| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| E135849-250mg |
250mg |
现货  |
| |
| E135849-1g |
1g |
现货 |
|
| 别名 | 3-酮去氧孕烯 |
|---|---|
| 英文别名 | C75537 | NCGC00168777-04 | 18,19-Dinor-17alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene- | s4673 | (17-alpha)-13-ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-on | 13-Ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4- |
| 规格或纯度 | Moligand™, ≥98%(HPLC) |
| 英文名称 | Etonogestrel |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 激动剂 |
| 作用机制 | 孕酮受体激动剂 |
| 产品介绍 |
Etonogestrel (3-Oxodesogestrel) 是孕激素去氧孕烯的生物活性代谢物，Etonogestrel 与靶器官中的孕酮受体 (progesterone receptor) 和雌激素受体 (estrogen receptors) 高亲和力地结合。Etonogestrel 诱导 FKBP51 mRNA 和蛋白表达。 Product Describtion: Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs)。 |
| ALogP | 3.3 |
|---|
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| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| PubChem SID | 488195871 |
|---|---|
| EC号 | 258-936-2 |
| 分子类型 | 小分子 |
| IUPAC Name | (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| INCHI | InChI=1S/C22H28O2/c1-4-21-13-14(3)20-17-9-7-16(23)12-15(17)6-8-18(20)19(21)10-11-22(21,24)5-2/h2,12,17-20,24H,3-4,6-11,13H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1 |
| InChi Key | GCKFUYQCUCGESZ-BPIQYHPVSA-N |
| Canonical SMILES | CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 |
| Isomeric SMILES | CC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34 |
| WGK Germany | 3 |
| RTECS | JF8290000 |
| PubChem CID | 6917715 |
| 分子量 | 324.46 |
| 比旋光度 | [α]/D +80 to +95°, c = 1 (CHCl3) |
|---|---|
| 分子量 | 324.500 g/mol |
| XLogP3 | 3.300 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 2 |
| 可旋转键计数Rotatable Bond Count | 2 |
| 精确质量Exact Mass | 324.209 Da |
| 单同位素质量Monoisotopic Mass | 324.209 Da |
| 拓扑极表面积Topological Polar Surface Area | 37.300 Ų |
| 重原子数Heavy Atom Count | 24 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 677.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 6 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| NMR Spectrum 1H | Conforms to Structure |
|---|---|
| Purity(HPLC area) | |
| Appearance(E135849) | White to beige Powder |
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