMID:37341651] [10.1021/acs.analchem.3c01830]
3. Ran Tang, Xiaoyu Yuan, Zhi Jia, Fang Yang, Gang Ye, Jie Liu. (2023) Ruthenium Dioxide Nanoparticles Treat Alzheimer’s Disease by Inhibiting Oxidative Stress and Alleviating Neuroinflammation. ACS Applied Nano Materials, [10.1021/acsanm.3c01650]
4. Wenxiang Du, Weijian Chen, Jing Wang, Hongjie Zhang, Lei Song, Yuan Hu, Xiaopeng Ma. (2023) A dual-nanozyme-loaded black phosphorus multifunctional therapeutic platform for combined photothermal/photodynamic/starvation cancer therapy. Journal of Materials Chemistry B, 11 (23): (5185-5194). [PMID:37264903] [10.1039/D3TB00372H]
5. Yuyun Ye, Hongli Yu, Bohan Chen, Yifan Zhao, Bai Lv, Guanghe Xue, Yong Sun, Jie Cao. (2023) Engineering nanoenzymes integrating Iron-based metal organic frameworks with Pt nanoparticles for enhanced Photodynamic-Ferroptosis therapy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 645 (882). [PMID:37178565] [10.1016/j.jcis.2023.05.003]
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7. Shunmei Li, Jie Xiang, Fang Yang, Ruo Yuan, Yun Xiang. (2023) Aptamer/proximity hybridization-based label-free and highly sensitive colorimetric detection of methotrexate via polymerization/nicking recycling amplifications. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 295 (122633). [PMID:36965245] [10.1016/j.saa.2023.122633]
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9. Li Zhang, Wendong Zhang, Yao Nie, Yi Wang, Pu Zhang. (2023) Covalent organic framework-supported ultrasmall Rh nanoparticles as peroxidase mimics for colorimetric sensing of cysteine. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 636 (568). [PMID:36669450] [10.1016/j.jcis.2023.01.020]
10. Zhenyu Ding, Zhe Li, Xiaoxue Zhao, Yanrong Miao, Zhenfeng Yuan, Yuanyuan Jiang, Yizhong Lu. (2023) Self-deposited ultrasmall Ru nanoparticles on carbon nitride with high peroxidase-mimicking activity for the colorimetric detection of alkaline phosphatase. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 631 (86). [PMID:36368217] [10.1016/j.jcis.2022.11.001]
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参考文献

1. Shiyue Wu, Chaoqin Han, Wensheng Fu, Xue Gong, Zhongwei Jiang, Yi Wang, Pu Zhang. (2023) Smartphone-enabled colorimetric determination of silver ions exploiting the peroxidase-mimetic behavior of bowl-shaped Pd3Pt nanocrystals. MICROCHEMICAL JOURNAL, 195 (109434). [PMID:27152988] [10.1016/j.microc.2023.109434]
2. Yuting Wang, Tong Li, Hui Wei. (2023) Determination of the Maximum Velocity of a Peroxidase-like Nanozyme. ANALYTICAL CHEMISTRY, 95 (26): (10105–10109). [PMID:37341651] [10.1021/acs.analchem.3c01830]
3. Ran Tang, Xiaoyu Yuan, Zhi Jia, Fang Yang, Gang Ye, Jie Liu. (2023) Ruthenium Dioxide Nanoparticles Treat Alzheimer’s Disease by Inhibiting Oxidative Stress and Alleviating Neuroinflammation. ACS Applied Nano Materials, [10.1021/acsanm.3c01650]
4. Wenxiang Du, Weijian Chen, Jing Wang, Hongjie Zhang, Lei Song, Yuan Hu, Xiaopeng Ma. (2023) A dual-nanozyme-loaded black phosphorus multifunctional therapeutic platform for combined photothermal/photodynamic/starvation cancer therapy. Journal of Materials Chemistry B, 11 (23): (5185-5194). [PMID:37264903] [10.1039/D3TB00372H]
5. Yuyun Ye, Hongli Yu, Bohan Chen, Yifan Zhao, Bai Lv, Guanghe Xue, Yong Sun, Jie Cao. (2023) Engineering nanoenzymes integrating Iron-based metal organic frameworks with Pt nanoparticles for enhanced Photodynamic-Ferroptosis therapy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 645 (882). [PMID:37178565] [10.1016/j.jcis.2023.05.003]
6. Zhijun Huang, Xiaoting Li, Yanting Feng, Yonghui Tian, Yixiang Duan. (2023) Sensitive visual detection of gram-positive bacteria by composite filter membrane combined with antibiotic modified nanoparticles. SENSORS AND ACTUATORS B-CHEMICAL, 387 (133817). [10.1016/j.snb.2023.133817]
7. Shunmei Li, Jie Xiang, Fang Yang, Ruo Yuan, Yun Xiang. (2023) Aptamer/proximity hybridization-based label-free and highly sensitive colorimetric detection of methotrexate via polymerization/nicking recycling amplifications. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 295 (122633). [PMID:36965245] [10.1016/j.saa.2023.122633]
8. Qi Xu, Han Hu, Zhimin Mo, Tianyou Chen, Qianyuan He, Zushun Xu. (2023) A multifunctional nanotheranostic agent based on Lenvatinib for multimodal synergistic hepatocellular carcinoma therapy with remarkably enhanced efficacy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 638 (375). [PMID:36746055] [10.1016/j.jcis.2023.01.144]
9. Li Zhang, Wendong Zhang, Yao Nie, Yi Wang, Pu Zhang. (2023) Covalent organic framework-supported ultrasmall Rh nanoparticles as peroxidase mimics for colorimetric sensing of cysteine. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 636 (568). [PMID:36669450] [10.1016/j.jcis.2023.01.020]
10. Zhenyu Ding, Zhe Li, Xiaoxue Zhao, Yanrong Miao, Zhenfeng Yuan, Yuanyuan Jiang, Yizhong Lu. (2023) Self-deposited ultrasmall Ru nanoparticles on carbon nitride with high peroxidase-mimicking activity for the colorimetric detection of alkaline phosphatase. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 631 (86). [PMID:36368217] [10.1016/j.jcis.2022.11.001]
11. Yutong Li, Xinhui Gu, Jiayin Zhao, Fengna Xi. (2022) Fabrication of a Ratiometric Fluorescence Sensor Based on Carbon Dots as Both Luminophores and Nanozymes for the Sensitive Detection of Hydrogen Peroxide. MOLECULES, 27 (21): (7379). [PMID:36364206] [10.3390/molecules27217379]
12. Jie Xiang, Junyi Zhang, Shunmei Li, Ruo Yuan, Yun Xiang. (2022) Aptamer-based and sensitive label-free colorimetric sensing of phenylalanine via cascaded signal amplifications. ANALYTICA CHIMICA ACTA, 1230 (340393). [PMID:36192064] [10.1016/j.aca.2022.340393]
13. Yuan Yuni, liu Wei, Liu Qi, He Qing, Hu Yuyang, Jiang Xinyu, Chen Xiaoqing. (2022) A dual-channel probe based on copper ion-mediated metal organic framework composite for colorimetric and ratiometric fluorescence monitoring of glyphosate degradation in soil and water. MICROCHIMICA ACTA, 189 (10): (1-10). [PMID:36066687] [10.1007/s00604-022-05473-5]
14. Peilei Liu, Penghao Ji, Liping Wang, Haiyan Guo, Minfeng Huo, Jianlin Shi. (2022) Concurrent antibiosis and anti-inflammation against bacterial pneumonia by zinc hexacyanoferrate nanocatalysts. BIOMATERIALS, 289 (121768). [PMID:36088676] [10.1016/j.biomaterials.2022.121768]
15. Shuoying Huang, Wenqiang Lai, Bingqian Liu, Mingdi Xu, Junyang Zhuang, Dianping Tang, Youxiu Lin. (2023) Colorimetric and photothermal dual-mode immunoassay of aflatoxin B1 based on peroxidase-like activity of Pt supported on nitrogen-doped carbon. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 284 (121782). [PMID:36049298] [10.1016/j.saa.2022.121782]
16. Yaqian He, Mengxue Yang, Tao Wang, Liuyang Xu, Zhenhe Ma, Jian Mu, Desong Wang, Dawei Gao. (2022) Regulation of Interstitial Fluid Pressure for Improved Intratumor Drug Permeability and Nanozyme-Enhanced Chemocatalytic Therapy. ACS Sustainable Chemistry & Engineering, 10 (27): (8908–8918). [10.1021/acssuschemeng.2c02129]
17. Xiaoyan Gan, Feng Qiu, Ruo Yuan, Yun Xiang. (2022) Biobarcode and sequence-responsive DNA nanocapsules for label-free and sensitive electrochemical detection of circulating tumor cells. SENSORS AND ACTUATORS B-CHEMICAL, 368 (132207). [10.1016/j.snb.2022.132207]
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溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

3,3′,5,5′-四甲基联苯胺 二盐酸盐

库存信息

库存信息

库存信息

基本描述

名称和识别符

化学和物理性质

安全和危险性（GHS）

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

3,3′,5,5′-四甲基联苯胺二盐酸盐