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黄芩素

类黄酮。脂氧合酶抑制剂。
46篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
B107324-100mg
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B107324-1g
 1g 现货 Stock Image
B107324-5g
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B107324-25g
 25g 现货 Stock Image
B107324-100g
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Anti-infection (2825) Apoptosis (1467) Ferroptosis (208) Influenza Virus (253) Metabolic Enzyme/Protease (4888) 六元杂环化合物 (1702) 苯丙素类 (152) 黄嘌呤氧化酶 (24)
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基本描述

别名 三羟黄酮 | 5,6,7-三羟基黄酮
英文别名 SpecPlus_000758 | Spectrum5_001418 | W-202870 | baicalein | BAICALEIN [WHO-DD] | MFCD00017459 | SDCCGMLS-0066744.P001 | NCGC00025282-01 | NCGC00025282-02 | NCGC00025282-03 | BAICALEIN [INCI] | Baicalein, 98% | HMS3412F14 | HMS3655P18 | MLS002473007 | NCGC
规格或纯度 Moligand™, ≥98%
英文名称 Baicalein
生化机理 尼泊尔和中日天然药中的黄酮类成分。黄芩素是黄芩的主要黄酮，可抑制花生四烯酸代谢的12-脂氧合酶（12-LOX）途径，该途径可抑制癌细胞增殖并诱导细胞凋亡。
储存温度 2-8°C储存
运输条件 冰袋运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

黄芩素是黄酮类化合物，是黄嘌呤氧化酶抑制剂。研究了黄芩素在人外周白细胞中的抗炎作用。 
应用  
黄芩素曾用于研究脂氧合酶的体外定量抑制。

Baicalein is a cell-permeable flavone, originally isolated from the roots of Scutellaria baicalensis, that inhibits cellular Ca2+ uptake, calcium mobilization, and adjuvant-induced arthritis. Baicalein has been shown to inhibit platelet 5-LO (5-lipoxygenase) (IC50=9.5 mM) and 12-LO (12-lipoxygenases) (IC50=0.12 mM) and reverse transcriptase. Baicalein reduces leukotriene biosynthesis and inhibits the release of lysosomal enzymes. Baicalein is a potent anti-inflammatory and anti-tumor agent, and it blocks PREP (prolyl oligopeptidase). Baicalein induces the S-phase arrest and apoptosis in proliferation of human lung squamous carcinoma CH27 cells. The declining expression of cdk1, cdk2, cyclin D2 and cyclin A by Baicalein resulted in the G1 and G2 cell cycle arrest in C6 rat glioma cells. Baicalein has anti-thrombotic, antiproliferative and anti-mitogenic effects. Baicalein inhibits protein tyrosine kinase in leukemia (CEM) cells and PMA-stimulated PKC (protein kinase C). Baicalein is an inhibitor of 15-LO and CYP2C9.
An inhibitor of Ca2+ uptake, 5-LO, and 12-LO

AI解读

关联靶点（人）

CYP1A2 Tchem 细胞色素 P450 1A2(Cytochrome P450 1A2) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CYP1B1 Tchem 细胞色素 P450 1B1(Cytochrome P450 1B1) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ALOX12 Tchem 花生四烯酸12-脂氧合酶，12S型(Arachidonate 12-lipoxygenase, 12S-type) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
ALOX15 Tchem 花生四烯酸15-脂氧合酶(Arachidonate 15-lipoxygenase) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
MGAM Tclin Maltase-glucoamylase (654 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABAT Tclin Gamma-amino-N-butyrate transaminase (140 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TNF Tclin TNF-alpha (1897 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MME Tclin Neprilysin (838 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ANPEP Tchem Aminopeptidase N (863 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
JUN Tchem Proto-oncogene c-JUN (434 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1B1 Tchem Cytochrome P450 1B1 (1148 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNA5 Tclin Voltage-gated potassium channel subunit Kv1.5 (1353 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NEU2 Tbio Sialidase 2 (382 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALB Tchem Serum albumin (2651 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIM1 Tchem Serine/threonine-protein kinase PIM1 (9629 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DAPK1 Tchem Death-associated protein kinase 1 (1664 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FBP1 Tchem Fructose-1,6-bisphosphatase (1199 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B3 Tchem Estradiol 17-beta-dehydrogenase 3 (821 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HBB Tbio Hemoglobin beta chain (329 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SI Tchem Sucrase-isomaltase (84 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AKT1 Tchem Serine/threonine-protein kinase AKT (9192 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SELL Tchem Leukocyte adhesion molecule-1 (145 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
YES1 Tclin Tyrosine-protein kinase YES (2781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
C8166 (1658 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Huh-7 (12904 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Htr7 Serotonin 7 (5-HT7) receptor (19 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Glo1 Glyoxalase I (4 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypsin (394 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cruzipain (33337 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DPP4 Dipeptidyl peptidase IV (11 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Sele Selectin E (1 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Selp P-selectin (7 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PREP Prolyl endopeptidase (14 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Abcb1b P-glycoprotein 1 (174 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mycobacterium tuberculosis (203094 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pichia kudriavzevii (7448 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aspergillus fumigatus (16427 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nakaseomyces glabratus (9108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida parapsilosis (8521 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida tropicalis (8381 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton rubrum (3646 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Human immunodeficiency virus 1 (70413 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
West Nile virus (623 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
3T3-L1 (3664 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RBL-2H3 (1162 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Vero (26788 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Calf thymus DNA (4845 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Urease (750 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Avian myoblastosis virus polyprotein II (68 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Dengue virus type 2 NS3 protein (2214 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A (1629 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ddn Putative uncharacterized protein (49 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Danio rerio (3092 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
dengue virus type 2 (2400 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Spodoptera litura (1708 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton mentagrophytes (4846 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ntrk2 BDNF/NT-3 growth factors receptor (124 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504763363
分子类型 小分子
IUPAC Name 5,6,7-trihydroxy-2-phenylchromen-4-one
INCHI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChi Key FXNFHKRTJBSTCS-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O
Isomeric SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O
WGK Germany 3
RTECS DJ3100898
PubChem CID 5281605
分子量 270.24
Beilstein号 272683
Reaxy-Rn 272683

化学和物理性质

溶解性 Soluble in alcohol, methanol, ether, acetone, ethyl acetate, hot glacial acetic acid, dilute sodium hydroxide, and DMSO (50 mM). Insoluble in water
密度 1.548
敏感性 对光和热敏感
熔点 256-271°C
分子量 270.240 g/mol
XLogP3 1.700
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 270.053 Da
单同位素质量Monoisotopic Mass 270.053 Da
拓扑极表面积Topological Polar Surface Area 87.000 Ų
重原子数Heavy Atom Count 20
形式电荷Formal Charge 0
复杂度Complexity 412.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
RTECS DJ3100898
Reaxy-Rn 272683
Merck Index 942
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

 SDS英文版

技术规格说明书

Purity(HPLC) 98-100（%）
Carbon by Elemental Analysis 65-68.3（%）
Appearance（B107324) Yellow to Gold to Orange or Brown Powder or Chunks
Infrared spectrum Conforms to Structure
Proton NMR spectrum Conforms to Structure

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到23个结果

批号(Lot Number) 证书类型 日期 货号
D2523096 分析证书 25-03-29 B107324
D2523100 分析证书 25-03-29 B107324
D2523097 分析证书 25-03-29 B107324
D2523098 分析证书 25-03-29 B107324
D2523099 分析证书 25-03-29 B107324
C2511370 分析证书 24-08-01 B107324
B2506060 分析证书 24-06-13 B107324
F2425099 分析证书 24-06-13 B107324
F2425102 分析证书 24-06-13 B107324
F2425103 分析证书 24-06-13 B107324
F2425104 分析证书 24-06-13 B107324
J2323111 分析证书 23-10-11 B107324
J2323112 分析证书 23-10-11 B107324
J2323113 分析证书 23-10-11 B107324
J2323114 分析证书 23-10-11 B107324
C2204120 分析证书 22-02-11 B107324
C2204137 分析证书 22-02-11 B107324
C2204142 分析证书 22-02-11 B107324
C2204148 分析证书 22-02-11 B107324
G2212111 分析证书 22-02-11 B107324
K2211280 分析证书 22-02-11 B107324
G2328022 分析证书 22-02-11 B107324
H2308245 分析证书 22-02-11 B107324

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1. Lei Liu, Yingyu Sima, Jinxia Feng, Shuting Shi, Aiting Chen, Chuanqin Zhou, Quanguo He, Yimin Tan.  (2024)  Bismuth oxide and nitrogen-doped reduced graphene oxide co-modified glassy carbon electrode to perform sensitive electrochemical sensing and determination of chrysin in pharmaceutical capsules.  MICROCHEMICAL JOURNAL,  196  (109544).  [PMID:1341900] [10.1016/j.microc.2023.109544]
2. Yongbing Xu, Yawen Li, Guilin Chen, Minxia Fan, Guangwan Hu, Mingquan Guo.  (2023)  Screening and identification of potential hypoglycemic and hypolipidemic compounds from aqueous extract of Scutellaria baicalensis Georgi root combing affinity ultrafiltration with multiple drug targets and in silico analysis.  PHYTOCHEMICAL ANALYSIS,  (15): [PMID:37779216] [10.1002/pca.3285]
3. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu.  (2023)  Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.  ACS Applied Materials & Interfaces,  15  (35): (41287–41298).  [PMID:37632730] [10.1021/acsami.3c06996]
4. Shuting Shi, Yanping Wei, Jinxia Feng, Chuanqin Zhou, Jinsong Zuo, Liangyuan Yao, Jianhua Ding, Kanghua Li, Quanguo He.  (2023)  Facile and ultrasensitive electrochemical detection of baicalein on bismuth oxide-carboxylated multi-walled carbon nanotube/glassy carbon electrode.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  123  (105557).  [10.1016/j.jfca.2023.105557]
5. Yufeng Chen, Guobin Xia, Chunfeng Wang, Huawei Wu, Xiaogang Xu, Genxiang Mao, Jiong Wu, Zhenlei Zhao.  (2023)  Impact of dietary plant flavonoids on 7,8-dihydroxyflavone transepithelial transport in human intestinal Caco-2 cells.  Food Science & Nutrition,  [PMID:37970375] [10.1002/fsn3.3581]
6. Xin Liu, Wei Niu, Jiamin Liu, Zhao Cui, Jiazheng Li, Zhenhai Zhang, Jianming Ju.  (2023)  Preparation of β-cyclodextrin and hydroxypropyl-β-cyclodextrin inclusion complexes of baicalein and evaluation of their effects on dextran sulfate sodium-induced acute ulcerative colitis in mice.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  87  (104714).  [10.1016/j.jddst.2023.104714]
7. Liao Zhenkun, Liu Xiaojuan, Zheng Juan, Zhao Chenning, Wang Dengliang, Xu Yang, Sun Chongde.  (2023)  A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus.  PLANT PHYSIOLOGY,  [PMID:37086474] [10.1093/plphys/kiad249]
8. Yameng Liu.  (2023)  Detection of LPS-induced macrophage activation with single-cell resolution through DC insulator-based electrokinetic devices.  ELECTROPHORESIS,  44  (11-12): (978-987).  [PMID:36996424] [10.1002/elps.202200274]
9. Xin-Mei Xie, Jiao-Jiao Hao, Jun-Zhuo Shi, Yun-Feng Zhou, Peng-Fei Liu, Feng Wang, Xiao-Ming Zheng, Xiu-Ying Yu, Chen-Chen Wang, Yi Yan, Guan-Hua Du, Jun-Ke Song, Yang-Yang He, Xiao-Bin Pang.  (2023)  Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.  INTERNATIONAL IMMUNOPHARMACOLOGY,  118  (109994).  [PMID:37098656] [10.1016/j.intimp.2023.109994]
10. Shuoshuo Yang, Guoqi Ni, Mengyang Xia, Hailing Li, Zhonghong Gao.  (2023)  Mussel inspired multifunctional bovine serum albumin (BSA) coatings loaded with Baicalein (BAI) to enhance osteogenesis and resist oxidative stress for potential application on implant.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  229  (752).  [PMID:36586655] [10.1016/j.ijbiomac.2022.12.285]
11. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2023)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,  6  (100424).  [PMID:36618100] [10.1016/j.crfs.2022.100424]
12. Zeng Wanying, Liu Xiaojing, Wu Yangyang, Cai Yuting, Li Zhennan, Ye Fei, Sun Yuanhong, Li Feng, Xing Huijie, Wang Shuai.  (2022)  Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis.  Frontiers in Pharmacology,  13  [PMID:36408246] [10.3389/fphar.2022.1053610]
13. Jingyi Hu, Yiheng Tong, Zhaofeng Shen, Yanan Li, Cheng Cheng, Ryan Au, Feng Xu, Yajun Liu, Lei Zhu, Hong Shen.  (2022)  Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.  BIOMEDICINE & PHARMACOTHERAPY,  154  (113571).  [PMID:36007273] [10.1016/j.biopha.2022.113571]
14. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu.  (2022)  Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system.  Analytical Methods,  14  (37): (3632-3637).  [PMID:36052693] [10.1039/D2AY01019D]
15. Zou Linghui, Zhang Zhongbin, Chen Jinqing, Yang Xu, Li Yuyang, Tang Jing, Du Xiaolu, Tang Ling, Liang Dan, Zhu Xiaoyong, Feng Jianfang, Ding Wenya.  (2022)  β-Cyclodextrin-Grafted Chitosan Enhances Intestinal Drug Absorption and Its Preliminary Mechanism Exploration.  AAPS PHARMSCITECH,  23  (6): (1-11).  [PMID:35948815] [10.1208/s12249-022-02380-z]
16. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372] [10.1039/D1FO03816H]
17. Feng-wei Zhang, Li-yang Peng, Chuan-Jian Shi, Jian-chi Li, Feng-xiang Pang, Wei-ming Fu, Xiao-hua Pan, Jin-fang Zhang.  (2022)  Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis.  Journal of Orthopaedic Translation,  33  (132).  [PMID:35330943] [10.1016/j.jot.2021.12.001]
18. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+.  FOOD CHEMISTRY,  385  (132656).  [PMID:35279499] [10.1016/j.foodchem.2022.132656]
19. Zhao Yan, Hu Jin-Jie, Bai Xiao-Lin, Liu Hao-Peng, Qi Xu-Wei, Liao Xun.  (2022)  Fast screening of tyrosinase inhibitors from traditional Chinese medicinal plants by ligand fishing in combination with in situ fluorescent assay.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  414  (6): (2265-2273).  [PMID:34982177] [10.1007/s00216-021-03864-w]
20. Qingxin Song, Shanxin Peng, Xiaosong Zhu.  (2021)  Baicalein protects against MPP+/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson’s disease.  NEUROTOXICOLOGY,  87  (188).  [PMID:34666128] [10.1016/j.neuro.2021.10.003]
21. Jing Liang, Ke Min, Piao Long, Xuqian Weng, Qun Huang, Bo Chen, Ming Ma.  (2021)  Selective adsorption of flavonoids on cerium-doped ferroferric oxide magnetic particles.  JOURNAL OF CHROMATOGRAPHY A,  1648  (462189).  [PMID:33975082] [10.1016/j.chroma.2021.462189]
22. Changjun Hu, Zhenkun Mao, Zhentao Li, Qiaoyan Li, Zilin Chen.  (2021)  Benzoic acid-modified monolithic column for separation of hydrophilic compounds by capillary electrochromatography with high content of water in mobile phase.  JOURNAL OF CHROMATOGRAPHY A,  1647  (462166).  [PMID:33957344] [10.1016/j.chroma.2021.462166]
23. Meifang Wang, Yinping Dong, Jing Wu, Hongyan Li, Yuanyang Zhang, Saijun Fan, Deguan Li.  (2020)  Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.  LIFE SCIENCES,  261  (118463).  [PMID:32950576] [10.1016/j.lfs.2020.118463]
24. Xiaolong Zhang, Qinli Ruan, Yiqian Zhai, Dandan Lu, Chen Li, Yahan Fu, Zihui Zheng, Ying Song, Jun Guo.  (2020)  Baicalein inhibits non-small-cell lung cancer invasion and metastasis by reducing ezrin tension in inflammation microenvironment.  CANCER SCIENCE,  111  (10): (3802-3812).  [PMID:32691974] [10.1111/cas.14577]
25. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song.  (2020)  Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  239  (118519).  [PMID:32480277] [10.1016/j.saa.2020.118519]
26. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang.  (2020)  Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations.  FOOD CHEMISTRY,  323  (126807).  [PMID:32330646] [10.1016/j.foodchem.2020.126807]
27. Liu Xiaojuan, Zhao Chenning, Gong Qin, Wang Yue, Cao Jinping, Li Xian, Grierson Donald, Sun Chongde.  (2020)  Characterization of a caffeoyl-CoA O-methyltransferase-like enzyme involved in biosynthesis of polymethoxylated flavones in Citrus reticulata.  JOURNAL OF EXPERIMENTAL BOTANY,  71  (10): (3066-3079).  [PMID:32182355] [10.1093/jxb/eraa083]
28. Yue Yang, Mingchang Liu, Kai Wang, Yange Yang, Ning Su, Wensheng Huang, Yajun Wu.  (2020)  Chemical and cytological evaluation of honeybee pollen antioxidant ability.  JOURNAL OF FOOD SCIENCE,  85  (3): (824-833).  [PMID:32078757] [10.1111/1750-3841.15047]
29. Xiaojuan Liu, Yue Wang, Yezhi Chen, Shuting Xu, Qin Gong, Chenning Zhao, Jinping Cao, Chongde Sun.  (2020)  Characterization of a Flavonoid 3’/5’/7-O-Methyltransferase from Citrus reticulata and Evaluation of the In Vitro Cytotoxicity of Its Methylated Products.  MOLECULES,  25  (4): (858).  [PMID:32075249] [10.3390/molecules25040858]
30. Zheng-Hong Liu, Cheng-Xi Yang, Lei Zhang, Cong-Ying Yang, Xiu-Quan Xu.  (2019)  Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation.  OncoTargets and Therapy,  12  ( 10749–10761).  [PMID:31849483] [10.2147/OTT.S222819]
31. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu.  (2019)  Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies.  Foods,  8  (9): (355).  [PMID:31438605] [10.3390/foods8090355]
32. Hongjin Chen, Yali Zhang, Wenxin Zhang, Hui Liu, Chuchu Sun, Bing Zhang, Bin Bai, Di Wu, Zhongxiang Xiao, Hazel Lum, Jianmin Zhou, Ruijie Chen, Guang Liang.  (2019)  Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury.  PHYTOMEDICINE,  63  (152997).  [PMID:31254764] [10.1016/j.phymed.2019.152997]
33. Chengyun He, Xiaoling Liu, Junliang Sun.  (2019)  Inhibitory Mechanism of Baicalein Against α-Glucosidase.  Natural Product Communications,  [10.1177/1934578X19855825]
34. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Zhisheng Zhou, Deming Gong.  (2018)  Inhibition mechanism of baicalein and baicalin on xanthine oxidase and their synergistic effect with allopurinol.  Journal of Functional Foods,  50  (172).  [10.1016/j.jff.2018.10.005]
35. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei.  (2018)  Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents.  MOLECULES,  23  (9): (2187).  [PMID:30200208] [10.3390/molecules23092187]
36. Qing-Hui Wen, Lang-Hong Wang, Xin-An Zeng, De-Bao Niu, Man-Sheng Wang.  (2018)  Hydroxyl-related differences for three dietary flavonoids as inhibitors of human purine nucleoside phosphorylase.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  118  (588).  [PMID:29894785] [10.1016/j.ijbiomac.2018.06.045]
37. Xinggui Tian, Huaji Jiang, Yuhui Chen, Xiang Ao, Chuan Chen, Wentao Zhang, Feilin He, Xiaoqing Liao, Xiaocheng Jiang, Tao Li, Zhongmin Zhang, Xintao Zhang.  (2018)  Baicalein Accelerates Tendon-Bone Healing via Activation of Wnt/β-Catenin Signaling Pathway in Rats.  Biomed Research International,  2018  (3849760).  [PMID:29693006] [10.1155/2018/3849760]
38. Dai Chongshan, Tang Shusheng, Wang Yang, Velkov Tony, Xiao Xilong.  (2017)  Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response.  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY,  72  (9): (2562-2569).  [PMID:28859441] [10.1093/jac/dkx185]
39. Zhengkun Xie, Wang Lu, Lingxi Yang, Gaiping Li, Baoxian Ye.  (2017)  A voltammetry sensor platform for baicalein and baicalin simultaneous detection in vivo based on Ta2O5-Nb2O5@CTS composite.  TALANTA,  170  (358).  [PMID:28501181] [10.1016/j.talanta.2017.04.022]
40. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang.  (2017)  Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  140  (384).  [PMID:28347593] [10.1016/j.jpba.2017.03.012]
41. Zhengkun Xie, Gaiping Li, Yamin Fu, Mengjiao Sun, Baoxian Ye.  (2017)  Sensitive, simultaneous determination of chrysin and baicalein based on Ta2O5-chitosan composite modified carbon paste electrode.  TALANTA,  165  (553).  [PMID:28153298] [10.1016/j.talanta.2017.01.021]
42. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan.  (2017)  The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.  FOOD CHEMISTRY,  224  (26).  [PMID:28159264] [10.1016/j.foodchem.2016.12.001]
43. Hongyan He, Ying Huang, Qi Zhang, Jian-Rong Wang, Xuefeng Mei.  (2016)  Zwitterionic Cocrystals of Flavonoids and Proline: Solid-State Characterization, Pharmaceutical Properties, and Pharmacokinetic Performance.  CRYSTAL GROWTH & DESIGN,  16  (4): (2348–2356).  [10.1021/acs.cgd.6b00142]
44. Tingxuan Yan, Yue Cheng, Zhixiang Wang, Dechun Huang, Honggang Miao, Yi Zhang.  (2015)  Preparation and characterization of baicalein powder micronized by the SEDS process.  JOURNAL OF SUPERCRITICAL FLUIDS,  104  (177).  [10.1016/j.supflu.2015.06.005]
45. Ying Zhang, Xuejing Wang, Lei Wang, Miao Yu, Xiaojun Han.  (2014)  Interactions of the baicalin and baicalein with bilayer lipid membranes investigated by cyclic voltammetry and UV–Vis spectroscopy.  BIOELECTROCHEMISTRY,  95  (29).  [PMID:24239871] [10.1016/j.bioelechem.2013.10.008]
46. Ting Wu, Xixi Zang, Mengying He, Siyi Pan, Xiaoyun Xu.  (2013)  Structure–Activity Relationship of Flavonoids on Their Anti-Escherichia coli Activity and Inhibition of DNA Gyrase.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  61  (34): (8185–8190).  [PMID:23926942] [10.1021/jf402222v]

参考文献

1. Lei Liu, Yingyu Sima, Jinxia Feng, Shuting Shi, Aiting Chen, Chuanqin Zhou, Quanguo He, Yimin Tan.  (2024)  Bismuth oxide and nitrogen-doped reduced graphene oxide co-modified glassy carbon electrode to perform sensitive electrochemical sensing and determination of chrysin in pharmaceutical capsules.  MICROCHEMICAL JOURNAL,  196  (109544).  [PMID:1341900] [10.1016/j.microc.2023.109544]
2. Yongbing Xu, Yawen Li, Guilin Chen, Minxia Fan, Guangwan Hu, Mingquan Guo.  (2023)  Screening and identification of potential hypoglycemic and hypolipidemic compounds from aqueous extract of Scutellaria baicalensis Georgi root combing affinity ultrafiltration with multiple drug targets and in silico analysis.  PHYTOCHEMICAL ANALYSIS,  (15): [PMID:37779216] [10.1002/pca.3285]
3. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu.  (2023)  Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.  ACS Applied Materials & Interfaces,  15  (35): (41287–41298).  [PMID:37632730] [10.1021/acsami.3c06996]
4. Shuting Shi, Yanping Wei, Jinxia Feng, Chuanqin Zhou, Jinsong Zuo, Liangyuan Yao, Jianhua Ding, Kanghua Li, Quanguo He.  (2023)  Facile and ultrasensitive electrochemical detection of baicalein on bismuth oxide-carboxylated multi-walled carbon nanotube/glassy carbon electrode.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  123  (105557).  [10.1016/j.jfca.2023.105557]
5. Yufeng Chen, Guobin Xia, Chunfeng Wang, Huawei Wu, Xiaogang Xu, Genxiang Mao, Jiong Wu, Zhenlei Zhao.  (2023)  Impact of dietary plant flavonoids on 7,8-dihydroxyflavone transepithelial transport in human intestinal Caco-2 cells.  Food Science & Nutrition,  [PMID:37970375] [10.1002/fsn3.3581]
6. Xin Liu, Wei Niu, Jiamin Liu, Zhao Cui, Jiazheng Li, Zhenhai Zhang, Jianming Ju.  (2023)  Preparation of β-cyclodextrin and hydroxypropyl-β-cyclodextrin inclusion complexes of baicalein and evaluation of their effects on dextran sulfate sodium-induced acute ulcerative colitis in mice.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  87  (104714).  [10.1016/j.jddst.2023.104714]
7. Liao Zhenkun, Liu Xiaojuan, Zheng Juan, Zhao Chenning, Wang Dengliang, Xu Yang, Sun Chongde.  (2023)  A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus.  PLANT PHYSIOLOGY,  [PMID:37086474] [10.1093/plphys/kiad249]
8. Yameng Liu.  (2023)  Detection of LPS-induced macrophage activation with single-cell resolution through DC insulator-based electrokinetic devices.  ELECTROPHORESIS,  44  (11-12): (978-987).  [PMID:36996424] [10.1002/elps.202200274]
9. Xin-Mei Xie, Jiao-Jiao Hao, Jun-Zhuo Shi, Yun-Feng Zhou, Peng-Fei Liu, Feng Wang, Xiao-Ming Zheng, Xiu-Ying Yu, Chen-Chen Wang, Yi Yan, Guan-Hua Du, Jun-Ke Song, Yang-Yang He, Xiao-Bin Pang.  (2023)  Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.  INTERNATIONAL IMMUNOPHARMACOLOGY,  118  (109994).  [PMID:37098656] [10.1016/j.intimp.2023.109994]
10. Shuoshuo Yang, Guoqi Ni, Mengyang Xia, Hailing Li, Zhonghong Gao.  (2023)  Mussel inspired multifunctional bovine serum albumin (BSA) coatings loaded with Baicalein (BAI) to enhance osteogenesis and resist oxidative stress for potential application on implant.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  229  (752).  [PMID:36586655] [10.1016/j.ijbiomac.2022.12.285]
11. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2023)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,  6  (100424).  [PMID:36618100] [10.1016/j.crfs.2022.100424]
12. Zeng Wanying, Liu Xiaojing, Wu Yangyang, Cai Yuting, Li Zhennan, Ye Fei, Sun Yuanhong, Li Feng, Xing Huijie, Wang Shuai.  (2022)  Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis.  Frontiers in Pharmacology,  13  [PMID:36408246] [10.3389/fphar.2022.1053610]
13. Jingyi Hu, Yiheng Tong, Zhaofeng Shen, Yanan Li, Cheng Cheng, Ryan Au, Feng Xu, Yajun Liu, Lei Zhu, Hong Shen.  (2022)  Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.  BIOMEDICINE & PHARMACOTHERAPY,  154  (113571).  [PMID:36007273] [10.1016/j.biopha.2022.113571]
14. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu.  (2022)  Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system.  Analytical Methods,  14  (37): (3632-3637).  [PMID:36052693] [10.1039/D2AY01019D]
15. Zou Linghui, Zhang Zhongbin, Chen Jinqing, Yang Xu, Li Yuyang, Tang Jing, Du Xiaolu, Tang Ling, Liang Dan, Zhu Xiaoyong, Feng Jianfang, Ding Wenya.  (2022)  β-Cyclodextrin-Grafted Chitosan Enhances Intestinal Drug Absorption and Its Preliminary Mechanism Exploration.  AAPS PHARMSCITECH,  23  (6): (1-11).  [PMID:35948815] [10.1208/s12249-022-02380-z]
16. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372] [10.1039/D1FO03816H]
17. Feng-wei Zhang, Li-yang Peng, Chuan-Jian Shi, Jian-chi Li, Feng-xiang Pang, Wei-ming Fu, Xiao-hua Pan, Jin-fang Zhang.  (2022)  Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis.  Journal of Orthopaedic Translation,  33  (132).  [PMID:35330943] [10.1016/j.jot.2021.12.001]
18. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+.  FOOD CHEMISTRY,  385  (132656).  [PMID:35279499] [10.1016/j.foodchem.2022.132656]
19. Zhao Yan, Hu Jin-Jie, Bai Xiao-Lin, Liu Hao-Peng, Qi Xu-Wei, Liao Xun.  (2022)  Fast screening of tyrosinase inhibitors from traditional Chinese medicinal plants by ligand fishing in combination with in situ fluorescent assay.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  414  (6): (2265-2273).  [PMID:34982177] [10.1007/s00216-021-03864-w]
20. Qingxin Song, Shanxin Peng, Xiaosong Zhu.  (2021)  Baicalein protects against MPP+/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson’s disease.  NEUROTOXICOLOGY,  87  (188).  [PMID:34666128] [10.1016/j.neuro.2021.10.003]
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