L-赖氨酸-4,4,5,5-d₄盐酸盐

  • ≥98 atom% D,≥98%
有货

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
L472132-25mg
25mg 期货 Stock Image
L472132-100mg
100mg 期货 Stock Image

基本描述

别名 (S)-2,6-二氨基己酸-4,4,5,5-d4盐酸盐 | 氘代赖氨酸 | 氘化赖氨酸
英文别名 SILAC Amino Acid, Deuterated Lys, (S)-2,6-Diaminocaproic acid-4,4,5,5-d₄ hydrochloride, Deuterated lysine
规格或纯度 ≥98 atom% D,≥98%
英文名称 L-Lysine-4,4,5,5-d₄ hydrochloride
储存温度 充氩

名称和识别符

IUPAC Name (2S)-2,6-diamino-4,4,5,5-tetradeuteriohexanoic acid;hydrochloride
INCHI InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1/i1D2,2D2;
InChi Key BVHLGVCQOALMSV-UGJIAQRQSA-N
Canonical SMILES C(CCN)CC(C(=O)O)N.Cl
Isomeric SMILES [2H]C([2H])(C[C@@H](C(=O)O)N)C([2H])([2H])CN.Cl
PubChem CID 71310290
分子量 186.67

化学和物理性质

敏感性 易吸湿
分子量 186.670 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 5
精确质量Exact Mass 186.107 Da
单同位素质量Monoisotopic Mass 186.107 Da
拓扑极表面积Topological Polar Surface Area 89.300 Ų
重原子数Heavy Atom Count 11
形式电荷Formal Charge 0
复杂度Complexity 106.000
同位素原子数Isotope Atom Count 4
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 2

安全和危险性(GHS)

技术规格说明书

Isotopic purity(Atom % D) 98-100(%)
Purity(HPLC area) 98-100(%)
Appearance(L472132) White Powder
NMR Spectrum 1H Conforms to structure
Specific rotation [α]20/D(C=2, 5mol/L HCl) 17.7-23.7(°)

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

参考文献

1. Zhifei Chen,Fabian Leinisch,Ines Greco,Wei Zhang,Nan Shu,Christine Y Chuang,Marianne N Lund,Michael J Davies.  (2019-01-17)  Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula..  Free radical research,  53  ((1)): (68-81).  [PMID:30646774]
2. Zhifei Chen,Alina Kondrashina,Ines Greco,Luke F Gamon,Marianne N Lund,Linda Giblin,Michael J Davies.  (2019-04-25)  Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models..  Journal of agricultural and food chemistry,  67  ((19)): (5634-5646).  [PMID:31017422]
3. Daniele Musiani,Roberto Giambruno,Enrico Massignani,Marica Rosaria Ippolito,Marianna Maniaci,Sriganesh Jammula,Daria Manganaro,Alessandro Cuomo,Luciano Nicosia,Diego Pasini,Tiziana Bonaldi.  (2020-01-30)  PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin..  Cell reports,  30  ((4)): (1208-1222).  [PMID:31995759]
4. Ville Paakinaho,Joanna K Lempiäinen,Gianluca Sigismondo,Einari A Niskanen,Marjo Malinen,Tiina Jääskeläinen,Markku Varjosalo,Jeroen Krijgsveld,Jorma J Palvimo.  (2021-02-02)  SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites..  Nucleic acids research,  49  ((4)): (1951-1971).  [PMID:33524141]
5. Mohammad Sedigh Jasour,Liane Wagner,Ulrik K Sundekilde,Bodil K Larsen,Ines Greco,Vibeke Orlien,Karsten Olsen,Hanne T Rasmussen,Niels H Hjermitslev,Marianne Hammershøj,Anne J T Dalsgaard,Trine K Dalsgaard.  (2017-11-10)  A Comprehensive Approach to Assess Feathermeal as an Alternative Protein Source in Aquafeed..  Journal of agricultural and food chemistry,  65  ((48)): (10673-10684).  [PMID:29119793]

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