| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| G106899-25mg |
25mg |
现货  |
| |
| G106899-100mg |
100mg |
现货 |
|
| 别名 | 没食子儿茶素没食子酸酯 |
|---|---|
| 英文别名 | GCG | (-)-Gallocatechin 3-O-gallate | CCRIS 9286 | (-)-Gallocatechin gallate | Q27166763 | AKOS015901852 | NVP-XAA 225 | A844803 | (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | IRW3C4Y31Q | UNII-IR |
| 规格或纯度 | ≥98% |
| 英文名称 | (-)-Gallocatechin gallate |
| 应用 | 一种抗氧化剂 |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
一种抗氧化剂 An antioxidant |
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IUPAC Name | [(2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
| INCHI | InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m1/s1 |
| InChi Key | WMBWREPUVVBILR-NQIIRXRSSA-N |
| Canonical SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| Isomeric SMILES | C1[C@H]([C@@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| WGK Germany | 3 |
| RTECS | DH9000000 |
| 分子量 | 458.37 |
| Reaxy-Rn | 375093 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=375093&ln= |
| 密度 | 1.685 |
|---|---|
| 敏感性 | 对光和湿度敏感 |
| 熔点 | 218 °C |
| 分子量 | 458.400 g/mol |
| XLogP3 | 1.200 |
| 氢键供体数Hydrogen Bond Donor Count | 8 |
| 氢键受体数Hydrogen Bond Acceptor Count | 11 |
| 可旋转键计数Rotatable Bond Count | 4 |
| 精确质量Exact Mass | 458.085 Da |
| 单同位素质量Monoisotopic Mass | 458.085 Da |
| 拓扑极表面积Topological Polar Surface Area | 197.000 Ų |
| 重原子数Heavy Atom Count | 33 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 667.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | Warning |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 3 |
| RTECS | DH9000000 |
| Reaxy-Rn | 375093 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=375093&ln= |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
| Purity(HPLC) | 98-100（%） |
|---|---|
| Appearance（G106899) | White to Pink Powder |
| Proton NMR spectrum | Conforms to Structure |
| Solubility in H2O，Colorless to Faint Pink,Clear,5 mg/ml | pass |
| 1. Liu, et al.. (2020) Rapid Screening ?-Glucosidase Inhibitors from Natural Products by At-Line Nanofractionation with Parallel Mass Spectrometry and Bioactivity Assessment.. Journal of Chromatography A, 1635 (461740-461740). [PMID:33271429] |
| 2. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] [10.3390/plants12213707] |
| 3. Ming-Xi Zhou, Xing Tian, Zhong-Qin Wu, Ke Li, Zong-Jun Li. (2021) Fuzhuan brick tea supplemented with areca nuts: Effects on serum and gut microbiota in mice. JOURNAL OF FOOD BIOCHEMISTRY, 45 (5): (e13737). [PMID:33876445] [10.1111/jfbc.13737] |
| 4. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2021) Roasting process shaping the chemical profile of roasted green tea and the association with aroma features. FOOD CHEMISTRY, 353 (129428). [PMID:33714119] [10.1016/j.foodchem.2021.129428] |
| 5. Huanhuan Xu, Titi Liu, Jing Xu, Jin Li, Fei Chen, Zemin Xiang, Yewei Huang, Dongying Zhang, Lihong Hu, Banglei Zhang, Chengting Zi, Xuanjun Wang, Jun Sheng. (2019) Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (−)-epigallocatechin-3-gallate–β-cyclodextrin complex. RSC Advances, 9 (48): (28006-28018). [PMID:35558992] [10.1039/C9RA05889C] |
| 6. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2016) Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions. MOLECULES, 21 (10): (1345). [PMID:27735869] [10.3390/molecules21101345] |
| 7. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang. (2016) Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers. FOOD CHEMISTRY, 196 (347). [PMID:26593500] [10.1016/j.foodchem.2015.09.056] |
| 1. Y Sugita-Konishi,Y Hara-Kudo,F Amano,T Okubo,N Aoi,M Iwaki,S Kumagai. (1999-11-26) Epigallocatechin gallate and gallocatechin gallate in green tea catechins inhibit extracellular release of Vero toxin from enterohemorrhagic Escherichia coli O157:H7.. Biochimica et biophysica acta, 1472 ((1-2)): (42-50). [PMID:10572924] |
| 2. Ikuo Ikeda,Makoto Kobayashi,Tadateru Hamada,Koichi Tsuda,Hitomi Goto,Katsumi Imaizumi,Ayumu Nozawa,Akio Sugimoto,Takami Kakuda. (2003-12-04) Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate.. Journal of agricultural and food chemistry, 51 ((25)): (7303-7307). [PMID:14640575] |
| 3. Marlène Backleh-Sohrt,Perihan Ekici,Guenter Leupold,Harun Parlar. (2005-09-27) Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.. Journal of natural products, 68 ((9)): (1386-1389). [PMID:16180819] |
| 4. Deniz Tasdemir,Gabriela Lack,Reto Brun,Peter Rüedi,Leonardo Scapozza,Remo Perozzo. (2006-05-26) Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.. Journal of medicinal chemistry, 49 ((11)): (3345-3353). [PMID:16722653] |
| 5. Charles E Isaacs,Guang Y Wen,Weimin Xu,Jun Hua Jia,Lisa Rohan,Christopher Corbo,Vincenzo Di Maggio,Edmund C Jenkins,Sharon Hillier. (2008-01-16) Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.. Antimicrobial agents and chemotherapy, 52 ((3)): (962-970). [PMID:18195068] |
| 6. Eui Seok Shin,Jiyoung Park,Jae-Min Shin,Dooho Cho,Si Young Cho,Dong Wook Shin,Mira Ham,Jae Bum Kim,Tae Ryong Lee. (2008-03-04) Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme.. Bioorganic & medicinal chemistry, 16 ((7)): (3580-3586). [PMID:18313308] |
| 7. Sang Min Lee,Chae Wook Kim,Jung Kee Kim,Hyun Jung Shin,Joo Hyun Baik. (2008-03-28) GCG-rich tea catechins are effective in lowering cholesterol and triglyceride concentrations in hyperlipidemic rats.. Lipids, 43 ((5)): (419-429). [PMID:18365267] |
| 8. José Antonio Curiel,Héctor Rodríguez,Iván Acebrón,José Miguel Mancheño,Blanca De Las Rivas,Rosario Muñoz. (2009-07-16) Production and physicochemical properties of recombinant Lactobacillus plantarum tannase.. Journal of agricultural and food chemistry, 57 ((14)): (6224-6230). [PMID:19601665] |
| 9. Satoru Tamura,Kunichika Yoshihira,Katsuaki Fujiwara,Nobutoshi Murakami. (2010-03-06) New inhibitors for expression of IgE receptor on human mast cell.. Bioorganic & medicinal chemistry letters, 20 ((7)): (2299-2302). [PMID:20202836] |
| 10. Yunbao Liu,Muraleedharan G Nair. (2010-06-23) An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.. Journal of natural products, 73 ((7)): (1193-1195). [PMID:20565070] |
| 11. Fan Jiang,Wei Chen,Kejia Yi,Zhiqiang Wu,Yiling Si,Weidong Han,Yali Zhao. (2010-09-14) The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors.. Clinical immunology (Orlando, Fla.), 137 ((3)): (347-356). [PMID:20832370] |
| 12. Noelia López-Gutiérrez,Roberto Romero-González,Patricia Plaza-Bolaños,José Luis Martínez Vidal,Antonia Garrido Frenich. (2014-12-04) Identification and quantification of phytochemicals in nutraceutical products from green tea by UHPLC-Orbitrap-MS.. Food chemistry, 173 (607-618). [PMID:25466066] |
| 13. Zhonghua Liu,Yong Lin,Sheng Zhang,Die Wang,Qionglin Liang,Guoan Luo. (2015-06-04) Comparative proteomic analysis using 2DE-LC-MS/MS reveals the mechanism of Fuzhuan brick tea extract against hepatic fat accumulation in rats with nonalcoholic fatty liver disease.. Electrophoresis, 36 ((17)): (2002-2016). [PMID:26036873] |
| 14. R J Aitken,L Muscio,S Whiting,H S Connaughton,B A Fraser,B Nixon,N D Smith,G N De Iuliis. (2016-09-24) Analysis of the effects of polyphenols on human spermatozoa reveals unexpected impacts on mitochondrial membrane potential, oxidative stress and DNA integrity; implications for assisted reproductive technology.. Biochemical pharmacology, 121 (78-96). [PMID:27659810] |
| 15. Weidong Dai,Junfeng Tan,Meiling Lu,Yin Zhu,Pengliang Li,Qunhua Peng,Li Guo,Yue Zhang,Dongchao Xie,Zhengyan Hu,Zhi Lin. (2018-06-21) Metabolomics Investigation Reveals That 8-C N-Ethyl-2-pyrrolidinone-Substituted Flavan-3-ols Are Potential Marker Compounds of Stored White Teas.. Journal of agricultural and food chemistry, 66 ((27)): (7209-7218). [PMID:29921123] |
| 16. Seyit Yuzuak,James Ballington,De-Yu Xie. (2018-09-29) HPLC-qTOF-MS/MS-Based Profiling of Flavan-3-ols and Dimeric Proanthocyanidins in Berries of Two Muscadine Grape Hybrids FLH 13-11 and FLH 17-66.. Metabolites, 8 ((4)): [PMID:30261603] |
| 17. Liu, et al.. (2020) Rapid Screening ?-Glucosidase Inhibitors from Natural Products by At-Line Nanofractionation with Parallel Mass Spectrometry and Bioactivity Assessment.. Journal of Chromatography A, 1635 (461740-461740). [PMID:33271429] |
| 18. Lifeng Cai,Miriam Gochin. (2007-04-25) A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.. Antimicrobial agents and chemotherapy, 51 ((7)): (2388-2395). [PMID:17452484] |
| 19. Angelika S Rambold,Margit Miesbauer,Diana Olschewski,Ralf Seidel,Constanze Riemer,Lindsay Smale,Lisa Brumm,Michal Levy,Ehud Gazit,Dieter Oesterhelt,Michael Baier,Christian F W Becker,Martin Engelhard,Konstanze F Winklhofer,Jörg Tatzelt. (2008-08-12) Green tea extracts interfere with the stress-protective activity of PrP and the formation of PrP.. Journal of neurochemistry, 107 ((1)): (218-229). [PMID:18691383] |
| 20. Christine A Larsen,William H Bisson,Roderick H Dashwood. (2009-10-21) Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.. Journal of medicinal chemistry, 52 ((21)): (6543-6545). [PMID:19839593] |
| 21. Pavel Svoboda,Hana Vlčková,Lucie Nováková. (2015-05-31) Development and validation of UHPLC-MS/MS method for determination of eight naturally occurring catechin derivatives in various tea samples and the role of matrix effects.. Journal of pharmaceutical and biomedical analysis, 114 (62-70). [PMID:26025813] |
| 22. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] [10.3390/plants12213707] |
| 23. Ming-Xi Zhou, Xing Tian, Zhong-Qin Wu, Ke Li, Zong-Jun Li. (2021) Fuzhuan brick tea supplemented with areca nuts: Effects on serum and gut microbiota in mice. JOURNAL OF FOOD BIOCHEMISTRY, 45 (5): (e13737). [PMID:33876445] [10.1111/jfbc.13737] |
| 24. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2021) Roasting process shaping the chemical profile of roasted green tea and the association with aroma features. FOOD CHEMISTRY, 353 (129428). [PMID:33714119] [10.1016/j.foodchem.2021.129428] |
| 25. Huanhuan Xu, Titi Liu, Jing Xu, Jin Li, Fei Chen, Zemin Xiang, Yewei Huang, Dongying Zhang, Lihong Hu, Banglei Zhang, Chengting Zi, Xuanjun Wang, Jun Sheng. (2019) Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (−)-epigallocatechin-3-gallate–β-cyclodextrin complex. RSC Advances, 9 (48): (28006-28018). [PMID:35558992] [10.1039/C9RA05889C] |
| 26. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2016) Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions. MOLECULES, 21 (10): (1345). [PMID:27735869] [10.3390/molecules21101345] |
| 27. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang. (2016) Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers. FOOD CHEMISTRY, 196 (347). [PMID:26593500] [10.1016/j.foodchem.2015.09.056] |
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