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芦荟大黄素

凋亡抗癌药
13篇引用文献
  • ≥95%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
A111278-25mg
 25mg 现货 Stock Image
A111278-100mg
 100mg 现货 Stock Image
A111278-250mg
 250mg 期货 Stock Image
A111278-500mg
 500mg 现货 Stock Image
A111278-1g
 1g 期货 Stock Image
A111278-5g
 5g 现货 Stock Image
A111278-25g
 25g 期货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
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六元碳环化合物 (245) 蒽醌类 (59)
main product photo

基本描述

别名 芦荟泻素
英文别名 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- | Aloeemodin | Aloe-emodin | Aloe-emodin, analytical standard | Q-100526 | MLS000697563 | s2259 | CCG-208456 | SR-01000765772-3 | 3-(Hydroxymethyl)chrysazin | 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-h
规格或纯度 ≥95%
英文名称 Aloe-emodin
生化机理 泻药/泻药化合物；通过释放内源性乙酰胆碱增加肠道平滑肌的收缩。抗肿瘤活性与活性氧（ROS）的产生增加有关，ROS 的产生反过来又会降低线粒体跨膜电位，从而诱发通透性转换，引发一系列事件，最终导致细胞凋亡。基因毒性和诱变性似乎是由于芦荟大黄素抑制了拓扑异构酶 II 的活性。AChE 抑制剂（IC 50 = 68 μM）。调节氧化应激。通过抑制 ERα 显示抗增殖作用。在体内具有神经保护和抗肿瘤作用。
储存温度 2-8°C储存
运输条件 冰袋运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

易溶于热乙醇，在苯及乙醚中呈黄色，在氨水和硫酸中呈绯红色，属蒽醌类化合物，在酸性溶液中被还原则生成蒽酚及其互变异构体的蒽酮。 泻药/泻剂化合物;内源性乙酰胆碱的释放增加了肠道平滑肌收缩。遗传毒性和致突变性似乎是由芦荟大黄素由于抑制拓扑异构酶II活性

AI解读

关联靶点（人）

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P2RY12 Tclin Purinergic receptor P2Y12 (2369 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ELANE Tclin Leukocyte elastase (8173 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CTSG Tchem Cathepsin G (2304 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EPHX2 Tchem Epoxide hydratase (3844 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALPG Tchem Alkaline phosphatase placental-like (1197 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A498 (42825 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHN (49357 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CAKI-1 (44928 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DLD-1 (17511 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DMS-273 (14108 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KM12 (47707 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
M14 (47487 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MOLT-4 (49676 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-3 (48710 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-4 (44535 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-5 (45555 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RPMI-8226 (44974 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXF 393 (41971 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXF 631 (11415 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SF-295 (48000 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-2 (46422 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-28 (48833 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-5 (47095 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-OV-3 (52876 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SN12C (47755 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SNB-19 (46794 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SNB-78 (14240 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TK-10 (45540 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U-251 (51189 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UACC-257 (46019 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
XF498 (12972 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A-431 (6446 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI-H322M (45589 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HCC 2998 (41480 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Alpha-chymotrypsin (819 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ttr Transthyretin (14 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CELA2A Elastase 2A (403 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Iap Intestinal alkaline phosphatase (419 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Streptococcus mutans (2687 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Phytophthora infestans (820 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterococcus faecalis (29875 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fusarium oxysporum (3998 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis B virus (7925 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Man1 Alpha-mannosidase (188 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
B16-F10 (4610 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FUCA1 Alpha-L-fucosidase 1 (358 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd2 Thioredoxin reductase 2, mitochondrial (18 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 (5 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Erwinia amylovora (182 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Estrogen receptor (4 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fusarium graminearum (1554 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488181089
EC号 207-571-7
分子类型 小分子
IUPAC Name 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
INCHI InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
InChi Key YDQWDHRMZQUTBA-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
Isomeric SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
WGK Germany 3
RTECS CB6712200
PubChem CID 10207
分子量 270.24
Beilstein号 2059062

化学和物理性质

密度 1.592
敏感性 对热敏感
熔点 223-224°C
分子量 270.240 g/mol
XLogP3 1.800
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 270.053 Da
单同位素质量Monoisotopic Mass 270.053 Da
拓扑极表面积Topological Polar Surface Area 94.800 Ų
重原子数Heavy Atom Count 20
形式电荷Formal Charge 0
复杂度Complexity 420.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
RTECS CB6712200
Merck Index 306
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

 SDS英文版

技术规格说明书

Purity(HPLC) 97-100（%）
Melting point 220-224（℃）
Appearance（A111278) Yellow to Brown Powder or Crystals
Proton NMR spectrum Conforms to Structure
Solubility in DMSO，Light Red to Orange to Brown，50 mg/ml Conforms

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到17个结果

批号(Lot Number) 证书类型 日期 货号
K2414100 分析证书 24-11-19 A111278
D2424088 分析证书 24-03-09 A111278
D2424089 分析证书 24-03-09 A111278
B2420036 分析证书 24-02-27 A111278
H2401015 分析证书 24-02-27 A111278
J2211616 分析证书 23-05-25 A111278
J2211620 分析证书 23-05-25 A111278
J2211634 分析证书 23-05-25 A111278
J2211659 分析证书 23-05-25 A111278
J2211676 分析证书 23-05-25 A111278
E1921029 分析证书 23-03-08 A111278
B2325258 分析证书 23-03-02 A111278
B2325259 分析证书 23-03-02 A111278
K1826043 分析证书 22-09-16 A111278
J1819038 分析证书 22-08-10 A111278
K2110548 分析证书 21-11-17 A111278
B2325257 分析证书 21-11-17 A111278

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13. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun.  (2014)  Effects of several quinones on insulin aggregation.  Scientific Reports,  4  (1): (1-8).  [PMID:25008537] [10.1038/srep05648]

参考文献

1. Baqi Y, Atzler K, Köse M, Glänzel M, Müller CE.  (2009)  High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors..  J Med Chem,  52  (12): (3784-93).  [PMID:19463000] [10.1021/op500134e]
2. Tom Coenye,Kris Honraet,Petra Rigole,Pol Nadal Jimenez,Hans J Nelis.  (2007-01-16)  In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones..  Antimicrobial agents and chemotherapy,  51  ((4)): (1541-1544).  [PMID:17220400]
3. Xing-Ri Cui,Maiko Tsukada,Nao Suzuki,Takeshi Shimamura,Li Gao,Jyunichi Koyanagi,Fusao Komada,Setsuo Saito.  (2007-10-24)  Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones..  European journal of medicinal chemistry,  43  ((6)): (1206-1215).  [PMID:17949858]
4. Junko Koyama,Yu Nisino,Izumi Morita,Norihiro Kobayashi,Toshiyuki Osakai,Harukuni Tokuda.  (2008-06-17)  Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives..  Bioorganic & medicinal chemistry letters,  18  ((14)): (4106-4109).  [PMID:18556196]
5. Francesca Sorrentino,Anastasia Karioti,Paola Gratteri,Maria Pia Rigobello,Guido Scutari,Luigi Messori,Alberto Bindoli,Matteo Chioccioli,Chiara Gabbiani,Maria Camilla Bergonzi,Anna Rita Bilia.  (2010-11-26)  Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones..  Bioorganic & medicinal chemistry,  19  ((1)): (631-641).  [PMID:21106380]
6. Khalilah Haris,Samhani Ismail,Zamzuri Idris,Jafri Malin Abdullah,Abdul Aziz Mohamed Yusoff.  (2014-06-28)  Expression profile of genes modulated by Aloe emodin in human U87 glioblastoma cells..  Asian Pacific journal of cancer prevention : APJCP,  15  ((11)): (4499-4505).  [PMID:24969876]
7. Naraganahalli R Thimmegowda,Chanmi Park,Bettaswamigowda Shwetha,Krisada Sakchaisri,Kangdong Liu,Joonsung Hwang,Sangku Lee,Sook J Jeong,Nak K Soung,Jae H Jang,In-Ja Ryoo,Jong S Ahn,Raymond L Erikson,Bo Y Kim.  (2014-10-18)  Synthesis and antitumor activity of natural compound aloe emodin derivatives..  Chemical biology & drug design,  85  ((5)): (638-644).  [PMID:25323822]
8. Mildred Acevedo-Duncan,Christopher Russell,Sapna Patel,Rekha Patel.  (2004-11-09)  Aloe-emodin modulates PKC isozymes, inhibits proliferation, and induces apoptosis in U-373MG glioma cells..  International immunopharmacology,  4  ((14)): (1775-1784).  [PMID:15531293]
9. Xia Zhou,Baoan Song,Linhong Jin,Deyu Hu,Chunling Diao,Guangfang Xu,Zhihui Zou,Song Yang.  (2005-11-09)  Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb..  Bioorganic & medicinal chemistry letters,  16  ((3)): (563-568).  [PMID:16275083]
10. Jun-ming Guo,Bing-xiu Xiao,Qiong Liu,Shun Zhang,Dong-hai Liu,Zhao-hui Gong.  (2007-11-23)  Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation..  Acta pharmacologica Sinica,  28  ((12)): (1991-1995).  [PMID:18031614]
11. Yiqun Du,Jian Zhang,Zhonghua Tao,Chenchen Wang,Shiyan Yan,Xiaowei Zhang,Mingzhu Huang.  (2019-05-28)  Aloe emodin exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential (ΛΨm)..  Journal of B.U.ON. : official journal of the Balkan Union of Oncology,  24  ((2)): (746-753).  [PMID:31128032]
12. Wenbin Chen, Airi N. Kato, Lijun Dai, Paul S. Clegg, Tao Li.  (2023)  Continuous Emulsion Channels Achieved by Controlling the Aqueous–Oil Interface Solely with Rough Colloids.  ADVANCED FUNCTIONAL MATERIALS,  34  (6): (2308608).  [PMID:9647693] [10.1002/adfm.202308608]
13. Mengsi Zhang, Lu Wang, Hao Jin, Nan Zhao, Yi Liu, Shijie Lan, Shuwei Liu, Hao Zhang.  (2023)  Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.  JOURNAL OF CONTROLLED RELEASE,  358  (612).  [PMID:37196899] [10.1016/j.jconrel.2023.05.020]
14. Huijie Gao, Yan Ren, Chao Liu.  (2022)  Aloe-Emodin Suppresses Oxidative Stress and Inflammation via a PI3K-Dependent Mechanism in a Murine Model of Sepsis.  Evidence-based Complementary and Alternative Medicine,  2022  (9697887).  [PMID:35978995] [10.1155/2022/9697887]
15. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu.  (2022)  2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae.  RESEARCH IN MICROBIOLOGY,  173  (103955).  [PMID:35550403] [10.1016/j.resmic.2022.103955]
16. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu.  (2022)  Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis.  Frontiers in Pharmacology,  13  (842720).  [PMID:35392552] [10.3389/fphar.2022.842720]
17. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo.  (2022)  Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA.  Foods,  11  (3): (386).  [PMID:35159536] [10.3390/foods11030386]
18. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang.  (2020)  Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L..  MICROCHEMICAL JOURNAL,  152  (104245).  [10.1016/j.microc.2019.104245]
19. Qingqing Hao, Lilin Lu, Xianwen Kan.  (2019)  Probe and analogue: Double roles of thionine for aloe-emodin selective and sensitive ratiometric detection.  SENSORS AND ACTUATORS B-CHEMICAL,  292  (247).  [10.1016/j.snb.2019.04.129]
20. Jian Lu, Yingying Qin, Qi Zhang, Chao Yu, Yilin Wu, Yongsheng Yan, Hougang Fan, Minjia Meng, Chunxiang Li.  (2019)  Antibacterial, high-flux and 3D porous molecularly imprinted nanocomposite sponge membranes for cross-flow filtration of emodin from analogues.  CHEMICAL ENGINEERING JOURNAL,  360  (483).  [10.1016/j.cej.2018.12.014]
21. Wang Qianqian, Xu Yixiang, Xu Jiaqi, Wang Xudong, Shen Chen, Zhang Yan, Liu Xiufeng, Yu Boyang, Zhang Jian.  (2017)  Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols.  BIOTECHNOLOGY LETTERS,  39  (8): (1229-1235).  [PMID:28484911] [10.1007/s10529-017-2352-z]
22. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan.  (2017)  Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L..  JOURNAL OF APPLIED POLYMER SCIENCE,  134  (21): [10.1002/app.44874]
23. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun.  (2015)  Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea.  JOURNAL OF SEPARATION SCIENCE,  38  (8): (1263-1270).  [PMID:25677958] [10.1002/jssc.201401341]
24. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun.  (2014)  Effects of several quinones on insulin aggregation.  Scientific Reports,  4  (1): (1-8).  [PMID:25008537] [10.1038/srep05648]

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