1,2-二硬脂酰基-sn-丙三基-3-磷脂酰乙醇胺(DSPE)

用C18:0脂肪酸酰化的磷酰乙醇胺磷脂
  • ≥97%
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
D130471-50mg
50mg 现货 Stock Image
D130471-250mg
250mg 现货 Stock Image
D130471-1g
1g 现货 Stock Image

基本描述

别名 1,2-双十八烷酰-锡-甘油-3-磷酸乙醇胺, 3-锡-磷脂酰乙醇胺,1,2-二硬脂酰, L-β,γ-二硬脂酰-α-脑磷脂 | 1,2-二硬脂酰-sn-甘油基-3-磷酸乙醇胺
英文别名 18:0 PE | 1,2-Distearoyl-sn-glycerophosphoethanolamine | AKOS027322756 | DISTEAROYL CEPHALIN | 1,2-Distearoyl-sn-Glycero-3-Phosphatidylethanolamine | BCP11133 | CHEBI:47766 | H10394 | 2-Aminoethyl (R)-2,3-Bis(octadecanoyloxy)propyl Hydrogen Phosphate | (2
规格或纯度 ≥97%
英文名称 1,2-distearoyl-sn-glycero-3-phosphoethanolamine
生化机理 磷酰基乙醇胺磷脂被C18:0脂肪酸酰化。scFv抗体的结合物。用于脂质双层研究和生物系统。
储存温度 -20°C储存
运输条件 超低温冰袋运输
备注 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。

AI解读

名称和识别符

EC号 213-963-9
IUPAC Name [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
INCHI InChI=1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1
InChi Key LVNGJLRDBYCPGB-LDLOPFEMSA-N
Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC
Isomeric SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC
WGK Germany 3
分子量 748.07
Beilstein号 1730641
Reaxy-Rn 1730642
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1730642&ln=

化学和物理性质

敏感性 对光线和热敏感
比旋光度 +6.0 to +8.0 deg(C=0.5, CHCl3:AcOH)
分子量 748.100 g/mol
XLogP3 12.400
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 9
可旋转键计数Rotatable Bond Count 43
精确质量Exact Mass 747.578 Da
单同位素质量Monoisotopic Mass 747.578 Da
拓扑极表面积Topological Polar Surface Area 134.000 Ų
重原子数Heavy Atom Count 51
形式电荷Formal Charge 0
复杂度Complexity 815.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
Reaxy-Rn 1730642
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1730642&ln=
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

技术规格说明书

Purity(HPLC)(CAD) 97-100(%)
Specific Rotation [a]20/D(c=0.5 in CHCL3:AcOH=1:1) 6-8(°)
Purity(NonaqueousTitration) 97-100(%)
Appearance(D130471) White to Off-White Powder or Solid or Chunks
Proton NMR spectrum Conforms to Structure
Solubility in CHCL3/MeOH 3/1 Colorless, Clear (visual), 20 mg/ml

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到17个结果

批号(Lot Number) 证书类型 日期 货号
H2408489 分析证书 25-05-07 D130471
H2408488 分析证书 25-05-07 D130471
C2401216 分析证书 25-03-10 D130471
D2525203 分析证书 24-10-23 D130471
D2525204 分析证书 24-10-23 D130471
D2525205 分析证书 24-10-23 D130471
H2408490 分析证书 24-07-18 D130471
G2222229 分析证书 24-02-20 D130471
C2401215 分析证书 24-02-05 D130471
G2222232 分析证书 23-05-10 D130471
G2222230 分析证书 23-05-10 D130471
G22222291 分析证书 23-05-10 D130471
L1927013 分析证书 23-04-14 D130471
H2130163 分析证书 22-06-23 D130471
H2130164 分析证书 22-06-23 D130471
H2130165 分析证书 22-06-23 D130471
C2127276 分析证书 22-01-18 D130471

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此产品的引用文献

1. Yan-ming Xia, Li-xin Hu, Yun-han Xia, Shi-xuan Li, Bo Shi, Chao Qin, Xiao-peng Han, Su-xin Li, Li-fang Yin.  (2024)  Rational surface modification of zirconium-based metal–organic framework nanomaterials for the adsorption and recovery of coloured drugs and proteins from aqueous solutions.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  681  (11): (132845).  [PMID:10660610] [10.1016/j.colsurfa.2023.132845]
2. Xinmin Guo, Jianru Lin, Liwen Pan, Kun He, Zhihui Huang, Jialin Chen, Cuiyan Lin, Baohui Zeng, Sijia Luo, Mengdie Wang.  (2023)  Ultrasound-triggered release of miR-199a-3p from liposome nanobubbles for enhanced hepatocellular carcinoma treatment.  Artificial Cells Nanomedicine and Biotechnology,  [PMID:37850395] [10.1080/21691401.2023.2268137]
3. Tianli Yang, Feng Zhao, Jun Zhao, Jian Geng, Cheng Shao, Jingyu Liu, Fei Sheng, Liuhua Zhou, Hua Xu, Ruipeng Jia.  (2023)  Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.  JOURNAL OF CONTROLLED RELEASE,  364  (15): (718).  [PMID:37944669] [10.1016/j.jconrel.2023.10.048]
4. Qian Ren, Xiaojing Zhang, Yangyi Sheng, Nuo Yu, Maoquan Li, Zhigang Chen.  (2023)  Phytic acid-Cu2+ framework/Cu2-xS nanocomposites with heat-shock protein down-modulation ability for enhanced multimodal combination therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  652  (15): (2116).  [PMID:37703681] [10.1016/j.jcis.2023.09.024]
5. Di Chuan, Rangrang Fan, Bo Chen, Yangmei Ren, Min Mu, Haifeng Chen, Bingwen Zou, Haohao Dong, Aiping Tong, Gang Guo.  (2023)  Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy.  ACS Applied Materials & Interfaces,  [PMID:37605506] [10.1021/acsami.3c07648]
6. Weilun Pan, Bodeng Wu, Chengtao Nie, Tingting Luo, Zhenli Song, Jie Lv, Yong Tan, Chunchen Liu, Mingzhen Zhong, Tong Liao, Zhenxun Wang, Guanghui Yi, Limin Zhang, Xiaoliu Liu, Bo Li, Jinxiang Chen, Lei Zheng.  (2023)  NIR-II Responsive Nanohybrids Incorporating Thermosensitive Hydrogel as Sprayable Dressing for Multidrug-Resistant-Bacteria Infected Wound Management.  ACS Nano,  17  (12): (11253–11267).  [PMID:37314783] [10.1021/acsnano.2c10742]
7. Yucai Zhang, Heon Gyu Kang, Hua-zhen Xu, Honghui Luo, Minoru Suzuki, Qing Lan, Xiao Chen, Naoki Komatsu, Li Zhao.  (2023)  Tumor Eradication by Boron Neutron Capture Therapy with 10B-enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(glycerol).  ADVANCED MATERIALS,  (2301479).  [PMID:37243974] [10.1002/adma.202301479]
8. Shuyi Zhu, Shuai Xu, Yujing Guo, Hongwen Zhang, Kun Ma, Junfeng Wang, Qian Zhao, Le Zhou, Weiping Cai.  (2023)  Defect Damping-Enhanced Plasmonic Photothermal Conversion.  ACS Nano,  17  (11): (10300–10312).  [PMID:37234025] [10.1021/acsnano.3c00657]
9. Chang Wang, Fang Wang, Wentao Zou, Yawei Miao, Yaowei Zhu, Mengyu Cao, Bing Yu, Hailin Cong, Youqing Shen.  (2023)  Donor-acceptor-donor small molecules for fluorescence/photoacoustic imaging and integrated photothermal therapy.  Acta Biomaterialia,  164  (588).  [PMID:37086828] [10.1016/j.actbio.2023.04.024]
10. Jingge Zhang, Enna Ha, Danyang Li, Shuqing He, Luyang Wang, Shaolong Kuang, Junqing Hu.  (2023)  Dual enzyme-like Co–FeSe2 nanoflowers with GSH degradation capability for NIR II-enhanced catalytic tumor therapy.  Journal of Materials Chemistry B,  11  (19): (4274-4286).  [PMID:37140154] [10.1039/D3TB00220A]
11. Run Han, Zhuyifan Ye, Yunsen Zhang, Yaxin Cheng, Ying Zheng, Defang Ouyang.  (2023)  Predicting liposome formulations by the integrated machine learning and molecular modeling approaches.  Asian Journal of Pharmaceutical Sciences,  18  (100811).  [PMID:37274923] [10.1016/j.ajps.2023.100811]
12. Yanyun Lin, Xingjuan Wu, Kaicheng Wang, Sen Shang, Yubin Gong, Hongwei Zhao, Dai Wu, Peng Zhang, Xiaoyun Lu.  (2023)  Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (8): (7111).  [PMID:37108273] [10.3390/ijms24087111]
13. Jiaping Zhou, Qiaomei Zhou, Gaofeng Shu, Xiaojie Wang, Yuanfei Lu, Haiyan Chen, Tingting Hu, Jinsong Cai, Yongzhong Du, Risheng Yu.  (2023)  Dual-Effect of Magnetic Resonance Imaging Reporter Gene in Diagnosis and Treatment of Hepatocellular Carcinoma.  International Journal of Nanomedicine,  [PMID:33061378] [10.2147/IJN.S257628]
14. Shulong Wang, Yanni Luo, Changchun Wen, Shulin Zhao, Liangliang Zhang.  (2023)  An autocatalytically-activatable hydrogen peroxide photoacoustic sensor for in situ visualization precise diagnosis and drug intervention tracing in diabetes syndrome.  BIOSENSORS & BIOELECTRONICS,  222  (114964).  [PMID:36493721] [10.1016/j.bios.2022.114964]
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16. Rui Zhang, Changlin Liu, Ruoxi Zhao, Yaqian Du, Dan Yang, He Ding, Guixin Yang, Shili Gai, Fei He, Piaoping Yang.  (2022)  Engineering oxygen vacancy of MoOx nanoenzyme by Mn doping for dual-route cascaded catalysis mediated high tumor eradication.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  623  (155).  [PMID:35576647] [10.1016/j.jcis.2022.05.037]
17. Lixia Gao, Jie Yang, Jutao Feng, Ziying Liu, Ying Dong, Jiangyan Luo, Liangzhentian Yu, Jiamei Wang, Hongying Fan, Weifeng Ma, Tiancai Liu.  (2022)  PreS/2-21-Guided siRNA Nanoparticles Target to Inhibit Hepatitis B Virus Infection and Replication..  Frontiers in Immunology,  13  (856463-856463).  [PMID:35572586] [10.3389/fimmu.2022.856463]
18. Wei Zhang, Yang Zang, Yanli Lu, Jinghui Han, Qingyun Xiong, Jinping Xiong.  (2022)  Synthesis of Rare-Earth Nanomaterials Ag-Doped NaYF4:Yb3+/Er3+@NaYF4:Nd3+@NaGdF4 for In Vivo Imaging.  Nanomaterials,  12  (5): (728).  [PMID:35269216] [10.3390/nano12050728]
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20. Qian Li, Yaxin Zhou, Weidong He, Xiaomeng Ren, Mengzhu Zhang, Yue Jiang, Zhaocai Zhou, Yuxia Luan.  (2021)  Platelet-armored nanoplatform to harmonize janus-faced IFN-γ against tumor recurrence and metastasis.  JOURNAL OF CONTROLLED RELEASE,  338  (33).  [PMID:34391837] [10.1016/j.jconrel.2021.08.020]
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24. Yanzi Xu, Haoke Zhang, Ning Zhang, Xiaochi Wang, Dongfeng Dang, Xunan Jing, Duo Xi, Ying Hao, Ben Zhong Tang, Lingjie Meng.  (2020)  Deep-Red Fluorescent Organic Nanoparticles with High Brightness and Photostability for Super-Resolution in Vitro and in Vivo Imaging Using STED Nanoscopy.  ACS Applied Materials & Interfaces,  12  (6): (6814–6826).  [PMID:31880157] [10.1021/acsami.9b18336]
25. Ding Yi, Zhu Yingmei, Wei Shaohua, Zhou Jiahong, Shen Jian.  (2019)  Cancer cell membrane as gate keeper of mesoporous silica nanoparticles and photothermal-triggered membrane fusion to release the encapsulated anticancer drug.  JOURNAL OF MATERIALS SCIENCE,  54  (19): (12794-12805).  [10.1007/s10853-019-03788-y]
26. Jinfeng Ma, Hongzhang Deng, Fuli Zhao, Liandong Deng, Weiwei Wang, Anjie Dong, Jianhua Zhang.  (2018)  Liposomes-Camouflaged Redox-Responsive Nanogels to Resolve the Dilemma between Extracellular Stability and Intracellular Drug Release.  MACROMOLECULAR BIOSCIENCE,  18  (7): (1800049).  [PMID:29732706] [10.1002/mabi.201800049]
27. Ang Li, Xiang Li, Xujiang Yu, Wei Li, Ruyi Zhao, Xiao An, Daxiang Cui, Xiaoyuan Chen, Wanwan Li.  (2017)  Synergistic thermoradiotherapy based on PEGylated Cu3BiS3 ternary semiconductor nanorods with strong absorption in the second near-infrared window.  BIOMATERIALS,  112  (164).  [PMID:27768971] [10.1016/j.biomaterials.2016.10.024]

参考文献

1. Yan-ming Xia, Li-xin Hu, Yun-han Xia, Shi-xuan Li, Bo Shi, Chao Qin, Xiao-peng Han, Su-xin Li, Li-fang Yin.  (2024)  Rational surface modification of zirconium-based metal–organic framework nanomaterials for the adsorption and recovery of coloured drugs and proteins from aqueous solutions.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  681  (11): (132845).  [PMID:10660610] [10.1016/j.colsurfa.2023.132845]
2. Xinmin Guo, Jianru Lin, Liwen Pan, Kun He, Zhihui Huang, Jialin Chen, Cuiyan Lin, Baohui Zeng, Sijia Luo, Mengdie Wang.  (2023)  Ultrasound-triggered release of miR-199a-3p from liposome nanobubbles for enhanced hepatocellular carcinoma treatment.  Artificial Cells Nanomedicine and Biotechnology,  [PMID:37850395] [10.1080/21691401.2023.2268137]
3. Tianli Yang, Feng Zhao, Jun Zhao, Jian Geng, Cheng Shao, Jingyu Liu, Fei Sheng, Liuhua Zhou, Hua Xu, Ruipeng Jia.  (2023)  Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.  JOURNAL OF CONTROLLED RELEASE,  364  (15): (718).  [PMID:37944669] [10.1016/j.jconrel.2023.10.048]
4. Qian Ren, Xiaojing Zhang, Yangyi Sheng, Nuo Yu, Maoquan Li, Zhigang Chen.  (2023)  Phytic acid-Cu2+ framework/Cu2-xS nanocomposites with heat-shock protein down-modulation ability for enhanced multimodal combination therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  652  (15): (2116).  [PMID:37703681] [10.1016/j.jcis.2023.09.024]
5. Di Chuan, Rangrang Fan, Bo Chen, Yangmei Ren, Min Mu, Haifeng Chen, Bingwen Zou, Haohao Dong, Aiping Tong, Gang Guo.  (2023)  Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy.  ACS Applied Materials & Interfaces,  [PMID:37605506] [10.1021/acsami.3c07648]
6. Weilun Pan, Bodeng Wu, Chengtao Nie, Tingting Luo, Zhenli Song, Jie Lv, Yong Tan, Chunchen Liu, Mingzhen Zhong, Tong Liao, Zhenxun Wang, Guanghui Yi, Limin Zhang, Xiaoliu Liu, Bo Li, Jinxiang Chen, Lei Zheng.  (2023)  NIR-II Responsive Nanohybrids Incorporating Thermosensitive Hydrogel as Sprayable Dressing for Multidrug-Resistant-Bacteria Infected Wound Management.  ACS Nano,  17  (12): (11253–11267).  [PMID:37314783] [10.1021/acsnano.2c10742]
7. Yucai Zhang, Heon Gyu Kang, Hua-zhen Xu, Honghui Luo, Minoru Suzuki, Qing Lan, Xiao Chen, Naoki Komatsu, Li Zhao.  (2023)  Tumor Eradication by Boron Neutron Capture Therapy with 10B-enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(glycerol).  ADVANCED MATERIALS,  (2301479).  [PMID:37243974] [10.1002/adma.202301479]
8. Shuyi Zhu, Shuai Xu, Yujing Guo, Hongwen Zhang, Kun Ma, Junfeng Wang, Qian Zhao, Le Zhou, Weiping Cai.  (2023)  Defect Damping-Enhanced Plasmonic Photothermal Conversion.  ACS Nano,  17  (11): (10300–10312).  [PMID:37234025] [10.1021/acsnano.3c00657]
9. Chang Wang, Fang Wang, Wentao Zou, Yawei Miao, Yaowei Zhu, Mengyu Cao, Bing Yu, Hailin Cong, Youqing Shen.  (2023)  Donor-acceptor-donor small molecules for fluorescence/photoacoustic imaging and integrated photothermal therapy.  Acta Biomaterialia,  164  (588).  [PMID:37086828] [10.1016/j.actbio.2023.04.024]
10. Jingge Zhang, Enna Ha, Danyang Li, Shuqing He, Luyang Wang, Shaolong Kuang, Junqing Hu.  (2023)  Dual enzyme-like Co–FeSe2 nanoflowers with GSH degradation capability for NIR II-enhanced catalytic tumor therapy.  Journal of Materials Chemistry B,  11  (19): (4274-4286).  [PMID:37140154] [10.1039/D3TB00220A]
11. Run Han, Zhuyifan Ye, Yunsen Zhang, Yaxin Cheng, Ying Zheng, Defang Ouyang.  (2023)  Predicting liposome formulations by the integrated machine learning and molecular modeling approaches.  Asian Journal of Pharmaceutical Sciences,  18  (100811).  [PMID:37274923] [10.1016/j.ajps.2023.100811]
12. Yanyun Lin, Xingjuan Wu, Kaicheng Wang, Sen Shang, Yubin Gong, Hongwei Zhao, Dai Wu, Peng Zhang, Xiaoyun Lu.  (2023)  Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (8): (7111).  [PMID:37108273] [10.3390/ijms24087111]
13. Jiaping Zhou, Qiaomei Zhou, Gaofeng Shu, Xiaojie Wang, Yuanfei Lu, Haiyan Chen, Tingting Hu, Jinsong Cai, Yongzhong Du, Risheng Yu.  (2023)  Dual-Effect of Magnetic Resonance Imaging Reporter Gene in Diagnosis and Treatment of Hepatocellular Carcinoma.  International Journal of Nanomedicine,  [PMID:33061378] [10.2147/IJN.S257628]
14. Shulong Wang, Yanni Luo, Changchun Wen, Shulin Zhao, Liangliang Zhang.  (2023)  An autocatalytically-activatable hydrogen peroxide photoacoustic sensor for in situ visualization precise diagnosis and drug intervention tracing in diabetes syndrome.  BIOSENSORS & BIOELECTRONICS,  222  (114964).  [PMID:36493721] [10.1016/j.bios.2022.114964]
15. Jiang Mingyue, Chen Le, Chen Bo, Yu Qinghua, Zhang Xianming, Jing Weihong, Ma Limei, Deng Tao, Yang Zhangyou, Yu Chao.  (2022)  Intracellular K+-Responsive Block Copolymer Micelles for Targeted Drug Delivery of Curcumin.  Frontiers in Bioengineering and Biotechnology,  10  [PMID:35845402] [10.3389/fbioe.2022.919189]
16. Rui Zhang, Changlin Liu, Ruoxi Zhao, Yaqian Du, Dan Yang, He Ding, Guixin Yang, Shili Gai, Fei He, Piaoping Yang.  (2022)  Engineering oxygen vacancy of MoOx nanoenzyme by Mn doping for dual-route cascaded catalysis mediated high tumor eradication.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  623  (155).  [PMID:35576647] [10.1016/j.jcis.2022.05.037]
17. Lixia Gao, Jie Yang, Jutao Feng, Ziying Liu, Ying Dong, Jiangyan Luo, Liangzhentian Yu, Jiamei Wang, Hongying Fan, Weifeng Ma, Tiancai Liu.  (2022)  PreS/2-21-Guided siRNA Nanoparticles Target to Inhibit Hepatitis B Virus Infection and Replication..  Frontiers in Immunology,  13  (856463-856463).  [PMID:35572586] [10.3389/fimmu.2022.856463]
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