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依布硒, 抗氧化剂

硒有机化合物，抗氧化剂，谷胱甘肽过氧化物酶的模拟物
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货号 (SKU) 包装规格 是否现货 价格 数量
P137293-5mg
 5mg 现货 Stock Image
P137293-25mg
 25mg 现货 Stock Image
P137293-100mg
 100mg 现货 Stock Image
P137293-500mg
 500mg 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
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基本描述

别名 2-苯基-1,2-苯并异硒唑-3(2H)-酮
英文别名 Ebselen, cysteine modifier | HMS502P13 | Lopac-E-3520 | Prestwick0_000740 | SCHEMBL33829 | C042986 | NCGC00024072-04 | CID3194 | AC-1124 | BPBio1_000770 | Bio2_000542 | 2-phenyl-1,2-benzoselenazol-3-one | BSPBio_002538 | HMS1791D04 | NCGC00015412-01 | BSP
规格或纯度 Moligand™, ≥98%
英文名称 Ebselen
生化机理 一种具有抗氧化特性的有机硒化合物。在没有硫醇基团的情况下，它能抑制哺乳动物的脂氧合酶，还能通过与半胱氨酸残基的相互作用抑制谷胱甘肽 S 转移酶和木瓜蛋白酶。硒-有机化合物，抗氧化剂，谷胱甘肽过氧化物酶的模拟物。抑制脂氧合酶、NO 合酶、NADPH 氧化酶、蛋白激酶 C 和 H+/K(+)-ATP 酶，产生抗炎作用。
应用 An inhibitor of 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase.
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
作用机制 抗氧化剂
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO.An inhibitor of 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase.

Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO.
An inhibitor of 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase.


application：

Ebselen has been used as a:voltage-dependent calcium channels (VDCCs) blocker；glutathione peroxidase mimetic to test its inhibitory effect on contraction-mediated deoxy glucose (2-DG) uptake in mouse；extensor digitorum longus (fast-twitch) muscle

glucocerebrosidase inhibitor；hepatitis C virus helicase inhibitor

AI解读

关联靶点（人）

EHMT2 Tchem 组蛋白赖氨酸N-甲基转移酶EHMT2(Histone-lysine N-methyltransferase EHMT2) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
EHMT1 Tchem 组蛋白赖氨酸N-甲基转移酶EHMT1(Histone-lysine N-methyltransferase EHMT1) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IDE Tchem 胰岛素降解酶(Insulin-degrading enzyme) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
EPHX2 Tchem 双功能环氧化物水解酶2(Bifunctional epoxide hydrolase 2) (3 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
GALE Tchem UDP-葡萄糖4-表异构酶(UDP-glucose 4-epimerase) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PMM2 Tchem 磷酸甘露糖变位酶2(Phosphomannomutase 2) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PHOSPHO1 Tchem 磷酸乙醇胺/磷酸胆碱磷酸酶(Phosphoethanolamine/phosphocholine phosphatase) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
MPI Tchem 甘露糖-6-磷酸异构酶(Mannose-6-phosphate isomerase) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
MIF Tchem 巨噬细胞移动抑制因子(Macrophage migration inhibitory factor) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
BBOX1 Tchem γ-丁甜菜碱双加氧酶(Gamma-butyrobetaine dioxygenase) (5 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IDO1 Tchem 吲哚胺2,3-双加氧酶1(Indoleamine 2,3-dioxygenase 1) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
VDR Tclin Vitamin D receptor (26531 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
IGF1R Tclin Insulin-like growth factor I receptor (8605 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ANPEP Tchem Aminopeptidase N (863 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MIF Tchem Macrophage migration inhibitory factor (979 活性数据)
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POLB Tchem DNA polymerase beta (23632 活性数据)
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TRPV1 Tclin Vanilloid receptor (8273 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FGFR1 Tclin Fibroblast growth factor receptor 1 (9149 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDOA Tbio Fructose-bisphosphate aldolase A (1 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SRC Tclin Tyrosine-protein kinase SRC (10310 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALB Tchem Serum albumin (2651 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
METAP2 Tchem Methionine aminopeptidase 2 (1512 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RPS6KA4 Tchem Ribosomal protein S6 kinase alpha 4 (2104 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIM1 Tchem Serine/threonine-protein kinase PIM1 (9629 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SYK Tclin Tyrosine-protein kinase SYK (7372 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HDAC3 Tclin Histone deacetylase 3 (3654 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTK2 Tclin Focal adhesion kinase 1 (4730 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HK1 Tchem Hexokinase type I (266 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MTOR Tclin Serine/threonine-protein kinase mTOR (13850 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MET Tclin Hepatocyte growth factor receptor (10718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PRKCA Tchem Protein kinase C alpha (5923 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EPHX2 Tchem Epoxide hydratase (3844 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FYN Tclin Tyrosine-protein kinase FYN (5308 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HDAC9 Tclin Histone deacetylase 9 (708 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LYN Tclin Tyrosine-protein kinase Lyn (4251 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MPI Tchem Mannose-6-phosphate isomerase (940 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

ampC Beta-lactamase AmpC (62480 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cruzipain (33337 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
polC DNA polymerase III (243 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac5 Histone deacetylase 5 (5 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Streptococcus (3973 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterococcus (1748 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterobacter cloacae (7976 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus epidermidis (22802 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Citrobacter freundii (1864 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella oxytoca (929 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Morganella morganii (1291 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterococcus faecium (13803 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Listeria monocytogenes (2626 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mycobacterium tuberculosis (203094 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterococcus faecalis (29875 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mycolicibacterium smegmatis (8003 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypanosoma brucei (78846 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Bos taurus (956 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Gerbillinae (442 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Human immunodeficiency virus 1 (70413 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Salmonella enterica (1497 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Streptococcus sp. 'group A' (3417 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHO (4503 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHO-K1 (1115 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-22 (3261 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Murine-murine hybridoma (mark 3) (19 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferase (58 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TRXR Thioredoxin reductase (20 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Npsr1 Neuropeptide S receptor (260 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PYK Pyruvate kinase (6726 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
botA Botulinum neurotoxin type A (1303 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504750646
分子类型 小分子
IUPAC Name 2-phenyl-1,2-benzoselenazol-3-one
INCHI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChi Key DYEFUKCXAQOFHX-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
Isomeric SMILES C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
WGK Germany 3
PubChem CID 3194
分子量 274.18

化学和物理性质

溶解性 Solubility in water: insoluble Solubility in other solvents: soluble in methanol, ethanol, THF, ethyl acetate, DMSO
敏感性 对热敏感；对空气敏感
熔点 183 °C
分子量 274.190 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 1
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 274.985 Da
单同位素质量Monoisotopic Mass 274.985 Da
拓扑极表面积Topological Polar Surface Area 20.300 Ų
重原子数Heavy Atom Count 16
形式电荷Formal Charge 0
复杂度Complexity 275.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS06,   GHS08,   GHS09
信号词 Danger
危险声明

H301: 吞咽会中毒

H331: 吸入会中毒

H373: 通过长时间或反复暴露对器官造成损害

H400: 对水生生物有剧毒

H410: 对水生生物有剧毒并具有长期持续影响
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P273: 避免释放到环境中。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P271: 仅在室外或通风良好的地方使用。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P391: 收集溢出物

P330: 漱口

P301+P316: 如果吞咽：立即寻求紧急医疗救助。

P316: 立即寻求紧急医疗救助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
Merck Index 3486

 SDS英文版

技术规格说明书

Carbon by Elemental Analysis 56.45-57.45（%）
Nitrogen by Elemental Analysis 4.6-5.6（%）
Melting point 176-185（℃）
Appearance（P137293) White or light yellow powder
NMR (Solvent) CD3OD Identity by NMR Consistent
Solubility in CHCL3，Faint Yellow to Yellow Clear(20 mg/ml) pass
Purity(HPLC) 98-100（%）

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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批号(Lot Number) 证书类型 日期 货号
E2512458 分析证书 25-02-20 P137293
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I2403193 分析证书 24-08-07 P137293
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H2219272 分析证书 24-06-20 P137293
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如何在您的发表作品中引用阿拉丁的产品和网站?
1. Minglu Li, Hui Han, Shengmei Song, Shaomin Shuang, Chuan Dong.  (2021)  AIE-based fluorescent boronate probe and its application in peroxynitrite imaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  261  (120044).  [PMID:34118522] [10.1016/j.saa.2021.120044]
2. Yiming Li, Guanhui Chen, Yi He, Xiliu Zhang, Binghui Zeng, Chao Wang, Chen Yi, Dongsheng Yu.  (2019)  Ebselen rescues oxidative-stress-suppressed osteogenic differentiation of bone-marrow-derived mesenchymal stem cells via an antioxidant effect and the PI3K/Akt pathway.  JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY,  55  (64).  [PMID:31345368] [10.1016/j.jtemb.2019.06.002]

参考文献

1. Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J et al..  (2020)  Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors..  Br J Pharmacol,  177  (8): (1898-1916).  [PMID:31881095] [10.1021/op500134e]
2. Adeosun SO et al..  (2018)  A Novel Fluorescence-Based Assay for the Measurement of Biliverdin Reductase Activity..  React Oxyg Species (Apex),  5  (13): (35-45).  [PMID:29379885]
3. Poser SW et al..  (2019)  Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery..  FASEB J,  33  (8): (9235-9249).  [PMID:31145643]
4. Minglu Li, Hui Han, Shengmei Song, Shaomin Shuang, Chuan Dong.  (2021)  AIE-based fluorescent boronate probe and its application in peroxynitrite imaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  261  (120044).  [PMID:34118522] [10.1016/j.saa.2021.120044]
5. Yiming Li, Guanhui Chen, Yi He, Xiliu Zhang, Binghui Zeng, Chao Wang, Chen Yi, Dongsheng Yu.  (2019)  Ebselen rescues oxidative-stress-suppressed osteogenic differentiation of bone-marrow-derived mesenchymal stem cells via an antioxidant effect and the PI3K/Akt pathway.  JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY,  55  (64).  [PMID:31345368] [10.1016/j.jtemb.2019.06.002]

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