基本信息

产品名称	Pertuzumab (anti-HER2), erb-b2 受体酪氨酸激酶 2 抗体
别名	帕妥珠单抗（抗 HER2）
英文别名	2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, [R-(R,S)]- \| Q27078025 \| (2R,3S)-3-(isopropylamino)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]butan-2-ol \| DTXSID401118341 \| SCHEMBL8027938 \| (2R,3S)-1-[(7-methyl-2,3-dih
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	ERBB2/HER2/CD340
应用	ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse)
偶联	Unconjugated
作用类型	抑制剂
作用机制	erb-b2 受体酪氨酸激酶 2 抗体

AI解读

产品属性

抗体类型	Primary antibody
克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	145.44 kDa
纯化方法	Protein A purified
纯度	>95%
来源	CHO supernatant
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	380610-27-5
分子类型	抗体

图片

Flow Cytometry: Pertuzumab (anti-HER2) (P412000)

Pertuzumab (anti-HER2) (P412000) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling HER2 (red) with Pertuzumab (anti-HER2) (P412000). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Pertuzumab (anti-HER2) (P412000)

Pertuzumab (anti-HER2) (P412000) - SEC
The purity of Pertuzumab (anti-HER2) (P412000) is more than 95% verified by HPLC.

ELISA: Pertuzumab (anti-HER2) (P412000)

Pertuzumab (anti-HER2) (P412000) - ELISA
Immobilized HER2-23-652-his at 2 μg/mL can bind Pertuzumab (anti-HER2) (P412000) with the EC₅₀ of 13.75 ng/mL.

关联靶点（人）

CYP1A2 Tchem 细胞色素 P450 1A2(Cytochrome P450 1A2) (1 活性数据)

点击查看靶蛋白信息： CYP1A2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

ERBB2 Tclin 受体酪氨酸蛋白激酶 erbB-2(Receptor tyrosine-protein kinase erbB-2) (0 活性数据)

点击查看靶蛋白信息： ERBB2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

ADRB2 Tclin β-2肾上腺素受体(Beta-2 adrenergic receptor) (2 活性数据)

点击查看靶蛋白信息： ADRB2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 活性数据)

点击查看靶蛋白信息： ERBB2

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERBB2 Tclin Epidermal growth factor receptor and ErbB2 (HER1 and HER2) (186 活性数据)

点击查看靶蛋白信息： ERBB2

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERBB2 Tclin Epidermal growth factor receptor (487 活性数据)

点击查看靶蛋白信息： ERBB2

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERBB2 Tclin FASN/HER2 (2 活性数据)

点击查看靶蛋白信息： ERBB2

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

安全和危险性（GHS）

SDS英文版

技术规格说明书

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到4个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F1215935	分析证书	24-12-24	P412000
ZJ24F1215934	分析证书	24-12-24	P412000
ZJ23F0800951	分析证书	23-09-04	P412000
ZJ23F0800952	分析证书	23-09-04	P412000

可替换产品

参考文献

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溶液计算器

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
P412000-100μg	100μg	现货
P412000-1mg	1mg	现货
P412000-5mg	5mg	现货
P412000-10mg	10mg	期货

Pertuzumab (anti-HER2), erb-b2 受体酪氨酸激酶 2 抗体

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溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

Pertuzumab (anti-HER2), erb-b2 受体酪氨酸激酶 2 抗体

库存信息

库存信息

库存信息

库存信息

基本信息

AI解读

产品属性

图片

关联靶点（人）

作用机制

安全和危险性（GHS）

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关技术文章

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参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器