(+)-生物素-PEG 4 -丙酸

1篇引用文献

≥97%

CAS编号: 721431-18-1
分子式: C₂₁H₃₇N₃SO₈
分子量: 491.6
MDL号: MFCD08457831
PubChem编号: 17040189

有货

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
B419748-50mg	50mg	现货
B419748-250mg	250mg	现货

查看相关系列

PROTAC (2093) PROTAC连接器 (1909)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	生物素-PEG4-丙酸 \| 15-(生物素酰胺)-4,7,10,13-四氧杂十五烷酸
英文别名	Biotin-PEG4-Acid \| 721431-18-1 \| Biotin-peg4-propionic acid \| 3-Amino(peg4)propionic acid biotinamide \| (+)-Biotin-PEG4-CH2CH2COOH \| 17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosanoic acid \| 15-[D-(+)-Biotinyla
规格或纯度	≥97%
英文名称	(+)-Biotin-PEG₄-propionic acid
储存温度	避光,-20°C储存,充氩
运输条件	超低温冰袋运输
产品介绍	dPEG4 biotin acid consists of biotin and a propionic acid-functionalized tetraethylene glycol derivative. Numerous functional or reactive groups can modify the terminal acid moiety, including the acylating agents N-hydroxysuccinimide (NHS) and 2,3,5,6-tetrafluorophenol (TFP). Also, dPEG4 biotin acid reacts directly with primary amines using a suitable carbodiimide such as 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). The amphiphilic dPEG linker gives biotin excellent solubility in water and aqueous buffer, where biotin usually is poorly soluble. dPEG4 biotin acid offers significantly superior solubility and performance characteristics compared to the traditional, highly hydrophobic biotinylation reagent known as LC-biotin. Moreover, although dPEG4 biotin acid and LC-biotin have comparable linker lengths, dPEG4 biotin acid will not trigger the aggregation and precipitation of conjugated biomolecules, even at high levels of biotin incorporation on the biomolecule. In contrast, LC-biotin triggers the aggregation and precipitation of biomolecules with the incorporation of a few LC-biotin groups onto the biomolecule.

AI解读

名称和识别符

IUPAC Name	3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
INCHI	InChI=1S/C21H37N3O8S/c25-18(4-2-1-3-17-20-16(15-33-17)23-21(28)24-20)22-6-8-30-10-12-32-14-13-31-11-9-29-7-5-19(26)27/h16-17,20H,1-15H2,(H,22,25)(H,26,27)(H2,23,24,28)/t16-,17-,20-/m0/s1
InChi Key	GYOXFFWLRKVJJX-ZWOKBUDYSA-N
Canonical SMILES	C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)O)NC(=O)N2
Isomeric SMILES	C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)O)NC(=O)N2
分子量	491.6
Reaxy-Rn	9678492
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9678492&ln=

化学和物理性质

敏感性	对光敏感、吸湿、对热敏感
熔点	127 °C
分子量	491.600 g/mol
XLogP3	-1.000
氢键供体数Hydrogen Bond Donor Count	4
氢键受体数Hydrogen Bond Acceptor Count	9
可旋转键计数Rotatable Bond Count	20
精确质量Exact Mass	491.23 Da
单同位素质量Monoisotopic Mass	491.23 Da
拓扑极表面积Topological Polar Surface Area	170.000 Å²
重原子数Heavy Atom Count	33
形式电荷Formal Charge	0
复杂度Complexity	598.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	3
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

Reaxy-Rn	9678492
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9678492&ln=

SDS英文版

技术规格说明书

Purity(HPLC)	97-100（%）
Proton NMR spectrum	Conforms to structure

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到2个结果

批号(Lot Number)	证书类型	日期	货号
F2202096	分析证书	22-06-08	B419748
F2202114	分析证书	22-06-08	B419748

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Xiaohua Xie, Xiaofeng Wu, Dongsheng Zhao, Ying Liu, Qiyue Du, Yitian Li, Yaping Xu, Yuhang Li, Yan Qiu, Yungang Yang. (2023) Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway. PHARMACOLOGICAL RESEARCH, 187 (106577). [PMID:36435270] [10.1016/j.phrs.2022.106577]

参考文献

1. Xiaohua Xie, Xiaofeng Wu, Dongsheng Zhao, Ying Liu, Qiyue Du, Yitian Li, Yaping Xu, Yuhang Li, Yan Qiu, Yungang Yang. (2023) Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway. PHARMACOLOGICAL RESEARCH, 187 (106577). [PMID:36435270] [10.1016/j.phrs.2022.106577]