计算溶液所需的质量、体积或浓度。
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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A105386-5g |
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A105386-10g |
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A105386-25g |
25g |
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A105386-100g |
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A105386-500g |
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别名 | 别嘌呤醇 | 4-羟基吡唑并[3,4-d]嘧啶 | 1H-吡唑并[3,4-d]嘧啶-4-醇 |
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英文别名 | HPP | 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro- | Dabrosin | DTXSID50892275 | Xanturat | 4-Hydroxypyrazolyl(3,4-d)pyrimidine | O11481 | Zyloric | 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one | 1H-pyrazolo[3,4-d]pyrimidin-4(2H)-one | 4-Hydroxypyrazo |
规格或纯度 | Moligand™, ≥98% |
英文名称 | Allopurinol |
生化机理 | 黄嘌呤氧化酶抑制剂(IC 50 = 0.2-50μM)。抗高尿酸嘌呤类似物。抑制体内尿酸的产生。具有神经保护作用。体内具有活性 |
运输条件 | 常规运输 |
作用类型 | 抑制剂 |
作用机制 | 黄嘌呤脱氢酶抑制剂 |
备注 | 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。有毒,请参阅SDS以获取更多信息。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
产品介绍 |
Allopurinol is an anti-urolithic Xanthine oxidase inhibitor that decreases uric acid production.黄嘌呤氧化酶(xanthine oxidase) 和吡啶合成的抑制剂。 Allopurinol is an anti-urolithic Xanthine oxidase inhibitor that decreases uric acid production. |
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作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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PubChem SID | 504773260 |
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EC号 | 206-250-9 |
分子类型 | 小分子 |
IUPAC Name | 1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one |
INCHI | InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10) |
InChi Key | OFCNXPDARWKPPY-UHFFFAOYSA-N |
Canonical SMILES | C1=NNC2=C1C(=O)NC=N2 |
Isomeric SMILES | C1=NNC2=C1C(=O)NC=N2 |
WGK Germany | 2 |
RTECS | UR0785000 |
PubChem CID | 135401907 |
UN Number | 2811 |
Packing Group | I |
分子量 | 136.11 |
Beilstein号 | 26(3/4)4298 |
Reaxy-Rn | 608611 |
溶解性 | 不溶于水;水中溶解度:0.48 g/l 25 °C;不溶于氯仿、乙醚、乙醇;1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow |
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密度 | 1.89 |
熔点 | 384°C |
分子量 | 136.110 g/mol |
XLogP3 | -0.700 |
氢键供体数Hydrogen Bond Donor Count | 2 |
氢键受体数Hydrogen Bond Acceptor Count | 3 |
可旋转键计数Rotatable Bond Count | 0 |
精确质量Exact Mass | 136.039 Da |
单同位素质量Monoisotopic Mass | 136.039 Da |
拓扑极表面积Topological Polar Surface Area | 70.100 Ų |
重原子数Heavy Atom Count | 10 |
形式电荷Formal Charge | 0 |
复杂度Complexity | 190.000 |
同位素原子数Isotope Atom Count | 0 |
定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
所有立体化学键的总数The total count of all stereochemical bonds | 0 |
共价键合单元计数Covalently-Bonded Unit Count | 1 |
象形图 | GHS06, GHS07 |
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信号词 | Danger |
危险声明 |
H301: 吞咽会中毒 H317: 可能引起皮肤过敏反应 |
预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。 |
WGK Germany | 2 |
RTECS | UR0785000 |
Reaxy-Rn | 608611 |
Class | 6.1 |
Merck Index | 279 |
个人防护装备 | Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges |
Carbon by Elemental Analysis | 43.1-45.3(%) |
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Purity(HPLC) | 98-100(%) |
Purity(Neutralization titration) | 97.5-102.5(%) |
Nitrogen by Elemental Analysis | 40.1-42.1(%) |
Appearance(A105386) | White to Off-White Powder |
Infrared spectrum | Conforms to Structure |
Proton NMR spectrum | Conforms to Structure |
Solubility in 1M NaOH,Colorless to Yellow,Clear to Slightly Hazy,50mg/ml | pass |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
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分析证书 | 21-11-02 | A105386 |
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分析证书 | 21-11-02 | A105386 |
¥475.90
1. Jiana Du, Na Wang, Dehong Yu, Pei He, Yu Gao, Yanbei Tu, Yanfang Li. (2023) Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters. PHYTOMEDICINE, (155305). [PMID:38176275] [10.1016/j.phymed.2023.155305] |
2. Jie Xiong, Ya-ying Wang, Muhammad Yousaf, Dong-mei Liu. (2023) Improvement of Physicochemical Properties and Flavor of Pickled Radish through the Use of a Direct-Vat Set Starter Consisting of Lactiplantibacillus Plantarum and Leuconostoc Mesenteroides. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, [PMID:21153684] [10.1111/ijfs.16731] |
3. Yawen Wang, Longjian Zhou, Minqi Chen, Yayue Liu, Yu Yang, Tiantian Lu, Fangfang Ban, Xueqiong Hu, Zhongji Qian, Pengzhi Hong, Yi Zhang. (2023) Mining Xanthine Oxidase Inhibitors from an Edible Seaweed Pterocladiella capillacea by Using In Vitro Bioassays, Affinity Ultrafiltration LC-MS/MS, Metabolomics Tools, and In Silico Prediction. Marine Drugs, 21 (10): (502). [PMID:37888437] [10.3390/md21100502] |
4. Xueqin Wang, Zhenzhen Cui, Yuan Luo, Yu Huang, Xinbin Yang. (2023) In vitro xanthine oxidase inhibitory and in vivo anti-hyperuricemic properties of sodium kaempferol-3′-sulfonate. FOOD AND CHEMICAL TOXICOLOGY, 177 (113854). [PMID:37230458] [10.1016/j.fct.2023.113854] |
5. Jiling Song, Minghui Chen, Fanlei Meng, Jiahui Chen, Zhanwei Wang, Yong Zhang, Jing Cui, Jing Wang, Dongfang Shi. (2023) Studies on the interaction mechanism between xanthine oxidase and osmundacetone: Molecular docking, multi-spectroscopy and dynamical simulation. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 299 (122861). [PMID:37209475] [10.1016/j.saa.2023.122861] |
6. Jianmin Chen, Zemin He, Sijin Yu, Xiaozhen Cai, Danhong Zhu, Yanhua Lin. (2023) Xanthine oxidase inhibitory kinetics and mechanism of ellagic acid: In vitro, in silico and in vivo studies. IET Nanobiotechnology, 17 (4): (368-375). [PMID:37153957] [10.1049/nbt2.12135] |
7. Yi-Fang Gao, Meng-Qi Liu, Zhong-Han Li, Han-Lin Zhang, Jia-Qi Hao, Bo-Hao Liu, Xiao-Yan Li, Yu-Qi Yin, Xiao-Hui Wang, Qian Zhou, Di Xu, Bao-Ming Shi, Ying-Hua Zhang. (2023) Purification and identification of xanthine oxidase inhibitory peptides from enzymatic hydrolysate of α-lactalbumin and bovine colostrum casein. FOOD RESEARCH INTERNATIONAL, 169 (112882). [PMID:37254330] [10.1016/j.foodres.2023.112882] |
8. Jinhua Li, Namrta Choudhry, Gang Lv, Naganna Nimishetti, Mallu Chenna Reddy, Hong Liu, Thaddeus D. Allen, Jing Zhang, Dun Yang. (2023) In-vitro metabolism of LXY18, an orally available, potent blocker of AURKB relocation in mitosis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 232 (115415). [PMID:37120975] [10.1016/j.jpba.2023.115415] |
9. Jiling Song, Zhanwei Wang, Yu Chi, Yong Zhang, Chenyi Fang, Yuting Shu, Jing Cui, Helong Bai, Jing Wang. (2023) Anti-gout activity and the interaction mechanisms between Sanghuangporus vaninii active components and xanthine oxidase. BIOORGANIC CHEMISTRY, 133 (106394). [PMID:36801789] [10.1016/j.bioorg.2023.106394] |
10. Yingling Sui, Deping Xu, Xiulan Sun. (2023) Identification of anti-hyperuricemic components from Coix seed. Food Bioscience, 52 (102461). [10.1016/j.fbio.2023.102461] |
11. Rui Wang, Han Wang, Guohua Jiang, Yanfang Sun, Tianqi Liu, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Uladzislau E. Aharodnikau, Sergey O. Solomevich. (2023) Transdermal delivery of allopurinol to acute hyperuricemic mice via polymer microneedles for the regulation of serum uric acid levels. Biomaterials Science, 11 (5): (1704-1713). [PMID:36628631] [10.1039/D2BM01836E] |
12. Yin Wan, Dengxiao Wang, Yuefeng Shen, Yanru Chen, Jin Qian, Guiming Fu. (2022) Effect of Lactobacillus acidophilus fermentation on the composition of chlorogenic acids and anti-hyperuricemia activity of Artemisia selengensis Turcz. Food & Function, 13 (22): (11780-11793). [PMID:36300542] [10.1039/D2FO01854C] |
13. Gao Tianshu, Xu Jin, Xiao Yuxiao, Li Jiaqi, Hu Weifeng, Su Xiaoyu, Shen Xudong, Yu Wan, Chen Zhen, Huang Baosheng, Li Honglei, Wang Xing. (2022) Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia. Frontiers in Pharmacology, 13 [PMID:36120294] [10.3389/fphar.2022.950699] |
14. Yawen Lian, Xiang Yuan, Yandan Wang, Lin Wei. (2022) Highly sensitive visual colorimetric sensor for xanthine oxidase detection by using MnO2-nanosheet-modified gold nanoparticles. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 276 (121219). [PMID:35397450] [10.1016/j.saa.2022.121219] |
15. Rui Sun, Juan Kan, Huahao Cai, Jinhai Hong, Changhai Jin, Man Zhang. (2022) In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia. JOURNAL OF FOOD BIOCHEMISTRY, 46 (2): (e14049). [PMID:34981522] [10.1111/jfbc.14049] |
16. Liyan Yuan, Zhijie Bao, Tiecheng Ma, Songyi Lin. (2021) Hypouricemia effects of corn silk flavonoids in a mouse model of potassium oxonated-induced hyperuricemia. JOURNAL OF FOOD BIOCHEMISTRY, 45 (8): (e13856). [PMID:34250618] [10.1111/jfbc.13856] |
17. Yin Wan, Jin Qian, Yizhen Li, Yuefeng Shen, Yanru Chen, Guiming Fu, Mingyong Xie. (2021) Inhibitory mechanism of xanthine oxidase activity by caffeoylquinic acids in vitro. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 184 (843). [PMID:34146563] [10.1016/j.ijbiomac.2021.06.075] |
18. Caixin Ni, Xin Li, Linlin Wang, Xiu Li, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen. (2021) Lactic acid bacteria strains relieve hyperuricaemia by suppressing xanthine oxidase activity via a short-chain fatty acid-dependent mechanism. Food & Function, 12 (15): (7054-7067). [PMID:34152353] [10.1039/D1FO00198A] |
19. Shi Feng, Chen Lin, Wang Yaping, Liu Jing, Adu-Frimpong Michael, Ji Hao, Toreniyazov Elmurat, Wang Qilong, Yu Jiangnan, Xu Ximing. (2022) Enhancement of oral bioavailability and anti-hyperuricemic activity of aloe emodin via novel Soluplus®—glycyrrhizic acid mixed micelle system. Drug Delivery and Translational Research, 12 (3): (603-614). [PMID:33860450] [10.1007/s13346-021-00969-8] |
20. Xie Jiahong, Cui Haoxin, Xu Yang, Xie Lianghua, Chen Wei. (2021) Delphinidin-3-O-sambubioside: a novel xanthine oxidase inhibitor identified from natural anthocyanins. Food Quality and Safety, 5 [10.1093/fqsafe/fyaa038] |
21. Qian Zhou, Jia-Yi Yin, Wei-Yue Liang, Dong-Mei Chen, Qing Yuan, Bao-long Feng, Ying-Hua Zhang, Yu-Tang Wang. (2021) Various machine learning approaches coupled with molecule simulation in the screening of natural compounds with xanthine oxidase inhibitory activity. Food & Function, 12 (4): (1580-1589). [PMID:33470259] [10.1039/D0FO03059G] |
22. Yanzuo Le, Xie Zhou, Jiawen Zheng, Fangmiao Yu, Yunping Tang, Zuisu Yang, Guofang Ding, Yan Chen. (2020) Anti-Hyperuricemic Effects of Astaxanthin by Regulating Xanthine Oxidase, Adenosine Deaminase and Urate Transporters in Rats. Marine Drugs, 18 (12): (610). [PMID:33271765] [10.3390/md18120610] |
23. Yi Tao, Lin Chen, Enci Jiang. (2021) Layer-by-layer assembly strategy for fabrication of polydopamine-polyethyleneimine hybrid modified fibers and their application to solid-phase microextraction of bioactive molecules from medicinal plant samples followed by surface plasmon resonance biosensor validation. ANALYTICA CHIMICA ACTA, 1146 (155). [PMID:33461711] [10.1016/j.aca.2020.11.016] |
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25. Xiao-Wei Zhang, Mei Zhou, Lin An, Ping Zhang, Ping Li, Jun Chen. (2020) Lipophilic Extract and Tanshinone IIA Derived from Salvia miltiorrhiza Attenuate Uric Acid Nephropathy through Suppressing Oxidative Stress-Activated MAPK Pathways. AMERICAN JOURNAL OF CHINESE MEDICINE, 48 (6): (1455-1473). [PMID:32933312] [10.1142/S0192415X20500718] |
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27. Zhang Kangyi, Wang Qilong, Yang Qiuxuan, Wei Qiuyu, Man Na, Adu-Frimpong Michael, Toreniyazov Elmurat, Ji Hao, Yu Jiangnan, Xu Ximing. (2019) Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System. AAPS PHARMSCITECH, 20 (5): (1-11). [PMID:31187334] [10.1208/s12249-019-1421-0] |
28. Yin Wan, Fen Wang, Bin Zou, Yuefeng Shen, Yizhen Li, Axi Zhang, Guiming Fu. (2019) Molecular mechanism underlying the ability of caffeic acid to decrease uric acid levels in hyperuricemia rats. Journal of Functional Foods, 57 (150). [10.1016/j.jff.2019.03.038] |
29. Tianqiao Yong, Shaodan Chen, Yizhen Xie, Diling Chen, Jiyan Su, Ou Shuai, Huiping Hu, Dan Zuo, Danling Liang. (2018) Hypouricemic Effects of Armillaria mellea on Hyperuricemic Mice Regulated through OAT1 and CNT2. AMERICAN JOURNAL OF CHINESE MEDICINE, 46 (3): (585-599). [PMID:29595077] [10.1142/S0192415X18500301] |
30. Yin Wan, Yu-Xi Liang, Bin Zou, Gui-Ming Fu, Ming-Yong Xie. (2018) The possible mechanism of hydroxytyrosol on reducing uric acid levels. Journal of Functional Foods, 42 (319). [10.1016/j.jff.2018.01.009] |
31. Jing Wang, Dongfang Shi, Meizhu Zheng, Bing Ma, Jing Cui, Chunming Liu, Chengyu Liu. (2017) Screening, separation, and evaluation of xanthine oxidase inhibitors from Paeonia lactiflora using chromatography combined with a multi-mode microplate reader. JOURNAL OF SEPARATION SCIENCE, 40 (21): (4160-4167). [PMID:28857450] [10.1002/jssc.201700690] |
32. Zeynep Tohtahon, Lu Zhang, Jianxin Han, Xing Xie, Zongcai Tu, Tao Yuan. (2017) Extraction optimization, structural characterization and bioactivity evaluation of triterpenoids from hawthorn (Crataegus cuneata) fruits. JOURNAL OF FOOD BIOCHEMISTRY, 41 (4): (e12377). [10.1111/jfbc.12377] |
33. Hongjin Tang, Lin Yang, Wei Li, Jiahuang Li, Jun Chen. (2016) Exploring the interaction between Salvia miltiorrhiza and xanthine oxidase: insights from computational analysis and experimental studies combined with enzyme channel blocking. RSC Advances, 6 (114): (113527-113537). [10.1039/C6RA24396G] |
34. Yin Wan, Bin Zou, Hailong Zeng, Lunning Zhang, Ming Chen, Guiming Fu. (2016) Inhibitory effect of verbascoside on xanthine oxidase activity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 93 (609). [PMID:27616694] [10.1016/j.ijbiomac.2016.09.022] |
35. Fu Yu, Mo Hua-Yan, Gao Wen, Hong Jia-Ying, Lu Jun, Li Ping, Chen Jun. (2014) Affinity selection-based two-dimensional chromatography coupled with high-performance liquid chromatography-mass spectrometry for discovering xanthine oxidase inhibitors from Radix Salviae Miltiorrhizae. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 406 (20): (4987-4995). [PMID:24866714] [10.1007/s00216-014-7902-9] |
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23. Yanzuo Le, Xie Zhou, Jiawen Zheng, Fangmiao Yu, Yunping Tang, Zuisu Yang, Guofang Ding, Yan Chen. (2020) Anti-Hyperuricemic Effects of Astaxanthin by Regulating Xanthine Oxidase, Adenosine Deaminase and Urate Transporters in Rats. Marine Drugs, 18 (12): (610). [PMID:33271765] [10.3390/md18120610] |
24. Yi Tao, Lin Chen, Enci Jiang. (2021) Layer-by-layer assembly strategy for fabrication of polydopamine-polyethyleneimine hybrid modified fibers and their application to solid-phase microextraction of bioactive molecules from medicinal plant samples followed by surface plasmon resonance biosensor validation. ANALYTICA CHIMICA ACTA, 1146 (155). [PMID:33461711] [10.1016/j.aca.2020.11.016] |
25. Xingchu Gong, Jingyuan Shao, Shangxin Guo, Jingjing Pan, Xiaohui Fan. (2021) Determination of inhibitory activity of Salvia miltiorrhiza extracts on xanthine oxidase with a paper-based analytical device. Journal of Pharmaceutical Analysis, 11 (603). [PMID:34765273] [10.1016/j.jpha.2020.09.004] |
26. Xiao-Wei Zhang, Mei Zhou, Lin An, Ping Zhang, Ping Li, Jun Chen. (2020) Lipophilic Extract and Tanshinone IIA Derived from Salvia miltiorrhiza Attenuate Uric Acid Nephropathy through Suppressing Oxidative Stress-Activated MAPK Pathways. AMERICAN JOURNAL OF CHINESE MEDICINE, 48 (6): (1455-1473). [PMID:32933312] [10.1142/S0192415X20500718] |
27. Wen Weng, Qilong Wang, Chunmei Wei, Na Man, Kangyi Zhang, Qiuyu Wei, Michael Adu-Frimpong, Elmurat Toreniyazov, Hao Ji, Jiangnan Yu, Ximing Xu. (2019) Preparation, characterization, pharmacokinetics and anti-hyperuricemia activity studies of myricitrin-loaded proliposomes. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 572 (118735). [PMID:31705971] [10.1016/j.ijpharm.2019.118735] |
28. Zhang Kangyi, Wang Qilong, Yang Qiuxuan, Wei Qiuyu, Man Na, Adu-Frimpong Michael, Toreniyazov Elmurat, Ji Hao, Yu Jiangnan, Xu Ximing. (2019) Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System. AAPS PHARMSCITECH, 20 (5): (1-11). [PMID:31187334] [10.1208/s12249-019-1421-0] |
29. Yin Wan, Fen Wang, Bin Zou, Yuefeng Shen, Yizhen Li, Axi Zhang, Guiming Fu. (2019) Molecular mechanism underlying the ability of caffeic acid to decrease uric acid levels in hyperuricemia rats. Journal of Functional Foods, 57 (150). [10.1016/j.jff.2019.03.038] |
30. Tianqiao Yong, Shaodan Chen, Yizhen Xie, Diling Chen, Jiyan Su, Ou Shuai, Huiping Hu, Dan Zuo, Danling Liang. (2018) Hypouricemic Effects of Armillaria mellea on Hyperuricemic Mice Regulated through OAT1 and CNT2. AMERICAN JOURNAL OF CHINESE MEDICINE, 46 (3): (585-599). [PMID:29595077] [10.1142/S0192415X18500301] |
31. Yin Wan, Yu-Xi Liang, Bin Zou, Gui-Ming Fu, Ming-Yong Xie. (2018) The possible mechanism of hydroxytyrosol on reducing uric acid levels. Journal of Functional Foods, 42 (319). [10.1016/j.jff.2018.01.009] |
32. Jing Wang, Dongfang Shi, Meizhu Zheng, Bing Ma, Jing Cui, Chunming Liu, Chengyu Liu. (2017) Screening, separation, and evaluation of xanthine oxidase inhibitors from Paeonia lactiflora using chromatography combined with a multi-mode microplate reader. JOURNAL OF SEPARATION SCIENCE, 40 (21): (4160-4167). [PMID:28857450] [10.1002/jssc.201700690] |
33. Zeynep Tohtahon, Lu Zhang, Jianxin Han, Xing Xie, Zongcai Tu, Tao Yuan. (2017) Extraction optimization, structural characterization and bioactivity evaluation of triterpenoids from hawthorn (Crataegus cuneata) fruits. JOURNAL OF FOOD BIOCHEMISTRY, 41 (4): (e12377). [10.1111/jfbc.12377] |
34. Hongjin Tang, Lin Yang, Wei Li, Jiahuang Li, Jun Chen. (2016) Exploring the interaction between Salvia miltiorrhiza and xanthine oxidase: insights from computational analysis and experimental studies combined with enzyme channel blocking. RSC Advances, 6 (114): (113527-113537). [10.1039/C6RA24396G] |
35. Yin Wan, Bin Zou, Hailong Zeng, Lunning Zhang, Ming Chen, Guiming Fu. (2016) Inhibitory effect of verbascoside on xanthine oxidase activity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 93 (609). [PMID:27616694] [10.1016/j.ijbiomac.2016.09.022] |
36. Fu Yu, Mo Hua-Yan, Gao Wen, Hong Jia-Ying, Lu Jun, Li Ping, Chen Jun. (2014) Affinity selection-based two-dimensional chromatography coupled with high-performance liquid chromatography-mass spectrometry for discovering xanthine oxidase inhibitors from Radix Salviae Miltiorrhizae. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 406 (20): (4987-4995). [PMID:24866714] [10.1007/s00216-014-7902-9] |