2'-甲氧基胞苷

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货号 (SKU)	包装规格	是否现货
M119522-250mg	250mg	现货
M119522-1g	1g	现货
M119522-5g	5g	期货

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Anti-infection (2825) HCV (160) Nucleosides (90) 六元杂环化合物 (1702) 嘧啶类 (541)

基本描述

英文别名	DS-14587 \| 2'-O-Methylcytidine \| 2'-O-METHYL-CYTIDINE \| 4-Amino-1-((2R,3R,4S,5R)-4-hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one \| 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-tetrahydrofuran-2-yl]pyrimidin-
规格或纯度	≥98%(HPLC)
英文名称	2′-O-Methylcytidine
储存温度	2-8°C储存
运输条件	冰袋运输

Hepatitis C virus (23859 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

PubChem SID	504757343
分子类型	小分子
IUPAC Name	4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
INCHI	InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChi Key	RFCQJGFZUQFYRF-ZOQUXTDFSA-N
Canonical SMILES	COC1C(C(OC1N2C=CC(=NC2=O)N)CO)O
Isomeric SMILES	CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O
WGK Germany	3
PubChem CID	150971
分子量	257.24
Reaxy-Rn	619844

溶解性	微溶于水
敏感性	对热敏感
比旋光度	72° (C=1,H2O)
熔点	257 °C
分子量	257.240 g/mol
XLogP3	-1.600
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	5
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	257.101 Da
单同位素质量Monoisotopic Mass	257.101 Da
拓扑极表面积Topological Polar Surface Area	118.000 Å²
重原子数Heavy Atom Count	18
形式电荷Formal Charge	0
复杂度Complexity	397.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	4
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

WGK Germany	3
Reaxy-Rn	619844
个人防护装备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Specific Rotation [a]20/D(c=1 in H2O)	70-74（°）
Melting point	251-259（℃）
Purity(HPLC)	98-100（%）
Appearance（M119522)	White or off-white powder or crystals
Infrared spectrum	Conforms to Structure
Proton NMR spectrum	Conforms to structure

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找到3个结果

批号(Lot Number)	证书类型	日期	货号
I1428169	分析证书	22-07-19	M119522
A2213302	分析证书	22-02-12	M119522
B1410016	分析证书	22-01-21	M119522

1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu. (2023) The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis. DEVELOPMENTAL CELL, [PMID:37977150] [10.1016/j.devcel.2023.10.014]
2. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin. (2023) A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L.. Genes, 14 (6): (1287). [PMID:37372467] [10.3390/genes14061287]
3. Yu-Nan Chen, Xu-Yang Shen, Yue Yu, Chen-Yu Xue, Ying-Lin Zhou, Xin-Xiang Zhang. (2023) In-source fragmentation of nucleosides in electrospray ionization towards more sensitive and accurate nucleoside analysis. ANALYST, 148 (7): (1500-1506). [PMID:36883656] [10.1039/D3AN00047H]
4. Yu-Fang Ma, Fang Yuan, Yue Yu, Ying-Lin Zhou, Xin-Xiang Zhang. (2020) Synthesis of a pH-Responsive Functional Covalent Organic Framework via Facile and Rapid One-Step Postsynthetic Modification and Its Application in Highly Efficient N1-Methyladenosine Extraction. ANALYTICAL CHEMISTRY, 92 (1): (1424–1430). [PMID:31813221] [10.1021/acs.analchem.9b04600]

1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu. (2023) The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis. DEVELOPMENTAL CELL, [PMID:37977150] [10.1016/j.devcel.2023.10.014]
2. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin. (2023) A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L.. Genes, 14 (6): (1287). [PMID:37372467] [10.3390/genes14061287]
3. Yu-Nan Chen, Xu-Yang Shen, Yue Yu, Chen-Yu Xue, Ying-Lin Zhou, Xin-Xiang Zhang. (2023) In-source fragmentation of nucleosides in electrospray ionization towards more sensitive and accurate nucleoside analysis. ANALYST, 148 (7): (1500-1506). [PMID:36883656] [10.1039/D3AN00047H]
4. Yu-Fang Ma, Fang Yuan, Yue Yu, Ying-Lin Zhou, Xin-Xiang Zhang. (2020) Synthesis of a pH-Responsive Functional Covalent Organic Framework via Facile and Rapid One-Step Postsynthetic Modification and Its Application in Highly Efficient N1-Methyladenosine Extraction. ANALYTICAL CHEMISTRY, 92 (1): (1424–1430). [PMID:31813221] [10.1021/acs.analchem.9b04600]