计算溶液所需的质量、体积或浓度。
活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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A111884-1g |
1g |
期货 ![]() |
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A111884-5g |
5g |
现货 ![]() |
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A111884-25g |
25g |
现货 ![]() |
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A111884-100g |
100g |
现货 ![]() |
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A111884-500g |
500g |
现货 ![]() |
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别名 | 5'-磷酸腺苷,AMP | 5'-腺苷酸 |
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英文别名 | F85584 | MLS001306420 | 9-(5-O-Phosphonopentofuranosyl)-9H-purin-6-amine--water (1/1) | A812845 | SR-01000837507 | PCB No 105 | ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate hydrate | SCHEMBL968911 |
规格或纯度 | ≥97%, from yeast |
英文名称 | Adenosine 5'-monophosphate monohydrate |
生化机理 | 5′-单磷酸腺苷(5′-AMP)本身具有许多用途。5′-AMP是一类称为AMP活化蛋白激酶(AMPK)的蛋白激酶的激活剂。AMP可抑制AMPK去磷酸化,促进上游激酶对AMPK磷酸化。 |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 |
5′-单磷酸腺苷(5′-AMP)适合用作:合成腺苷-5′-磷酰咪唑啉的试剂;合成支链多糖的聚合反应中磷酸化酶b的活化剂;内源性NMN腺苷酰转移酶(NMNAT,将NMN转化成NAD+)的活性抑制剂。
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作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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PubChem SID | 488195746 |
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分子类型 | 小分子 |
IUPAC Name | [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;hydrate |
INCHI | InChI=1S/C10H14N5O7P.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1H2/t4-,6-,7-,10-;/m1./s1 |
InChi Key | ZOEFQKVADUBYKV-MCDZGGTQSA-N |
Canonical SMILES | O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP(O)(O)=O.O |
Isomeric SMILES | C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N.O |
WGK Germany | 3 |
PubChem CID | 6419976 |
分子量 | 365.24 |
Beilstein号 | 54612 |
溶解性 | solubility 1 M NH4OH: soluble 50 mg/mL, clear, colorless H2O: soluble (with addition of mild alkali) |
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密度 | 0.85 |
熔点 | 183-188°C |
分子量 | 365.240 g/mol |
XLogP3 | |
氢键供体数Hydrogen Bond Donor Count | 6 |
氢键受体数Hydrogen Bond Acceptor Count | 12 |
可旋转键计数Rotatable Bond Count | 4 |
精确质量Exact Mass | 365.074 Da |
单同位素质量Monoisotopic Mass | 365.074 Da |
拓扑极表面积Topological Polar Surface Area | 187.000 Ų |
重原子数Heavy Atom Count | 24 |
形式电荷Formal Charge | 0 |
复杂度Complexity | 481.000 |
同位素原子数Isotope Atom Count | 0 |
定义的原子立体中心计数Defined Atom Stereocenter Count | 4 |
未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
所有立体化学键的总数The total count of all stereochemical bonds | 0 |
共价键合单元计数Covalently-Bonded Unit Count | 2 |
WGK Germany | 3 |
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Purity(HPLC) | 97-100(%) |
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Specific Rotation [a]20/D(c=2 in 2% NaOH | -49.5--47.5(°) |
Water by Karl Fischer | 3.5-6.2(%) |
Appearance(A111884) | white powder |
Solubility,Colorless ,Clear 50 mg/mL, 1M NH4OH | pass |
LC-MS for identification | Conforms |
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批号(Lot Number) | 证书类型 | 日期 | 货号 |
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分析证书 | 25-03-04 | A111884 |
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分析证书 | 24-09-07 | A111884 |
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分析证书 | 24-09-07 | A111884 |
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分析证书 | 24-09-07 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-11-23 | A111884 |
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分析证书 | 22-01-04 | A111884 |
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分析证书 | 22-01-04 | A111884 |
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分析证书 | 22-01-04 | A111884 |
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分析证书 | 22-01-04 | A111884 |
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分析证书 | 22-01-04 | A111884 |
¥205.90
1. Tiantian Tang, Min Zhang, Yaping Liu. (2023) Valorization of meat and bone residue by ultrasound and high voltage electrostatic field assisted two-stage enzymatic hydrolysis: Nutritional characteristics and flavor analysis. Food Bioscience, 56 (6): (103203). [PMID:25561738] [10.1016/j.fbio.2023.103203] |
2. Huifang Wu, Shiying Ju, Yuwei Ling, Haozhe Sun, Yanfeng Tang, Changlun Tong. (2023) Gelatinous lanthanide coordination polymer with aggregation-enhanced antenna effect for ratiometric detection of endogenous alkaline phosphatase. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 645 (338). [PMID:37150007] [10.1016/j.jcis.2023.04.147] |
3. Li Qianjin, Wang Tingting, Hou Yadan, Wang Dan, Xiong Shuqing, Wei Chenhong, Cao Qianyong, Wang Fenying. (2023) Solid-Phase Extraction and Simultaneous Fluorescence Detection of Cis-Diol-Containing Biomolecules Based on a Novel Boronate Affinity Material. CHROMATOGRAPHIA, 86 (5): (387-399). [10.1007/s10337-023-04252-5] |
4. Jianghong Wu, Min Zhang, Lihui Zhang, Yaping Liu. (2022) Effect of ultrasound combined with sodium bicarbonate pretreatment on the taste and flavor of chicken broth. JOURNAL OF FOOD PROCESS ENGINEERING, 46 (6): (e14072). [10.1111/jfpe.14072] |
1. Tiantian Tang, Min Zhang, Yaping Liu. (2023) Valorization of meat and bone residue by ultrasound and high voltage electrostatic field assisted two-stage enzymatic hydrolysis: Nutritional characteristics and flavor analysis. Food Bioscience, 56 (6): (103203). [PMID:25561738] [10.1016/j.fbio.2023.103203] |
2. Huifang Wu, Shiying Ju, Yuwei Ling, Haozhe Sun, Yanfeng Tang, Changlun Tong. (2023) Gelatinous lanthanide coordination polymer with aggregation-enhanced antenna effect for ratiometric detection of endogenous alkaline phosphatase. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 645 (338). [PMID:37150007] [10.1016/j.jcis.2023.04.147] |
3. Li Qianjin, Wang Tingting, Hou Yadan, Wang Dan, Xiong Shuqing, Wei Chenhong, Cao Qianyong, Wang Fenying. (2023) Solid-Phase Extraction and Simultaneous Fluorescence Detection of Cis-Diol-Containing Biomolecules Based on a Novel Boronate Affinity Material. CHROMATOGRAPHIA, 86 (5): (387-399). [10.1007/s10337-023-04252-5] |
4. Jianghong Wu, Min Zhang, Lihui Zhang, Yaping Liu. (2022) Effect of ultrasound combined with sodium bicarbonate pretreatment on the taste and flavor of chicken broth. JOURNAL OF FOOD PROCESS ENGINEERING, 46 (6): (e14072). [10.1111/jfpe.14072] |