L-甲硫氨酰甘氨酸

  • ≥98%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
M121443-100mg
100mg 现货 Stock Image
M121443-500mg
500mg 现货 Stock Image
M121443-1g
1g 现货 Stock Image
M121443-5g
5g 现货 Stock Image
M121443-25g
25g 期货 Stock Image
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多肽 (97)

基本描述

别名 L-甲硫氨酰甘氨酸
英文别名 DS-14534 | AKOS010405233 | CHEBI:73611 | L-Methionylglycine | L-Methionyl-glycine | EN300-881949 | NSC19173 | QXOHLNCNYLGICT-YFKPBYRVSA-N | 5-Chloroisatoic anhydride, 97% | 2-[[(2S)-2-Azaniumyl-4-methylsulfanylbutanoyl]amino]acetate | L-Methionylglycine (
规格或纯度 ≥98%
英文名称 L-Methionylglycine
储存温度 -20°C储存
运输条件 超低温冰袋运输

AI解读

关联靶点(人)

ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

GAP1 General amino-acid permease GAP1 (481 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504764437
EC号 238-487-9
分子类型 小分子
IUPAC Name 2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]acetic acid
INCHI InChI=1S/C7H14N2O3S/c1-13-3-2-5(8)7(12)9-4-6(10)11/h5H,2-4,8H2,1H3,(H,9,12)(H,10,11)/t5-/m0/s1
InChi Key QXOHLNCNYLGICT-YFKPBYRVSA-N
Canonical SMILES CSCCC(C(=O)NCC(=O)O)N
Isomeric SMILES CSCC[C@@H](C(=O)NCC(=O)O)N
WGK Germany 3
PubChem CID 6992930
分子量 206.26
Reaxy-Rn 1726610

化学和物理性质

比旋光度 +85 +/- 2 (C=2,In water at 25°C )
熔点 212°C(lit.)
分子量 206.270 g/mol
XLogP3 -3.000
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 206.073 Da
单同位素质量Monoisotopic Mass 206.073 Da
拓扑极表面积Topological Polar Surface Area 118.000 Ų
重原子数Heavy Atom Count 13
形式电荷Formal Charge 0
复杂度Complexity 187.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
Reaxy-Rn 1726610

技术规格说明书

Purity(HPLC) 98-100(%)
Specific Rotation [a]20/D(c=2 in H2O) 83-90(°)
Nitrogen by Elemental Analysis 13.2-13.9(%)
Carbon by Elemental Analysis 39.7-41.8(%)
Appearance(M121443) white powder
Identity (MS) Conforms to structure
Solubility,Colorless and clear(5% in H2O) pass
Proton NMR spectrum Conforms to structure

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到5个结果

批号(Lot Number) 证书类型 日期 货号
B2208360 分析证书 22-01-13 M121443
B2208362 分析证书 22-01-13 M121443
B2208364 分析证书 22-01-13 M121443
B2208436 分析证书 22-01-13 M121443
B2208447 分析证书 22-01-13 M121443

参考文献

1. M Q McCollum,K E Webb.  (1998-11-14)  Glycyl-L-sarcosine absorption across ovine omasal epithelium during coincubation with other peptide substrates and volatile fatty acids..  Journal of animal science,  76  ((10)): (2706-2711).  [PMID:9814913]
2. Yue-Hua Dou,Ning Bao,Jing-Juan Xu,Hong-Yuan Chen.  (2002-11-02)  A dynamically modified microfluidic poly(dimethylsiloxane) chip with electrochemical detection for biological analysis..  Electrophoresis,  23  ((20)): (3558-3566).  [PMID:12412125]
3. Olga B Morozova,Sergey E Korchak,Hans-Martin Vieth,Alexandra V Yurkovskaya.  (2009-05-15)  Photo-CIDNP study of transient radicals of Met-Gly and Gly-Met peptides in aqueous solution at variable pH..  The journal of physical chemistry. B,  113  ((20)): (7398-7406).  [PMID:19438284]
4. Urszula Rychlewska,Beata Warzajtis,Biljana D Glisic,Snezana Rajkovic,Milos Djuran.  (2010-02-04)  Crystallographic evidence of Gly-D,L-Met oxidation to its sulfoxide in the presence of gold(III): solid solution of the racemic mixture of two diastereoisomers..  Acta crystallographica. Section C, Crystal structure communications,  66  ((Pt 2)): (m51-m54).  [PMID:20124681]
5. Justin Kai-Chi Lau,Seydina Lo,Junfang Zhao,K W Michael Siu,Alan C Hopkinson.  (2013-02-27)  Fragmentation chemistry of [Met-Gly]•+, [Gly-Met]•+, and [Met-Met]•+ radical cations..  Journal of the American Society for Mass Spectrometry,  24  ((4)): (543-553).  [PMID:23440718]
6. Katherine A Glass,Jarrett M Link,Jonathan M Brunger,Franklin T Moutos,Charles A Gersbach,Farshid Guilak.  (2014-04-29)  Tissue-engineered cartilage with inducible and tunable immunomodulatory properties..  Biomaterials,  35  ((22)): (5921-5931).  [PMID:24767790]
7. Snežana Rajković,Beata Warżajtis,Marija D Živković,Biljana Đ Glišić,Urszula Rychlewska,Miloš I Djuran.  (2018-06-02)  Hydrolysis of Methionine- and Histidine-Containing Peptides Promoted by Dinuclear Platinum(II) Complexes with Benzodiazines as Bridging Ligands: Influence of Ligand Structure on the Catalytic Ability of Platinum(II) Complexes..  Bioinorganic chemistry and applications,  2018  (3294948-3294948).  [PMID:29853829]
8. J C Matthews,K E Webb.  (1995-11-01)  Absorption of L-carnosine, L-methionine, and L-methionylglycine by isolated sheep ruminal and omasal epithelial tissue..  Journal of animal science,  73  ((11)): (3464-3475).  [PMID:8586607]
9. Lin Zheng,Hongzhu Dong,Guowan Su,Qiangzhong Zhao,Mouming Zhao.  (2015-12-01)  Radical scavenging activities of Tyr-, Trp-, Cys- and Met-Gly and their protective effects against AAPH-induced oxidative damage in human erythrocytes..  Food chemistry,  197  ((Pt A)): (807-813).  [PMID:26617020]
10. Marija D Živković,Snežana Rajković,Biljana Đ Glišić,Nenad S Drašković,Miloš I Djuran.  (2017-05-02)  Hydrolysis of the amide bond in histidine- and methionine-containing dipeptides promoted by pyrazine and pyridazine palladium(II)-aqua dimers: Comparative study with platinum(II) analogues..  Bioorganic chemistry,  72  (190-198).  [PMID:28460361]

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