| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A420834-1ml |
1ml |
现货  |
|
| 英文别名 | Adenosine Kinase Inhibitor | 1188890-28-9 | ABT 702 dihydrochloride | ABT-702 dihydrochloride | 214697-26-4 | ABT702 2HCl | ABT702 | ABT-702 2HCl | 5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine;dihydrochloride | 5-(3-bromophenyl)-7-(6-mor |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | ABT 702 dihydrochloride |
| 生化机理 | ABT-702 是一种新型、强效的非核苷类腺苷激酶抑制剂，其 IC50 值为 1.7 nM。它在疼痛和炎症动物模型中具有口服活性。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
Information ABT 702 dihydrochloride ABT-702 is a novel, potent non-nucleoside Adenosine kinase inhibitor with an IC50 of 1.7 nM. It has oral activity in animal models of pain and inflammation. Targets adenosine kinase 1.7 nM |
| IUPAC Name | 5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine;dihydrochloride |
|---|---|
| INCHI | InChI=1S/C22H19BrN6O.2ClH/c23-16-3-1-2-14(10-16)17-11-18(28-22-20(17)21(24)26-13-27-22)15-4-5-19(25-12-15)29-6-8-30-9-7-29;;/h1-5,10-13H,6-9H2,(H2,24,26,27,28);2*1H |
| InChi Key | OOXNYFKPOPJIOT-UHFFFAOYSA-N |
| Canonical SMILES | C1COCCN1C2=NC=C(C=C2)C3=NC4=NC=NC(=C4C(=C3)C5=CC(=CC=C5)Br)N.Cl.Cl |
| Isomeric SMILES | C1COCCN1C2=NC=C(C=C2)C3=NC4=NC=NC(=C4C(=C3)C5=CC(=CC=C5)Br)N.Cl.Cl |
| PubChem CID | 16760265 |
| 分子量 | 536.25 |
| 分子量 | 536.200 g/mol |
|---|---|
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 7 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 534.034 Da |
| 单同位素质量Monoisotopic Mass | 534.034 Da |
| 拓扑极表面积Topological Polar Surface Area | 90.100 Ų |
| 重原子数Heavy Atom Count | 32 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 564.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 3 |
| Concentration(Compounding value) | 9.0-11.0(mmol/L) |
|---|---|
| Appearance(Orange Liquid) | Pass |
| Record the entire process by video | Conform |
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